How Does NF-kB2 Regulate Thymic Selection To Prevent Organ-specific Autoimmune Disease?
Funder
National Health and Medical Research Council
Funding Amount
$787,600.00
Summary
Autoimmune diseases like type 1 diabetes and thyroiditis arise from defects that cause the immune system to confuse self and non-self. Normally, this distinction is programmed in the thymus. We recently identified the gene that causes a form of autoimmune disease. We also made an important discovery about how the thymus gland regulates self-non-self discrimination. We will build on these two discoveries to gain a precise understanding of how the immune system normally avoids autoimmune disease.
Developing Reliable Bio-Crypto Features for Mobile Template Protection. Cost of identity theft crimes were at multi-million dollars in Australia in 2007. Technically this is due to the fact that conventional personal identification number and token based security mechanisms cannot identify genuine users. Biometric fingerprint security systems emerge as a promising solution. However protection of the mobile embedded fingerprint template itself is an unresolved problem. The project aims to devel ....Developing Reliable Bio-Crypto Features for Mobile Template Protection. Cost of identity theft crimes were at multi-million dollars in Australia in 2007. Technically this is due to the fact that conventional personal identification number and token based security mechanisms cannot identify genuine users. Biometric fingerprint security systems emerge as a promising solution. However protection of the mobile embedded fingerprint template itself is an unresolved problem. The project aims to develop new ways designing bio-cryptosystems that provide strong security strength. The project will bring new body of knowledge into this field and place Australia in the forefront of this research, and also result in strengthened security of IT infrastructure and systems for industries.Read moreRead less
ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this te ....ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this team with the foremost international authorities and leading industry players in the area of sensor networks. This research network will guide collaborative research that will ensure Australia to play a world leading role in sensor network development and implementation.
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Using data mining methods to remove uncertainties in sensor data streams. This project will develop key techniques for removing uncertainties in sensor data streams and thus improve the monitoring quality of sensor networks. The expected outcomes will benefit Australia by enabling improved, lower-cost monitoring of natural resources and management of stock raising.
Special Research Initiatives - Grant ID: SR0354604
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Network in Imaging Science and Technology. The ARC Network in Imaging Science and Technology is a field of research network covering the fundamental science and technological development of applied imaging systems. The network will encompass all aspects of the imaging sciences from image formation, through image processing and analysis, and on to image visualisation. In particular, the network will focus on a number of application areas that utilise these core technologies: medical imaging; ....ARC Network in Imaging Science and Technology. The ARC Network in Imaging Science and Technology is a field of research network covering the fundamental science and technological development of applied imaging systems. The network will encompass all aspects of the imaging sciences from image formation, through image processing and analysis, and on to image visualisation. In particular, the network will focus on a number of application areas that utilise these core technologies: medical imaging; surveillance and security; materials science and metallurgy; environmental monitoring; and consumer imaging. In this way, the network will provide an environment for creative inter-disciplinary research to the socio-economic benefit of Australia.Read moreRead less
Special Research Initiatives - Grant ID: SR0566892
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
The EarthByte software and database system. Earth processes over geological timescales cannot be understood outside of a plate tectonic context. However, no standard tool exists to explore the causes and effects of lithosphere-mantle interaction in accordance with past plate configurations. Our aim is to develop a Palaeo-Geographic Information System called EarthByte that will connect the open source and architecture-independent GPlates and GMT software, and implement XML-based service interfac ....The EarthByte software and database system. Earth processes over geological timescales cannot be understood outside of a plate tectonic context. However, no standard tool exists to explore the causes and effects of lithosphere-mantle interaction in accordance with past plate configurations. Our aim is to develop a Palaeo-Geographic Information System called EarthByte that will connect the open source and architecture-independent GPlates and GMT software, and implement XML-based service interfaces and databases. EarthByte will create the foundation for an e-geoscience framework for grid-based data access and Earth process modelling by linking geological and geophysical observations to palaeogeographic models for constraining mantle convection and lithospheric deformation.Read moreRead less
Biofocussed Prostate Cancer RadioTherapy (BiRT): A Personalised Approach To Delivering The Right Dose To The Right Place
Funder
National Health and Medical Research Council
Funding Amount
$753,565.00
Summary
We propose a new approach to treating prostate cancer with radiotherapy to move from the standard whole prostate treatment to a personalised treatment that varies radiation intensity throughout the prostate. We will mathematically combine features that influence radiotherapy effect from advanced imaging, clinical and biopsy information. This model will map out the radiotherapy dose required at each part of the prostate, to maximise killing of the cancer whilst minimising harm to normal tissue
Integrated Intelligent Decision Support for Field Design and Management of Census Operations in Australia. This project contributes to a more reliable and accurate measurement of the number and key characteristics of Australian people by supporting a more efficient and effective field design and management of the Census operations. As the Census provides a snapshot of Australia and is crucial to communities, private institutions and all levels of government in the planning of services and facili ....Integrated Intelligent Decision Support for Field Design and Management of Census Operations in Australia. This project contributes to a more reliable and accurate measurement of the number and key characteristics of Australian people by supporting a more efficient and effective field design and management of the Census operations. As the Census provides a snapshot of Australia and is crucial to communities, private institutions and all levels of government in the planning of services and facilities, this project not only addresses the research priority of smart information use, but also contributes to strengthening Australia's social and economic fabric. This project will also train highly qualified IT specialists critical to Australia's scientific and industrial development, thus increasing our competitiveness in information technology R&D.Read moreRead less