Treatment Of Invasively Ventilated Adults With Early Activity And Mobilisation
Funder
National Health and Medical Research Council
Funding Amount
$1,467,137.00
Summary
The sickest patients in intensive care units (ICUs) receive prolonged, invasive support for their breathing. This is currently managed with complete bed rest, and results in severe muscle weakness, increased duration of hospital stay and poor recovery. We have found that early activity and mobilisation during invasive breathing support is safe and may improve survival and recovery. We will test early activity and mobilisation in a large randomised controlled trial of 750 ICU patients.
Improving Access To Psychological Services For People With Cancer: A Randomised Control Trial Of An Interactive Web-Based Intervention
Funder
National Health and Medical Research Council
Funding Amount
$612,715.00
Summary
Approximately 35% of people diagnosed with cancer will experience persistent significant distress, and unmet psychological supportive care needs in Australian cancer patients are highly prevalent. The web presents a unique method of delivery of supportive care. However, to our knowledge this type of intervention has not been examined. This two-phased study will develop and test a novel web-based intervention to improve psychological outcomes in cancer patients experiencing distress.
Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.
Improving School Transition By Improving Child Sleep: A Translational Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$745,827.00
Summary
A successful transition to school sets a child on a path for life. A poor transition can lead to early drop out, poor peer relationships and poor emotional skills. In 2008/09, we found that a brief sleep intervention for children improved key determinants of a successful transition including social-emotional functioning and parent mental health. We now plan to see if the same intervention, delivered by school nurses, can have a similar effect.
The Central Australian Heart Protection Study: A Randomised Trial Of Nurse-Led, Family Based Secondary Prevention Of Acute Coronary Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$1,923,630.00
Summary
Despite the high burden of cardiovascular diseases among Indigenous Australians, few intervention trials have sought to evaluate novel approaches to reducing differential outcomes in this vulnerable group. The Central Australian Heart Protection Study seeks to test the effectiveness of a nurse-led, family based education and assessment program in reducing the incidence of poor outcomes in indigenous and non-indigenous patient’s following an Acute Coronary Syndrome (ACS).
Preventing Early Academic Problems By Improving Working Memory: Translational Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$831,085.00
Summary
Learning difficulties are common and can cause school failure and poor self-esteem. They are associated with specific problems with temporarily remembering and using information (‘working memory’). Research suggests that improving working memory might improve academic achievement. We will study this intervention in a large group of primary school children who have poor working memory. If successful, the intervention will provide a way to improve the learning skills of these high-risk children.