Molecular Pharmacology Of Chemokine Receptor Signalling In Cancer
Funder
National Health and Medical Research Council
Funding Amount
$371,770.00
Summary
Molecular pharmacology is the study of how hormones, neurotransmitters and pharmaceuticals interact with our cells through receptors, which transfer a signal across the cell membrane to change the function of that cell. Chemokine receptors are recognised to play a role in the development of many cancers. Understanding how these receptors work has enormous implications for improving our ability to develop better anti-cancer treatments with fewer side effects.
Information Systems Enabled Corporate Transformation: Evaluation of Electronic Customer Relationship Management in the Service Sector. Customer relationship management (CRM) is a business and marketing strategy that integrates technology, process and business activities around the customer. Only 30% of electronic CRM efforts have been successfully implemented because stakeholder expectations are typically neglected. This issue underlines the importance of the ?soft? organisational issues involve ....Information Systems Enabled Corporate Transformation: Evaluation of Electronic Customer Relationship Management in the Service Sector. Customer relationship management (CRM) is a business and marketing strategy that integrates technology, process and business activities around the customer. Only 30% of electronic CRM efforts have been successfully implemented because stakeholder expectations are typically neglected. This issue underlines the importance of the ?soft? organisational issues involved with the evaluation of information systems. By evaluating the change management process and modelling the impact of e-CRM enabled change, management strategies will be developed to enable its successful implementation. The research will provide a greater understanding for evaluating the performance of e-CRM solutions, as well as uncover opportunities for organisational related change.Read moreRead less
Developing New Therapeutic Strategies For Brain Cancer
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
Each year, over 1,500 Australians will develop brain cancer. Unlike many cancers, it cannot be prevented by lifestyle changes. Adults with brain cancer usually die within 2 years. The overall aims of this funding are to extend patients' lives and build brain cancer research in Australia so that we have the best chance of curing this disease. The expected outcome is clinical trial of drug candidates for the most common and most deadly brain cancer, high-grade glioma.
Strategic evaluation model for business-to-business electronic marketplace participation. Striving to become a knowledge-based nation is dependent upon the effective adoption, diffusion and implementation of ICT throughout the business community. The developing world markets, brought about by e-commerce and the increased ability to trade globally facilitated by e-markets, have created significant opportunities for Australian organisations. This research will produce a dynamic model that can be ....Strategic evaluation model for business-to-business electronic marketplace participation. Striving to become a knowledge-based nation is dependent upon the effective adoption, diffusion and implementation of ICT throughout the business community. The developing world markets, brought about by e-commerce and the increased ability to trade globally facilitated by e-markets, have created significant opportunities for Australian organisations. This research will produce a dynamic model that can be used to not only evaluate e-marketplace participation but a wide range of Internet applications. The research will provide Australian managers with the foundation of knowledge needed to guide and support their decision-making when implementing new technology.Read moreRead less
Dynamic Life Cycle Evaluation of Customer Relationship Management Systems. Striving to become a knowledge based nation is dependent upon effective adoption, diffusion and implementation of information and communication technology thoughout the business community. This research will produce a dynamic model that can be used to evaluate enterprise wide applications such as electronic Customer Relationship Management (CRM) so that managers can examine the impact of new tehnology on business processe ....Dynamic Life Cycle Evaluation of Customer Relationship Management Systems. Striving to become a knowledge based nation is dependent upon effective adoption, diffusion and implementation of information and communication technology thoughout the business community. This research will produce a dynamic model that can be used to evaluate enterprise wide applications such as electronic Customer Relationship Management (CRM) so that managers can examine the impact of new tehnology on business processes. In addition, the research will provide managers wit the foundation of knowledge needed to guide and support their decision-making when implementing new technology. Read moreRead less
