Spectroscopy of Complex Fluids in Flow. Complex fluids are composed of polymers and nano-particles in solution. Under flow these fluids may undergo dramatic molecular and nano-particle orientational and spatial ordering that give rise to a fascinating range of rheological behaviour. This project will use state of the art fluorescence spectroscopy which is able to resolve the orientation of single molecules combined with novel rheo-optic methods to characterise flow induced ordering in these flui ....Spectroscopy of Complex Fluids in Flow. Complex fluids are composed of polymers and nano-particles in solution. Under flow these fluids may undergo dramatic molecular and nano-particle orientational and spatial ordering that give rise to a fascinating range of rheological behaviour. This project will use state of the art fluorescence spectroscopy which is able to resolve the orientation of single molecules combined with novel rheo-optic methods to characterise flow induced ordering in these fluids. The flow induced orientation, spatial distribution and nano-particle/macromolecule interactions will be quantified. Theoretical deficiencies in describing complex fluid flow will be reconciled. The experimental insight gained will be exploited to produce novel molecularly ordered materials.
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Fluidised bed nanoparticle reactors for gas-solid catalytic reactions. This is a "frontier technologies" (nanotechnology) project and promises to open up new opportunities for exciting development in molecular engineering. Catalytic gas-solid reactions are among the most important reactions in chemical industry and energy industry. The novel fluidised bed nanoparticle catalytic reactor is expected to have many important advantages over the conventional porous supported catalyst system. These rea ....Fluidised bed nanoparticle reactors for gas-solid catalytic reactions. This is a "frontier technologies" (nanotechnology) project and promises to open up new opportunities for exciting development in molecular engineering. Catalytic gas-solid reactions are among the most important reactions in chemical industry and energy industry. The novel fluidised bed nanoparticle catalytic reactor is expected to have many important advantages over the conventional porous supported catalyst system. These reactors promise to minimise the waste product generation from chemical and energy industries and so offer great benefit for the environment. Young researchers involved in the project will be equipped with knowledge at the forefront of nanotechnology, enabling them to contribute to Australia's new, high technology future.Read moreRead less
Magnetically controlled drug release from tissue scaffolds for the treatment of acute burns. Severe skin burns are frequently associated with functionally disabling scarring and the risk of death. New magnetically activated wound seals for the treatment of acute burns will be developed that reduce the need for frequent painful dressing changes and hence facilitate rapid healing with a significantly reduced chance of scarring.
The Mechanics of Nanoscale Devices. Australian developments in biosensing, medical diagnostics, clean energy, communication and security technologies, are rapidly growing due to our mounting capacity in nanoscale fabrication. Vital for evolution of next-generation nanodevices is an understanding of how mechanical processes operate at such small scales. This application will contribute to this scientific knowledge base. This will in turn assist Australian industries to progress these applications ....The Mechanics of Nanoscale Devices. Australian developments in biosensing, medical diagnostics, clean energy, communication and security technologies, are rapidly growing due to our mounting capacity in nanoscale fabrication. Vital for evolution of next-generation nanodevices is an understanding of how mechanical processes operate at such small scales. This application will contribute to this scientific knowledge base. This will in turn assist Australian industries to progress these applications and devices, leading to economic, social and technological gains for the Australian community.Read moreRead less
Opto-Microfluidics: A Rapid and Sensitive Platform for Biological Diagnostics. One in four people above 25 years suffer from diabetes-related diseases in Australia, with an associated economic cost exceeding $3 billion a year. A microdevice for continuous glucose monitoring would help patients to manage the disease, leading to huge individual, clinical and societal benefits. Life expectancy is expected to increase along with quality of life. Integration of the microdevice with insulin delivery w ....Opto-Microfluidics: A Rapid and Sensitive Platform for Biological Diagnostics. One in four people above 25 years suffer from diabetes-related diseases in Australia, with an associated economic cost exceeding $3 billion a year. A microdevice for continuous glucose monitoring would help patients to manage the disease, leading to huge individual, clinical and societal benefits. Life expectancy is expected to increase along with quality of life. Integration of the microdevice with insulin delivery would realise an 'artificial pancreas', revolutionising the management and treatment of the disease. The technology will also provide a platform for other point-of-care medical diagnostic devices, which will allow early participation in this emerging market and cement Australia's position in bionanotechnology.Read moreRead less
Lattice Boltzmann method based simulation of complex microchannels and mixing at micro-scales. The proposed study explores fundamental aspects of microfluidics using new tools, which will enhance the country's database of knowledge. It will lead to the development of a low-cost versatile software package, an important tool for solving microfluidics problems of interest to industries and academics, and will facilitate development and optimization of future microdevices. Further, it will improve A ....Lattice Boltzmann method based simulation of complex microchannels and mixing at micro-scales. The proposed study explores fundamental aspects of microfluidics using new tools, which will enhance the country's database of knowledge. It will lead to the development of a low-cost versatile software package, an important tool for solving microfluidics problems of interest to industries and academics, and will facilitate development and optimization of future microdevices. Further, it will improve Australia's competitiveness in the areas of LBM and MEMS both of which are new techniques with promising applications in their respective areas. The project falls under the National Research Priorities areas of Breakthrough Science and Frontier Technology. The potential applications of the technology encompass several key areas.Read moreRead less
Aerodynamic enhancement of the capture of fine particle emissions and gaseous pollutants by sorbents. Fine particulate emissions alone, and just within Australia's four largest cities, are estimated to be responsible for some 1600 deaths annually, and are a leading cause of asthma and other lung disease. Hence the economic and social benefits of greatly reducing fine particulate emissions is enormous. Similar benefits can be expected to arise from the enhanced capture of SOx, NOx and heavy metal ....Aerodynamic enhancement of the capture of fine particle emissions and gaseous pollutants by sorbents. Fine particulate emissions alone, and just within Australia's four largest cities, are estimated to be responsible for some 1600 deaths annually, and are a leading cause of asthma and other lung disease. Hence the economic and social benefits of greatly reducing fine particulate emissions is enormous. Similar benefits can be expected to arise from the enhanced capture of SOx, NOx and heavy metals. Many of these pollutants also contribute to the greenhouse effect, so the international exploitation of the technology will also help to mitigate climate change. Should suitable sorbents be developed for CO2 capture, the technology will also enhance carbon capture and storage.Read moreRead less
Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design stand ....Micro Process Plants - Non-Newtonian flow and particle synthesis in confined geometries. Understanding the flow behaviour of well characterised non-Newtonian fluids within microfluidic and nanofluidic devices is of vital importance to development of novel high-value added services, products and devices within Australia's burgeoning biotechnology, environmental technology, communications and information technology industries. The outcomes of this project will provide new 'systematic' design standards for microdevice manufacture for these industries, ultimately leading to the creation of new, exciting avenues for tailoring novel biotechnology and 'point-of-care' products for Australia.Read moreRead less
Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (b ....Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (biochem)security analysis devices. Hence this project is an investment in enabling technologies to benefit Australia's growing biotech, pharmaceutical and micro/nanotechnology sectors. Tangible community benefits (e.g., in improved diagnostic technologies, pharmaceuticals) will result.Read moreRead less
DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to und ....DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to understand and quantify factors influencing droplet deformation. Coupling non-Newtonian characteristics with microfluidic geometries will allow the continuous manufacture of micro-particles of specified size and shape for existing and new applications, and will provide guidance for further extending the process to nano-particle manufacture.Read moreRead less