Cellular genomic approach to the pathogenesis of multiple sclerosis. This project compares the levels of gene usage in two important immune cell types between patients with multiple sclerosis and people who do not have the disease. It aims to identify the molecular basis for the disease, in order to identify new diagnostic, preventative and treatment options.
Devising ecologically sustainable restoration programs for degraded rural landscapes by integrating landscape ecology, genetics and ecophysiology. Concern about tree decline in rural landscape is widespread, and disturbingly climate change is predicted to exacerbate this problem. Past ill-considered tree plantings have proven to be economically wasteful, achieved limited ecological resilience and negligible improvement of biodiversity values. Using Tasmania as a 'model system', we will advance t ....Devising ecologically sustainable restoration programs for degraded rural landscapes by integrating landscape ecology, genetics and ecophysiology. Concern about tree decline in rural landscape is widespread, and disturbingly climate change is predicted to exacerbate this problem. Past ill-considered tree plantings have proven to be economically wasteful, achieved limited ecological resilience and negligible improvement of biodiversity values. Using Tasmania as a 'model system', we will advance this problem by undertaking research to determine how seedling establishment, tree growth, carbon storage and water use are influenced by landscape setting, management history, climate change, species type and local varieties. This research will provide a much needed evidence to devise ecologically sustainable tree-plantings in southern Australia.Read moreRead less
Biotic connectivity within the temperate Australian marine protected area network at three levels of biodiversity, communities, populations and genes. Project outcomes will improve management of coastal biodiversity through a multi-state collaboration of managers, marine ecologists, population geneticists and taxonomists. Sites most needed within marine protected area (MPA) networks for maintaining resilience of populations across seascapes will be identified, including sites with exceptional en ....Biotic connectivity within the temperate Australian marine protected area network at three levels of biodiversity, communities, populations and genes. Project outcomes will improve management of coastal biodiversity through a multi-state collaboration of managers, marine ecologists, population geneticists and taxonomists. Sites most needed within marine protected area (MPA) networks for maintaining resilience of populations across seascapes will be identified, including sites with exceptional endemism or key roles in dispersal of larvae. The ecological efficacy of the temperate Australian MPA network will be assessed through analysis of long-term ecological datasets and further development of a novel 'remote sensing' methodology, whereby surveys are undertaken by volunteer divers across much greater spatial and temporal scales than could be studied by dedicated scientific dive teams.Read moreRead less
A stitch in time: evidence-based strategy to keep platypus from extinction. This project aims to assess the status of the iconic platypus, identified as ‘near-threatened’ in 2014. The project’s multidisciplinary approach plans to compare regulated and unregulated rivers to investigate metapopulation structure (via physical and genetic tagging), current condition and future adaptability of the species, as well as other threats and habitat quality. The project also links vulnerability of platypus ....A stitch in time: evidence-based strategy to keep platypus from extinction. This project aims to assess the status of the iconic platypus, identified as ‘near-threatened’ in 2014. The project’s multidisciplinary approach plans to compare regulated and unregulated rivers to investigate metapopulation structure (via physical and genetic tagging), current condition and future adaptability of the species, as well as other threats and habitat quality. The project also links vulnerability of platypus populations to conservation actions that reduce extinction risk, through rigorous decision analyses. It is anticipated that the project will deliver implementable conservation actions at relevant scales.Read moreRead less
Natural selection and the Tasmanian devil. This project aims to explain evolution of immune capabilities in response to disease threats in the wild by assessing the immune adaptive capabilities of Tasmanian devils in response to facial tumour disease. It plans to determine how the expression of immune genes differs between wild and captive populations. The project will combine immunology, epidemiology and evolutionary biology, to understand the role of host genetic and phenotypic adaptations to ....Natural selection and the Tasmanian devil. This project aims to explain evolution of immune capabilities in response to disease threats in the wild by assessing the immune adaptive capabilities of Tasmanian devils in response to facial tumour disease. It plans to determine how the expression of immune genes differs between wild and captive populations. The project will combine immunology, epidemiology and evolutionary biology, to understand the role of host genetic and phenotypic adaptations to disease threats. The project will assist in the development of diagnostic tools for managing this and other threatened species and for screening disease resistance markers across wild and captive insurance populations.Read moreRead less