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Treatment Of Asymptomatic Candidiasis In Pregnant Women For The Prevention Of Preterm Birth: A Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,120,373.00
Summary
Being born too early is a leading cause of perinatal death and morbidity. This trial seeks to determine whether screening for and treating candidiasis in pregnancy reduces the risk of this serious health problem. The trial will discover whether a simple treatment in pregnancy can reduce preterm birth. If positive, the results will be relevant to the management of every pregnancy.
The Effects Of Different Alcohol Pricing Policies On Alcohol Consumption, Health, Social And Economic Outcomes, And Health Inequality In Australia
Funder
National Health and Medical Research Council
Funding Amount
$276,738.00
Summary
This project will examine the effects, effectiveness and cost-benefits of alcohol pricing policy initiatives in reducing risky drinking, health and social harms and health inequalities among priority populations in Australia. This project will provide key research evidence to cut through current policy debates and will point towards the most effective potential options for alcohol tax reform.
Air Pollution And Mortality And Morbidity In Adult Australians (APMMA Study): A Large Population Based Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$1,041,410.00
Summary
This study will investigate the link between respiratory and cardiovascular disease and mortality and exposure to long-term air pollution. We will use cutting edge methods to assign neighbourhood air pollution levels to a large cohort of NSW adults (n>265,000) previously recruited in the 45 and Up Study. The study results will be of utmost importance in setting outdoor air pollution standards and informing cost benefit analyses of air pollution control strategies.
An Empirical Framework For Assessing Mortality And Morbidity In People With Psychotic Disorders: A 7-year Prospective And 10-year Retrospective Follow-up Of 2075 Participants In The Survey Of High Impact Psychosis (SHIP) Using Linked Registers
Funder
National Health and Medical Research Council
Funding Amount
$751,876.00
Summary
Our study is designed to fill a knowledge gap on mortality and morbidity in people with a psychotic disorder. It will: 1. Estimate rates of 7-year mortality and morbidity in people with a psychotic disorder. 2. Examine the impact of sets of risk factors on mortality and morbidity. 3. Develop predictive risk equations for CVD for use with people with psychotic disorders. 4. Calculate the economic burden of severe and acute physical morbidity in addition to mental health impacts.?
Preventing Adverse Effects Of Matrix Metalloproteinases In Diabetic Wound Healing
Funder
National Health and Medical Research Council
Funding Amount
$387,784.00
Summary
Treatment of diabetic foot ulcers presents a significant challenge to diabetic patients and the health care system. Despite concerted treatment, many ulcers do not heal and it is this failure to heal which eventually leads to deep-seated infection and amputation. For these reasons development of new therapeutic strategies to improve wound healing in diabetes is of critical importance. In this study we investigate the role of MMPs in particular MMP-9 in diabetic wounds and examine whether MMP inh ....Treatment of diabetic foot ulcers presents a significant challenge to diabetic patients and the health care system. Despite concerted treatment, many ulcers do not heal and it is this failure to heal which eventually leads to deep-seated infection and amputation. For these reasons development of new therapeutic strategies to improve wound healing in diabetes is of critical importance. In this study we investigate the role of MMPs in particular MMP-9 in diabetic wounds and examine whether MMP inhibition will improve wound healing in diabetes.Read moreRead less
Health And Social Consequences Of Child Abuse And Neglect: An Analysis Using South Australian Linked Data
Funder
National Health and Medical Research Council
Funding Amount
$684,447.00
Summary
Child maltreatment can result in a range of poor health, social and economic outcomes. Current surveys tell us little about the size of these impacts for young people especially for those with the worst outcomes—death, homelessness, hospitalisation, incarceration. This study will use data from hospitals, child protection and other services to explore the impacts of maltreatment on young people in SA and related costs to government, to inform policy to improve outcomes for this vulnerable group.
The True Burden Of Nosocomial Staphylococcal Disease: Genomic Markers Of Transmission Of Methicillin-sensitive And –resistant Staphylococcus Aureus
Funder
National Health and Medical Research Council
Funding Amount
$830,092.00
Summary
Staphylococcus aureus is the leading cause of hospital infection, but previous studies have only focused on the 30% caused by resistant strains (MRSA). We will trace the spread of all Staphylococcus strains in hospitals using DNA fingerprinting. This will enable us to determine why patients catch this infection, permitting interventions to reduce hospital infection. We will also examine the genomes of these bacteria to look for markers of transmission and adaptation to the hospital environment.
Efficacy And Safety Of Omega-3 DHA Supplementation In Preterm Infants: Childhood Follow-up Of The N3RO Trial.
Funder
National Health and Medical Research Council
Funding Amount
$713,218.00
Summary
Giving babies born 3 to 4 months prematurely the omega-3 DHA has been thought to improve their mental development. But we don’t yet know if this is indeed so. In this follow-up study, we will be able to find out the important longer-term effects at 5-years of age of extra DHA in the first months of life by assessing the children’s mental development.
‘Defying The Odds’: Exploring The Impact Of Perinatal Outcomes, Maternal Social And Health Outcomes And Level Of Culturally Appropriate Service Availability On The Health Of Western Australian Aboriginal Infants And Children
Funder
National Health and Medical Research Council
Funding Amount
$659,356.00
Summary
A healthy start to life is essential for life-long health. Currently, Aboriginal children have greater rates of death and hospitalisation than other Australians. This study will determine individual, community and service-related risk and protective factors for health outcomes among Aboriginal children (0-5yrs) using whole-of-population linked health data from multigenerational Aboriginal families in WA. Findings will support effective service development to help those at-risk ‘defy the odds’.
A Cluster RCT Of A Novel Psychological Intervention To Reduce Depression Among At-risk Older Adults Transitioning To Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$893,152.00
Summary
Depression is common in aged care facilities, with many older adults finding the transition extremely difficult. We have developed a simple intervention to help new residents, including those with dementia, to adjust to life in aged care. This program focuses on key aspects of psychological wellbeing, and is designed for widespread use in aged care. We will evaluate the intervention to determine if it is superior to current care approaches in reducing depression and improving quality of life.