Towards sustainable co-management of groundwater in the Beetaloo region, NT. This project aims to improve understanding of connections between groundwater, climate, surface water and Indigenous cultural values, in a region of major resource development in the Northern Territory. It will use a novel, inter-disciplinary approach, involving remote sensing of climate-water-landscape interactions, documenting Indigenous water knowledge, environmental isotope monitoring, and water policy analysis. The ....Towards sustainable co-management of groundwater in the Beetaloo region, NT. This project aims to improve understanding of connections between groundwater, climate, surface water and Indigenous cultural values, in a region of major resource development in the Northern Territory. It will use a novel, inter-disciplinary approach, involving remote sensing of climate-water-landscape interactions, documenting Indigenous water knowledge, environmental isotope monitoring, and water policy analysis. The project expects to generate enhanced understanding of hydrological processes, and associated Indigenous cultural values. This is anticipated to improve capacity to analyse risks to groundwater-dependent values, and foster greater Indigenous participation in water planning and monitoring, benefiting multiple stakeholders.Read moreRead less
Better water management through more focus on ecological and social sciences. Current water resources management, focusing on gains of economic efficiency in the short term under the assumption of steady-state conditions, has generally failed to respond to both catchment environmental degradation and to the increasing complexity of human–environment interactions. This project will develop a new approach to water resources management by relating management practices based on ecological understand ....Better water management through more focus on ecological and social sciences. Current water resources management, focusing on gains of economic efficiency in the short term under the assumption of steady-state conditions, has generally failed to respond to both catchment environmental degradation and to the increasing complexity of human–environment interactions. This project will develop a new approach to water resources management by relating management practices based on ecological understanding to the social mechanisms behind these practices at water catchments. It will improve the predictability and precision of water resources management and increase our ability to maintain our options for a sustainable future. This will have a profound effect on catchment sustainability, a globally significant problem.Read moreRead less
A robust integrated streamflow forecasting framework for Australian water information and management agencies. This project aims to deliver an accurate and reliable seasonal streamflow forecasting system for Australian water users by developing a flexible rainfall-runoff modelling approach integrated into a Bayesian inference and prediction framework. These scientific developments aim to significantly advance the operational capabilities of the Australian Bureau of Meteorology to deliver robust ....A robust integrated streamflow forecasting framework for Australian water information and management agencies. This project aims to deliver an accurate and reliable seasonal streamflow forecasting system for Australian water users by developing a flexible rainfall-runoff modelling approach integrated into a Bayesian inference and prediction framework. These scientific developments aim to significantly advance the operational capabilities of the Australian Bureau of Meteorology to deliver robust streamflow forecasts to water agencies such as South East Queensland Water and others across Australia. Accurate predictions of future water flows are of tremendous value to urban and rural Australian communities whose economic prosperity, water security and social well-being depend on reliable estimates of water availability.Read moreRead less
Physical factors affecting deposition of combustion submicrometer particles in the human lung. Particles generated from combustion sources have a profound effect on human health, yet there is lack of scientific understanding of the role of different physical mechanisms on particle deposition in the lung. This program will advance scientific knowledge in this field through multidisciplinary efforts of a team from QUT and the University of Salzburg, Austria. It aims at quantification of particle d ....Physical factors affecting deposition of combustion submicrometer particles in the human lung. Particles generated from combustion sources have a profound effect on human health, yet there is lack of scientific understanding of the role of different physical mechanisms on particle deposition in the lung. This program will advance scientific knowledge in this field through multidisciplinary efforts of a team from QUT and the University of Salzburg, Austria. It aims at quantification of particle deposition in human lung through experimental studies and advanced modelling. The program will enhance and strengthen the existing collaboration between the universities and its outcome will be of significance in the vital area of human health and risk assessment.Read moreRead less
Advanced Combustion Modelling for Scramjets and Rotating Detonation Engines. This project will develop new fundamental knowledge and engineering models underpinning air-breathing high speed propulsion engines employing complex hydrocarbon fuels. Extensive data and new physical understanding will be garnered through analysis of direct numerical simulations of supersonic reacting mixing layers including impinging shock waves. That data will be employed to isolate, test and develop computationally ....Advanced Combustion Modelling for Scramjets and Rotating Detonation Engines. This project will develop new fundamental knowledge and engineering models underpinning air-breathing high speed propulsion engines employing complex hydrocarbon fuels. Extensive data and new physical understanding will be garnered through analysis of direct numerical simulations of supersonic reacting mixing layers including impinging shock waves. That data will be employed to isolate, test and develop computationally efficient engineering models that are accurate and efficient for high speed combustion in rotating detonation engines and scramjets. Expected outcomes are knowledge and tools needed to develop practical and effective supersonic propulsion engines for access to space, defence and high speed point-to-point flight.
