The Sydney Myopia Study: Prevalence And Risk Factors For Myopia And Other Eye Conditions In School-age Children.
Funder
National Health and Medical Research Council
Funding Amount
$596,375.00
Summary
This study aims to establish the exact extent of increasing levels of myopia in young Australians and the frequency of other treatable eye conditions such as reduced vision in one eye (amblyopia) and squint. We also aim to exam in detail, risk factors associated with myopia, such as parental myopia, living conditions and educational pressures, particularly those associated with reading and other forms of near-work. Increased understanding of factors leading to increasing myopia prevalence may en ....This study aims to establish the exact extent of increasing levels of myopia in young Australians and the frequency of other treatable eye conditions such as reduced vision in one eye (amblyopia) and squint. We also aim to exam in detail, risk factors associated with myopia, such as parental myopia, living conditions and educational pressures, particularly those associated with reading and other forms of near-work. Increased understanding of factors leading to increasing myopia prevalence may enable design of preventive strategies that could limit future increases in the ocurrence of myopia in Australia. The prevalence of myopia is increasing world-wide. In many Asian countries, it has reached epidemic proportions (80-90%) in young, educated people. In many other countries close to half the younger population is now short-sighted. Data from the Blue Mountains Eye Study and Melbourne Visual Impairment Project in older persons have suggested that the prevalence of myopia is increasing in Australia. Comparison with our recent pilot study on school children indicates that myopia prevalence has increased 2 to 3-fold in recent decades. Myopia or short-sightedness is now one of the five major causes of blindness. In countries where the prevalence of myopia is high, it is one of the top three. Myopia requires expensive optical and-or surgical correction of the refractive error for visual functioning. Unfortunately correction does not prevent the development of visual impairment and blindness from complications of myopia. Late in life, even low myopia is associated with an increased risk of both glaucoma and cataract. Myopia therefore imposes additional major health costs because of the burden of eye disease and the support costs for people affected by myopia-associated low vision or blindness. With increasing prevalence, the health care costs of myopia are likely to continue to rise in Australia.Read moreRead less
Adverse Outcomes Following Cataract Surgery In Western Australia: A Population Study Using Record Linkage
Funder
National Health and Medical Research Council
Funding Amount
$359,150.00
Summary
Cataract is a major cause of correctable visual loss with surgery the only treatment available. Cataract surgery is now one of the most commonly performed operations. With the ageing population, the number of operations is set to double within the next 12 years in Western Australia, from 10,000 procedures a year currently. Although surgery is successful in most cases, complications do occur. Endophthalmitis (infection of internal structures of the eye), incomplete cataract removal, detachment of ....Cataract is a major cause of correctable visual loss with surgery the only treatment available. Cataract surgery is now one of the most commonly performed operations. With the ageing population, the number of operations is set to double within the next 12 years in Western Australia, from 10,000 procedures a year currently. Although surgery is successful in most cases, complications do occur. Endophthalmitis (infection of internal structures of the eye), incomplete cataract removal, detachment of the retina and corneal decompensation (opacity of the clear front of the eye) are four major complications of cataract surgery. These complications may cause blindness and are expensive to treat. We propose to investigate these serious, potentially blinding, complications of cataract surgery by measuring how often these complications occur and to examine if changes in surgical technique over the past 20 years have resulted in better outcomes. We will also evaluate risk factors for endophthalmitis; and determine the quality of life and economic costs of endophthalmitis after cataract surgery. Our study findings will enable us to better inform eye surgeons, the general community, health policy makers and the scientific community about the cost versus safety of different forms of cataract surgery. Unless effective strategies can be found to reduce the rate of complications, the personal and community burden of these devastating complications will only increase as the number of operations continues to increase.Read moreRead less
ENDOPHTHALMITIS IN WESTERN AUSTRALIA (1980-2002): INCIDENCE, MANAGEMENT AND EFFECTIVENESS OF CHEMOPROPHYLAXIS
Funder
National Health and Medical Research Council
Funding Amount
$348,942.00
Summary
Endophthalmitis is a serious sight threatening infection of the internal cavities of the eye. Although endophthalmitis is not a common post-operative complication of eye surgery, 200 cases of this serious sight threatening infection occur each year in Australia following cataract surgery. Not only is this condition extremely distressing to the patients and surgeons alike, around A$4 million per year is spent each year treating the infection. Also, there is significant expenditure on methods to p ....Endophthalmitis is a serious sight threatening infection of the internal cavities of the eye. Although endophthalmitis is not a common post-operative complication of eye surgery, 200 cases of this serious sight threatening infection occur each year in Australia following cataract surgery. Not only is this condition extremely distressing to the patients and surgeons alike, around A$4 million per year is spent each year treating the infection. Also, there is significant expenditure on methods to prevent the infection that have not, as yet, been demonstrated beneficial. Our study will use a multidisciplinary team consisting of consultant ophthalmologists, public health researchers, a biostatistician and health economist to assess the impact of endophthalmitis in WA from 1980-2002 (around 480 cases). The population-based WA Linked Database provides a unique opportunity to produce what will be the largest population study of endophthalmitis. Data from the study will provide important information to develop best-practice treatment guidelines to prevent endophthalmitis following cataract surgery. The significance of this study will be that accurate information on the clinical epidemiology and true cost of endophthalmitis will be obtained for WA. By studying the records of patients with endophthalmitis and comparing them with matched patients, who did not have post-operative endophthalmitis following cataract surgery, we will characterise the risks for this severe complication by identifying the underlying factors that are responsible for the infection. We will also better understand the effect of methods used to prevent the infection. The use of a whole population-based study to assess methods of endophthalmitis prevention has not been done before and will have a significant beneficial impact on health policy and best-practice, not only in Australia, but also internationally.Read moreRead less
Evaluation And Planning Of Coronary Revascularization Services.
Funder
National Health and Medical Research Council
Funding Amount
$591,527.00
Summary
This project concerns operations to unblock or bypass the coronary arteries that supply the muscle of the heart. The project has two parts. One is concerned with checking that changes in medical and surgical treatment of coronary artery disease have been followed by improvements in survival of affected patients. The second will use data on changes in the Australian population, changes in the frequency of heart disease and changes in treatments for heart disease to predict how many coronary opera ....This project concerns operations to unblock or bypass the coronary arteries that supply the muscle of the heart. The project has two parts. One is concerned with checking that changes in medical and surgical treatment of coronary artery disease have been followed by improvements in survival of affected patients. The second will use data on changes in the Australian population, changes in the frequency of heart disease and changes in treatments for heart disease to predict how many coronary operations will be needed in Australia over the next decade. This is a vital step in planning hospital services for patients with coronary disease.Read moreRead less