Understanding Gene-environment Interactions In Relation To Risk Of Age-related Cataract
Funder
National Health and Medical Research Council
Funding Amount
$86,514.00
Summary
Age-related cataract is the clouding of the lens, a leading cause of visual impairment among older persons. The burden of this common eye disease will only increase as the population ages. Besides age, other environmental and genetic risk factors that increase the risk of cataract have been identified. The aim of this research is to examine how the interplay of genes and environment contributes to age-related cataract formation, using population-based data of established studies.
Genetic And Environmental Risk Factors On Lifetime Risk Of Obstructive Lung Disease
Funder
National Health and Medical Research Council
Funding Amount
$351,414.00
Summary
Classification of lifetime phenotypes of obstructive lung disease allows investigation of the effect of environmental and genetic influences on specific phenotypes along with the interactions between them. Through improved phenotyping ,the currently inconsistent relationships between asthma and COPD and their associations with genetic and environmental factors may become clearer.
Do Breast Cancer Risk Factors Differ According To Underlying Genetic Susceptibility? A Pooled Analysis Of Prospective Studies From The NCI Cancer Cohort Consortium
Funder
National Health and Medical Research Council
Funding Amount
$418,581.00
Summary
We propose to use data from 23 international prospective cohort studies in the Cancer Cohort Consortium organised by the US National Cancer Institute to evaluate gene environment interactions for women who are at increased genetic risk of breast cancer. Our ultimate goal is to enhance the performance of clinical prediction tools and to develop targeted evidence-based strategies to mitigate the high absolute risk of breast cancer for women at increased genetic risk of the disease.
Determining The Role Of Vitamin D In The Development Of Asthma And Allergic Diseases In High Risk Families
Funder
National Health and Medical Research Council
Funding Amount
$351,127.00
Summary
Allergic diseases like asthma, eczema and hay-fever, prevent our children from getting a healthy start to life, and we don’t know how to prevent these conditions. Vitamin D levels may be critical in the development of childhood asthma and allergies, and they can be easily modified! Using a group of 620 children who we have followed for 20 years, we will identify the role of vitamin D levels in the development of allergic conditions, and factors that modify these relationships.
An Investigation Of The Role Of Gene-environment Interactions And Epigenetics In Depression: Nature Combined With Nurture.
Funder
National Health and Medical Research Council
Funding Amount
$337,602.00
Summary
Depression is one of the biggest public health problems, yet the causes remain largely unknown. This study aims to determine how environmental factors can combine with particular genes to increases an individual’s risk of depression. Environmental factors can also cause modifications to genes which can affect an individual’s health. This study will thus also examine whether women with post-natal depression and their children have different gene modifications than those without depression.
The aim of my research is to investigate the role that physical activity and sedentary behaviour (too much sitting) play in the development of cancer. My research will increase our understanding of how physical activity and sedentary behaviour influence cancer, and may lead to new strategies for cancer prevention.
Discovery Early Career Researcher Award - Grant ID: DE220100847
Funder
Australian Research Council
Funding Amount
$394,868.00
Summary
RECONNECT ME: REgaining CONtrol of childreN’s EleCTronic MEdia . This project aims to understand the impact that screen behaviours have on children’s quality of life, social skills and family functioning, and co-design feasible, acceptable and effective behavioural and digital strategies to mitigate this impact. Parents are concerned and are seeking urgent help in the persistent and evolving technology climate, where previous strategies are no longer relevant. Expected outcomes include new knowl ....RECONNECT ME: REgaining CONtrol of childreN’s EleCTronic MEdia . This project aims to understand the impact that screen behaviours have on children’s quality of life, social skills and family functioning, and co-design feasible, acceptable and effective behavioural and digital strategies to mitigate this impact. Parents are concerned and are seeking urgent help in the persistent and evolving technology climate, where previous strategies are no longer relevant. Expected outcomes include new knowledge of the impact of screen time, and the co-design of innovative and user-friendly strategies developed with families, for families, to manage this. The benefits will include informing future effective and scalable screen time strategies for improved quality of life, social skills, family functioning outcomes.Read moreRead less