SUcceSS: SUrgery For Spinal Stenosis - A Randomised Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,303,245.00
Summary
This will be the first placebo-controlled randomised trial of surgery for lumbar spinal stenosis and aims to determine the efficacy and safety of this intervention in decreasing pain and improving disability in this population. The cost-effectiveness of surgery for lumbar spinal stenosis will also be determined.
A Randomised Controlled Trial Of Daily Antibacterial Mouthwash To Reduce Pharyngeal Gonorrhoea Among Men Who Have Sex With Men (MSM)
Funder
National Health and Medical Research Council
Funding Amount
$376,730.00
Summary
Gonorrhoea is a common sexually transmitted infection (STI) among gay men, and the throat is the commonest site of infection. There is early data to suggest Listerine mouthwash can be used to prevent gonorrhoea. Our study will examine whether men use Listerine every day will reduce the risk of gonorrhoea in the throat compared those who use another mouthwash product which does not have an effect on gonorrhoea.
Improving Skin Cancer Prevention: Motivating Preventive Behaviours Using Knowledge Of Personalised Genomic Risk Of Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$1,041,720.00
Summary
The aim of our study is to evaluate whether we can improve the Australian public’s skin cancer prevention behaviours, particularly reducing exposure to ultraviolet (UV) radiation, by giving personalised information about melanoma genetic risk. We will also explore the psycho-social, ethical, and economic implications of receiving this information. The results of our study are likely to influence the future of skin cancer prevention in Australia.
Randomised Controlled Trial Of HPV Self-sampling For Improving Participation In Cervical Screening: The IPAP Trial
Funder
National Health and Medical Research Council
Funding Amount
$534,461.00
Summary
Effectiveness of cervical cancer screening relies on maximising participation. Unlike a Pap test, an HPV test may be self-collected and this may overcome some of the barriers to Pap testing. Overseas trials have found higher uptake for HPV self-sampling (between 3-30%) compared with Pap test reminder letters. We will conduct the first randomised trial in Australia comparing home-based HPV self-sampling with a reminder letter, to evaluate whether this improves participation and followup.
M-SAKHI : Mobile Health Solutions To Help Community Providers Promote Maternal And Infant Nutrition And Health - A Community-based Cluster Randomized Controlled Trial In Rural India
Funder
National Health and Medical Research Council
Funding Amount
$2,379,427.00
Summary
The proposed research will examine the impact of the mobile phone counselling on child feeding practices, & undernutrition & cognitive development in a rural setting in India. The study aims to collect high-level evidence of whether mobile phone counselling about nutrition in pregnancy, and child feeding, directed at pregnant women and mothers in rural India will i) reduce low birthweight, ii) improve infant & child feeding, and iii) reduce child undernutrition at 24 months.
Long Term Impact Of A Community-based Cluster Randomized Controlled Trial Of Peer Counselling To Improve Infant Feeding On Growth & Cognitive Function Of Children Up To 5 Years In Urban Bangladesh
Funder
National Health and Medical Research Council
Funding Amount
$851,345.00
Summary
Bangladesh still faces high levels of inappropriate infant feeding leading to child undernutrition and delayed development. Effective programs are urgently needed to help reduce undernutrition and improve child development. This study in poor urban communities in Dhaka, Bangladesh will see if long-term counseling provided by local women to mothers about appropriate infant feeding can improve child’s nutritional status, growth and cognitive function in their children at 5 years.
A Community-based Cluster Randomized Controlled Trial In Rural Bangladesh To Evaluate The Impact Of The Use Of Iron/folic Acid Supplements Early In Pregnancy On The Risk Of Neonatal MortalityBACKGROUND An Effective Program Of Antenatal Iron/folic Ac
Funder
National Health and Medical Research Council
Funding Amount
$2,564,922.00
Summary
This community-based trial in rural Bangladesh will determine if iron/folic acid supplementation commencing in the first trimester of pregnancy significantly reduces newborn deaths, and whether this approach is cost-effective. This trial has the potential to inform international public health policy about the importance of starting antenatal iron/folic acid supplementation early to improve neonatal survival, and to help countries reach their child survival Millennium Development Goal