I am a consultant psychiatrist and clinical researcher. Over the last 15 years I have been trying to detect people at risk of development of schizophrenia and other psychotic disorders by the prospective identification of the prodromal phase of these diso
The applicant is a clinical psychologist. Research focuses on developing, evaluating and disseminating psychological interventions for co-existing mental health (e.g. schizophrenia, depression, anxiety) and alcohol and other drug problems (e.g. alcohol, c
A Healthy Start To Life, Preventative Healthcare, Strengthening Australias Social Economic Fabric
Funder
National Health and Medical Research Council
Funding Amount
$4,000,000.00
Summary
The aim is to make a major contribution to the reduction of non-fatal disease burden internationally due to mental disorders and related alcohol and substance abuse through population-based research and development health strategies. Current estimates of avertable burden for mental disorders suggest that while 40% of the burden can be reduced by optimal implementation of currently available interventions another 60% will remain unavertable without new knowledge. That new knowledge includes not o ....The aim is to make a major contribution to the reduction of non-fatal disease burden internationally due to mental disorders and related alcohol and substance abuse through population-based research and development health strategies. Current estimates of avertable burden for mental disorders suggest that while 40% of the burden can be reduced by optimal implementation of currently available interventions another 60% will remain unavertable without new knowledge. That new knowledge includes not only that derived from novel or basic neurosciences but also clear determination as to whether currently proposed early intervention paradigms for young persons with mental disorders deliver sustained benefits. To ensure the maximum benefit for persons with mental disorders, Professor Hickie needs to engage directly in two major streams of activity. The first (75% of research effort) lies in maximising the chances that the health services and other population health activities that he has championed so actively over the last decade are now utilised to both advance knowledge as well as make a much greater contribution to actual reduction in illness burden. The second (25% of research effort) lies in maximising the specific international skills collected within the BMRI and distributed more widely in its local, national and international research networks. Mental Health Research desperately needs new basic science, translational and clinical knowledge and the combination of an Australian Fellowship and these networks would provide the environment for maximising the chances of achieving such real knowledge breakthroughsRead moreRead less
I am an immunochemist-cell biologist investigating the involvement endosomes and lysosomes in different disease states. A primary focus has been on the group of diseases called lysosomal storage disorders where early diagnostic and effective treatment strategies have been and continue to be developed. Due to the multi-functionality of endosomes and lysosomes, these critical organelles are also involved in the pathology caused by other major diseases like bacterial infection and cancer, and this ....I am an immunochemist-cell biologist investigating the involvement endosomes and lysosomes in different disease states. A primary focus has been on the group of diseases called lysosomal storage disorders where early diagnostic and effective treatment strategies have been and continue to be developed. Due to the multi-functionality of endosomes and lysosomes, these critical organelles are also involved in the pathology caused by other major diseases like bacterial infection and cancer, and this is being actively investigated.Read moreRead less
I am a cell-development biologist using genetic approaches in the model vertebrate zebrafish to study the regulation of myeloid blood cell development. My laboratory haematology research is in basic science and biology of haemopoiesism but is closely rel