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Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expecte ....Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expected to deliver new experimental data on novel surface materials exposed to a hypersonic flow environment and computer models that can simulate their cooling effect. This investigation will contribute towards enabling technologies for sustained hypersonic flight by overcoming critical head load limitations.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Optimising artificial reef structures for nature-based coastal protection . This project aims to develop a novel framework for predicting how artificial reef structures can be optimally designed to protect coastlines from erosion and flooding. It will develop new theory and models to quantify how waves interact with complex reef structures to reduce wave heights and extreme water levels at the shoreline. Expected outcomes include new practical tools and design guidelines that can be adopted by c ....Optimising artificial reef structures for nature-based coastal protection . This project aims to develop a novel framework for predicting how artificial reef structures can be optimally designed to protect coastlines from erosion and flooding. It will develop new theory and models to quantify how waves interact with complex reef structures to reduce wave heights and extreme water levels at the shoreline. Expected outcomes include new practical tools and design guidelines that can be adopted by coastal engineers and managers to maximise coastal protection by reefs. This will boost Australia’s capacity to protect populations and critical infrastructure from coastal hazards and support Australian industries to lead the international development of innovative nature-based coastal protection strategies.Read moreRead less
Understanding the differentiation of the endocardium. The project aims to understand the genetic regulation of endocardial development. The heart is essential for survival, its beat the indicator of life. The endocardium, the heart’s inner lining, is required for signalling during heart development and is a major component of the valves, septa and trabeculae. Despite its indispensable role, little is known about how it forms or develops. This project integrates two complementary approaches that ....Understanding the differentiation of the endocardium. The project aims to understand the genetic regulation of endocardial development. The heart is essential for survival, its beat the indicator of life. The endocardium, the heart’s inner lining, is required for signalling during heart development and is a major component of the valves, septa and trabeculae. Despite its indispensable role, little is known about how it forms or develops. This project integrates two complementary approaches that have identified the earliest marker of endocardial differentiation and devised the method to make endocardium from stem cells. Knowledge from this work will inform future research into growing and regenerating damaged tissue.Read moreRead less
Kruppel-like factors and the methylome. This project aims to test the hypothesis that the KLF/SP family of transcription factors work in part via dynamic interactions with methylated cytosine nucleotides in DNA. This is fundamental to their function as pioneer factors in reprograming and their ability to co-ordinate differentiation and organogenesis. Conversely, dynamic changes in methylation status engage or disengage new regulatory elements in the genome via recruitment of KLF/SP family protei ....Kruppel-like factors and the methylome. This project aims to test the hypothesis that the KLF/SP family of transcription factors work in part via dynamic interactions with methylated cytosine nucleotides in DNA. This is fundamental to their function as pioneer factors in reprograming and their ability to co-ordinate differentiation and organogenesis. Conversely, dynamic changes in methylation status engage or disengage new regulatory elements in the genome via recruitment of KLF/SP family proteins as specific effectors. This project will address a new paradigm in genetics that is likely to underpin development.Read moreRead less