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Insect host/vector genetic responses to rhabdovirus infection. Rhabdoviruses cause important diseases in humans, animals and plants. These viruses are transmitted by insect vectors in which they persist and propagate, an intimate and specific association. Insect-rhabdovirus interactions will be studied at the molecular level using a planthopper-maize rhabdovirus model. Insect genes specifically induced by rhabdovirus infection as well as the viral genes themselves will be identified and characte ....Insect host/vector genetic responses to rhabdovirus infection. Rhabdoviruses cause important diseases in humans, animals and plants. These viruses are transmitted by insect vectors in which they persist and propagate, an intimate and specific association. Insect-rhabdovirus interactions will be studied at the molecular level using a planthopper-maize rhabdovirus model. Insect genes specifically induced by rhabdovirus infection as well as the viral genes themselves will be identified and characterized using genomics and bioinformatics tools. We will extend the same approaches to a comparative analysis of these planthopper genes with other insect-rhabdovirus systems under investigation in our institutes. Identification of viral genes expressed in insects, the insect genes that respond to virus infection, and interpretation of the roles of these genes in insects, may indicate new opportunities to control serious plant and animal diseases through control of virus transmission.Read moreRead less
Comparative studies of invasive plants: a leaf carbon strategy approach. Invasion of communities by exotic plants is a significant threat to biodiversity globally. This proposal is to strengthen collaborative links between the Plant Invasion Research Laboratories of Leishman in Australia and Richardson in South Africa. Their current research seeks to understand strategies of invasive plants in novel environments using the framework of leaf carbon strategies. Australian plants invasive in South A ....Comparative studies of invasive plants: a leaf carbon strategy approach. Invasion of communities by exotic plants is a significant threat to biodiversity globally. This proposal is to strengthen collaborative links between the Plant Invasion Research Laboratories of Leishman in Australia and Richardson in South Africa. Their current research seeks to understand strategies of invasive plants in novel environments using the framework of leaf carbon strategies. Australian plants invasive in South Africa and South African plants invasive in Australia provide an ideal model system. This collaborative research will enable better prediction of potential invaders, as well as providing important input for models of plant, ecosystem and biosphere responses to global change incorporating invasion dynamics.Read moreRead less
Post-invasion trait-mediated indirect interactions: ecological and evolutionary impacts of the invasive European green crab. A multitude of ecological interactions determine the success and impacts of invasive species. We will advance current knowledge of the impacts of invasive European green crabs in Australia by detailing ecological and evolutionary interactions with native molluscs. This information will be useful in understanding the crab's invasion success and impacts on native communiti ....Post-invasion trait-mediated indirect interactions: ecological and evolutionary impacts of the invasive European green crab. A multitude of ecological interactions determine the success and impacts of invasive species. We will advance current knowledge of the impacts of invasive European green crabs in Australia by detailing ecological and evolutionary interactions with native molluscs. This information will be useful in understanding the crab's invasion success and impacts on native communities in Australia and other regions invaded by the crab worldwide. More broadly, this work will provide an evolutionary perspective of post-invasion processes that has been substantiated in terrestrial systems but is often lacking in marine systems. Read moreRead less
MitoGenomics of Key Pathogens - An International Research Co-operative. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by pr ....MitoGenomics of Key Pathogens - An International Research Co-operative. The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national objectives, including the maintenance of a strong capability in basic research, the development of new scientific concepts and the enhancement of international collaborative links; (2) to strengthen the links between basic and applied research; (3) to develop excellence in research by promoting collaborative research, resulting in a more efficient use of resources in a national and international context; (4) to enhance the skills-base in biology and biotechnology; (5) to substantially increase global visibility through quality research, leading to an increased investment in Australian science.Read moreRead less
Long-term natural ecological consequences of disturbance on coral reefs: the benthic foraminifera perspective. The tropical coastline of Australia encompasses world-renowned coral reefs (Great Barrier Reef and Ningaloo Marine Park). Even these reefs are not pristine and are increasingly susceptible to disturbance from human impact. The long-term ecological effects of disturbance on reef communities cannot be experimentally determined; but natural experiments from the fossil record provide mech ....Long-term natural ecological consequences of disturbance on coral reefs: the benthic foraminifera perspective. The tropical coastline of Australia encompasses world-renowned coral reefs (Great Barrier Reef and Ningaloo Marine Park). Even these reefs are not pristine and are increasingly susceptible to disturbance from human impact. The long-term ecological effects of disturbance on reef communities cannot be experimentally determined; but natural experiments from the fossil record provide mechanisms to ensure that managers of Australia's reefs have critical information on how past disturbance frequency and intensity has affected coral reef communities. This information will help ensure the continuation of ecosystem goods and services from Australia's high diversity coral reefs.Read moreRead less
Evolution of host relationships among the parasitic wasps inferred from morphology, DNA sequences and mitochondrial genome organisation. The parasitic Hymenoptera (wasps) are extensively used as biological control agents of agricultural and horticultural pests worldwide, but detailed information on their evolutionary relationships, how they have coevolved with major host groups, and the patterns of host relationships across various wasp families are lacking. This project will employ DNA sequence ....Evolution of host relationships among the parasitic wasps inferred from morphology, DNA sequences and mitochondrial genome organisation. The parasitic Hymenoptera (wasps) are extensively used as biological control agents of agricultural and horticultural pests worldwide, but detailed information on their evolutionary relationships, how they have coevolved with major host groups, and the patterns of host relationships across various wasp families are lacking. This project will employ DNA sequence data from 'new' genes, information on mitochondrial genome organisation, as well as morphology, to generate robust phylogenies for braconid and scelionid wasps that can be used to determine patterns of host utilisation and predict hosts for wasp groups where this information is currently unknown.Read moreRead less
Pharmacological and biochemical characterisation of Australian mygalomorph spider venoms. This project will increase our limited knowledge of Australian mygalomorph venoms by isolation, identification and characterisation of novel toxins in theraphosid and Northern mouse-spider venoms. Thereby, the scientific basis for the treatment of mygalomorph spider bites might be improved. Secondly, new insights into pharmacology and the potential development of novel therapeutics and molecular probes of t ....Pharmacological and biochemical characterisation of Australian mygalomorph spider venoms. This project will increase our limited knowledge of Australian mygalomorph venoms by isolation, identification and characterisation of novel toxins in theraphosid and Northern mouse-spider venoms. Thereby, the scientific basis for the treatment of mygalomorph spider bites might be improved. Secondly, new insights into pharmacology and the potential development of novel therapeutics and molecular probes of target molecules might be expected.Read moreRead less
Pesticide effects on native Australia vetebrates: A collaboration between the University of Wollongong and Texas Tech University. Aerially applied insecticides are used worldwide to control periodic locust infestations. Assessment of their effects on vertebrates is based on limited information concerning a few North American or European species. We will compare the sublethal effects of 3 compounds currently used or under consideration by the Australian Plague Locust Commission (APLC) on repre ....Pesticide effects on native Australia vetebrates: A collaboration between the University of Wollongong and Texas Tech University. Aerially applied insecticides are used worldwide to control periodic locust infestations. Assessment of their effects on vertebrates is based on limited information concerning a few North American or European species. We will compare the sublethal effects of 3 compounds currently used or under consideration by the Australian Plague Locust Commission (APLC) on representative Australian vertebrates. Assessments include cholinesterase inhibition, peak aerobic performance , thermoregulatory ability, stress responses, immune function and feeding behaviour. Our collaboration includes expertise in comparative physiology, endocrinology and wildlife toxicology.Read moreRead less