A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Mitigating the risk of cyanobacterial blooms in wastewater ponds. Cyanobacterial blooms in wastewater treatment plants impact on effluent quality and the utility of recycled water, posing a significant risk to the economy, the environment and public health. To understand the causes of cyanobacterial blooms in pond-based wastewater treatment plants and the risk they pose, this project will use the latest molecular techniques to examine how the microbial communities within these systems interact w ....Mitigating the risk of cyanobacterial blooms in wastewater ponds. Cyanobacterial blooms in wastewater treatment plants impact on effluent quality and the utility of recycled water, posing a significant risk to the economy, the environment and public health. To understand the causes of cyanobacterial blooms in pond-based wastewater treatment plants and the risk they pose, this project will use the latest molecular techniques to examine how the microbial communities within these systems interact with each other and their surrounding environment to form blooms and produce toxins and other harmful metabolites. Such knowledge will inform risk assessment and provide strategies for the mitigation of future bloom events, improving the security of our increasingly valuable recycled water resources.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
Buffering the ecosystem impact of invasive cane toads. This project aims to address the devastating ecological problems caused by invasive species, by developing a novel approach that does not rely upon eradicating the invader through training vulnerable native predators not to eat toxic cane toads. Expected outcomes of this project include building a broad coalition of conservation-focused groups, from private land-owners and local businesses through to Indigenous groups and government and non- ....Buffering the ecosystem impact of invasive cane toads. This project aims to address the devastating ecological problems caused by invasive species, by developing a novel approach that does not rely upon eradicating the invader through training vulnerable native predators not to eat toxic cane toads. Expected outcomes of this project include building a broad coalition of conservation-focused groups, from private land-owners and local businesses through to Indigenous groups and government and non-government agencies across the entire Kimberley region. It will also result in the evaluation of methods for deployment of taste-aversion at a landscape scale. This should provide significant benefits by conserving vulnerable fauna and building a powerful network within a region of high biodiversity in tropical Australia.Read moreRead less
Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, ....Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, unprecedented in scope and resolution. Outcomes include an open access database to quantify and visualise intra-urban air pollution and human exposure and develop air quality maps and smoke pollution management tools. It is expected to advance the evidence-based management of air as a resource, increasing economic prosperity and enhancing human health and quality of life.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100093
Funder
Australian Research Council
Funding Amount
$510,000.00
Summary
High-throughput technology targeting antimicrobial resistance in animals. This project aims to establish reference laboratories as biobanks for resistant isolate collections from veterinary diagnostic laboratories / surveillance programmes and a national research network to mitigate antimicrobial resistance in animals. Antimicrobial resistance in zoonotic/foodborne pathogens and livestock commensals is a global issue. This project will use mass-spectroscopy biotypers, information management soft ....High-throughput technology targeting antimicrobial resistance in animals. This project aims to establish reference laboratories as biobanks for resistant isolate collections from veterinary diagnostic laboratories / surveillance programmes and a national research network to mitigate antimicrobial resistance in animals. Antimicrobial resistance in zoonotic/foodborne pathogens and livestock commensals is a global issue. This project will use mass-spectroscopy biotypers, information management software, robotic liquid handling and a research dairy to develop high-throughput screening technologies to rapidly determine major animal species’ resistance status, and research anti-infectives and vaccines for livestock diseases. This will improve the health and production of Australian livestock, leading to greater market access for high quality products.Read moreRead less
Convex optimisation for control, signal processing and communication systems. Renewable control of complex systems, signal processing, telecommunication and in general any industries interested in these applications stand to benefit from our research. In particular, the automotive and defence industries stand to benefit from the nonlinear control design aspect of the proposed project outcomes. The
telecommunications industries, on the other hand, benefit from the signal processing and communicat ....Convex optimisation for control, signal processing and communication systems. Renewable control of complex systems, signal processing, telecommunication and in general any industries interested in these applications stand to benefit from our research. In particular, the automotive and defence industries stand to benefit from the nonlinear control design aspect of the proposed project outcomes. The
telecommunications industries, on the other hand, benefit from the signal processing and communications aspects. We also build a core expertise in optimisation and its applications in Australia by training PhD students and Postdoctoral researchers. The research collaborations will cement and maintain the international linkages which will improve applied research in AustraliaRead moreRead less
Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
Improving Sexual Health In Men With Prostate Cancer: Randomised Controlled Trial Of Exercise And Psychosexual Therapies
Funder
National Health and Medical Research Council
Funding Amount
$583,416.00
Summary
Sexual dysfunction is one of the most common and distressing side effects of prostate cancer. Despite being a critical survivorship care issue, there is a clear gap in knowledge surrounding the optimal treatment of sexual dysfunction in men with prostate cancer. This project examines whether exercise aids in the management of sexual dysfunction and explores if an integrated treatment model incorporating pharmacological, exercise and psychosexual therapies maximises improvement in sexual health.
Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or refl ....Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or reflect damaging waves under severe conditions. Under normal conditions, enough wave energy to sustain environmental processes would pass through. Sales of electricity would help to pay back the capital cost. Outcomes would include reduced coastal-erosion costs and a low-intermittency energy supply.Read moreRead less