Classifying the indirect costs of information systems and information technology in business. Many businesses are increasing their expenditure on IS/IT to obtain a strategic competitive advantage. Traditional approaches to IS/IT appraisal are unable to accommodate the costs associated with deploying 'organisational-wide' IS/IT solutions because of their qualitative characteristics. The inability of managers to determine the 'true' costs of IS/IT are attributable to a lack of knowledge and unders ....Classifying the indirect costs of information systems and information technology in business. Many businesses are increasing their expenditure on IS/IT to obtain a strategic competitive advantage. Traditional approaches to IS/IT appraisal are unable to accommodate the costs associated with deploying 'organisational-wide' IS/IT solutions because of their qualitative characteristics. The inability of managers to determine the 'true' costs of IS/IT are attributable to a lack of knowledge and understanding of IS/IT related costs. This research will extend the myopia of traditional 'direct' financial cost analysis by identifying 'indirect' cost factors. A model that integrates cost taxonomies and performance measures/metrics of IS/IT will be developed as a frame of reference for IS/IT decision-makers.Read moreRead less
Designing an Intelligent Process Operation Management System. The complexity and sophistication of current generation of industrial processes, and the growing need for autonomous agents that control physical systems, motivate the need for the development of an intelligent process operation management system. In this project, the innovative integration of theories from different scientific fields (computer systems, process engineering, systems and control engineering) provides an excellent platfo ....Designing an Intelligent Process Operation Management System. The complexity and sophistication of current generation of industrial processes, and the growing need for autonomous agents that control physical systems, motivate the need for the development of an intelligent process operation management system. In this project, the innovative integration of theories from different scientific fields (computer systems, process engineering, systems and control engineering) provides an excellent platform for development of a smart data management tool, to oversee the major operational tasks within the plant and help the operators and engineers to make more informed decisions. Direct application of the techniques developed in this study to a pilot case study, could be used as a benchmark to show the potential benefits that can be gained through smart information use and data management.Read moreRead less
A Structural Investigation Into The T-cell Response To Epstein Barr Virus Infection
Funder
National Health and Medical Research Council
Funding Amount
$549,000.00
Summary
X-ray crystallography is an essential tool for solving the three-dimensional structure of proteins. Proteins control the biological processes within the cell and it is the precise shape of proteins that determines how they function. Depending on the particular sequence of the amino acids, the so-called building unit of the proteins, the protein molecule bends and forms a distinct, complex shape. This specific three-dimensional shape allows the protein to undertake its specific function, such as ....X-ray crystallography is an essential tool for solving the three-dimensional structure of proteins. Proteins control the biological processes within the cell and it is the precise shape of proteins that determines how they function. Depending on the particular sequence of the amino acids, the so-called building unit of the proteins, the protein molecule bends and forms a distinct, complex shape. This specific three-dimensional shape allows the protein to undertake its specific function, such as binding to other proteins, acting as an enzyme or interacting with nucleic acids. To determine how a protein acts, it is vital to know the precise three-dimensional shape at the atomic level. This proposal is concerned with understanding the precise shape of proteins that control the immune response to Epstein Barr Virus. Epstein Barr Virus is an ubiquitous human pathogen that has being linked to a number of cancers. This work will further our understanding of the immune response to Epstein Barr Virus.Read moreRead less
Special Research Initiatives - Grant ID: SR0354729
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Smart Use of Information Technologies (SUITs). The SUITs network will develop critical mass in world-class, leading-edge research into the smart use of information and communication technology (ICT) through integration of research within the dispersed Australian ICT research community and through facilitating international linkages. The network will undertake research applicable in key sectors including the health, education, service, knowledge and media industries. The aim is to establish a h ....Smart Use of Information Technologies (SUITs). The SUITs network will develop critical mass in world-class, leading-edge research into the smart use of information and communication technology (ICT) through integration of research within the dispersed Australian ICT research community and through facilitating international linkages. The network will undertake research applicable in key sectors including the health, education, service, knowledge and media industries. The aim is to establish a higher order of coordination and collaboration in research into ICT applications.
The feasibility study proposed will engage key stakeholders, refine research goals and investigate linkage mechanisms to improve Australia's ICT research and its contribution to economic and social well-being.
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Improving organisational innovation using social media. This project will examine how social media can be effectively used in organisations to improve levels of innovation. The outcomes of the research will put Australia at the forefront of research in the area and have a significant impact on innovation in Australian organisations.