Advancing The Midwifery Workforce In Sydney, Australia
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
It is predicted that Australia will have a midwifery workforce crisis in the future. As such it is important to provide innovative solutions to retain midwives for the safety of women and their babies. There are few embedded strategies in place for midwives in NSW that support the wellbeing and emotionally demanding practise of midwives. This project aims to deliver empirical data that describes the impact of new structured support innovations for midwives in NSW.
Fighting Retinal Blindness: Learn From The Past, Improve The Present And Explore The Future Of Treatments For Macular Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$2,039,951.00
Summary
MG is a clinician-scientist dedicated to improving outcomes in people with macular disease. His lab research unit studies the causes and looks for new treatments for macular disease. His clinical research unit focuses on clinical trials of new treatments, both large multinational studies and other smaller studies where we test our own ideas. His observational unit analyses the outcomes of treatment in “real world” clinical practice. These 3 units will work together to fight macular blindness.
Bridging The Gap: Using Data Science To Transform Care And Health Outcomes In Kidney Transplant Recipients
Funder
National Health and Medical Research Council
Funding Amount
$1,155,135.00
Summary
Despite substantive survival and quality of life benefits compared to being on dialysis, kidney transplant recipients suffer from premature death, largely due to complications such as cancer and cardiovascular. Using big data science, we will be able to predict these complications in the context of chronic immunosuppression, find new and better ways to identify at risk individuals, to deliver effective and efficient screening and treatment strategies in this vulnerable population.
Tackling Australia’s Low Screening Participation To Prevent Bowel Cancer Deaths
Funder
National Health and Medical Research Council
Funding Amount
$2,188,416.00
Summary
Bowel cancer is Australia’s second deadliest cancer despite being largely treatable if detected early. The big problem is most people do not screen so too many cases are not detected soon enough. I will endeavour to increase screening participation by developing a range of strategies that do better at encouraging people to screen. I will then test each of them to determine which results in the highest participation within the actual National Bowel Cancer Screening Program.
Improving Influenza Vaccination Rate For The Prevention Of Cardiovascular Events
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Over the next 5 years, I will become an independent researcher and lead a program of work that improves heart care. My research will assess the association between high dose flu vaccine and the prevention of heart disease and test a general practice quality improvement program to enhance vaccination rate in Australia. This will deepen our understanding of the effect of flu vaccination and provide evidence to assist in generating guidelines/policies to help reduce heart disease among Australians.
Improving Cardiovascular Outcomes Through Better Trials
Funder
National Health and Medical Research Council
Funding Amount
$1,714,215.00
Summary
Randomised trials are the cornerstone of high quality medical practice. There is an urgent need to do more trials but there are major challenges - timely recruitment of participants, inclusion of representative patients and control of costs are issues we face every day. I will commence a series of new trials evaluating interventions for cardiovascular disease. In parallel I will develop and test innovative solutions to the practicalities of doing large-scale studies.
Pain is a prevalent condition and a major cause of disease burden. The research program will address important questions in the clinical management of pain to reduce its the enormous burden. The program will: 1) investigate whether opioid medicines and oral steroids are effective in treating acute low back pain and neck pain, and sciatica, and 2) assess and improve the appropriate use of strong pain medicines in primary care.
Motor Impairment: Physiology, Pathophysiology And Intervention
Funder
National Health and Medical Research Council
Funding Amount
$2,814,215.00
Summary
It is very common to get Motor Impairments in many diseases and disorders, such as stroke and multiple sclerosis, and even with ageing. These affect our ability to move and function properly. I will use multidisciplinary expertise in basic, applied and clinical science to answer key questions about mechanisms and management of the Motor Impairments of weakness and fatigue, impaired sensation and balance, and muscle contracture. Results will be rapidly applied in clinical populations.
Overcoming The Barriers To Treatment Of Multi-drug Resistant Gram-negative Bloodstream Infections In Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$447,603.00
Summary
There is a critical need to develop new treatments for children with antibiotic resistant infections. The most important bacteria causing resistant infections are known as Gram-negative bacteria. Doctors treating children with resistant Gram-negative infections are faced with few antibiotic options. This project will discover the most important resistant infections in Australian children, and trial a new antibiotic to help doctors to use it in the right children and at the right dose.
Healthy Diet And Weight Management In Pregnancy: Evidence To Ease A Hefty Clinical Burden.
Funder
National Health and Medical Research Council
Funding Amount
$1,705,260.00
Summary
Approximately 50% of women are overweight or obese on entering pregnancy, placing women at increased risk of well documented pregnancy complications. This proposal will: 1) Translate RCT evidence into clinical practice to provide dietary advice for pregnant women 2) Address why pregnancy interventions have not impacted weight gain despite improved maternal diet 3) Consider the key features of an intervention before conception 4) Evaluate a pilot RCT weight loss intervention