I am a clinician-scientist and endocrinologist most interested in clinical problems associated with bone, in particular the highly heritable disease of osteoporosis. I hope by studying genetic determinants of bone mass to determine the key genes involved, with the long term aim of informing the development of novel therapies for this common, painful and disabling disease.
Understanding Sperm Motility For Infertility And Contraceptive Purposes
Funder
National Health and Medical Research Council
Funding Amount
$451,716.00
Summary
Male infertility is a significant clinical problem affecting one in twenty Australian men. The most common feature associated with this condition is defects in sperm motility. Regulation of sperm motility occurs through the epididymis and upon ejaculation. This study will examine how two kinases, essential for flagella bending, regulate sperm motility. Through the tools developed, we will investigate further defectives in infertile individuals with impaired sperm motility.