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Use of Distichlis spicata for sustainable forage production on saline land to manage dryland salinity. Sustainable and productive use of salt-affected lands is a priority for many farmers. This project aims to develop management strategies that optimise yield, water use and nutritive value of Distichlis spicata (a salt-tolerant grass) forage on salinised lands, and to understand how this forage species affects the salt cycle, water use and fertility improvement of saline soils.
Evaluating the role of buffer strips in reducing soil erosion and sediment delivery to water bodies. The role of vegetative buffer strips in reducing soil erosion and sediment delivery to water bodies is well established, but the physical processes and their interactions involved are not well understood. These hydraulic, sediment/chemical transport processes will be modelled from physical principles, recognising that the multi-size characteristics of soil plays a vital role in buffer strip effec ....Evaluating the role of buffer strips in reducing soil erosion and sediment delivery to water bodies. The role of vegetative buffer strips in reducing soil erosion and sediment delivery to water bodies is well established, but the physical processes and their interactions involved are not well understood. These hydraulic, sediment/chemical transport processes will be modelled from physical principles, recognising that the multi-size characteristics of soil plays a vital role in buffer strip effectiveness. This model will be validated using new and existing data sources, including both controlled experiments and field data obtained in Australia and overseas. A user friendly version of the model will be developed for farm managers and advisory services as a design tool.Read moreRead less
Modelling soil formation in the landscape. Soil is a complex system composed of a set of interconnected physical, chemical and biological factors that function as a whole. Soil system is a key part of natural ecosystems that is significantly affected by land management. This project aims to create a new quantitative model for soil formation in the landscape. This project will investigate whether the soil variability is a result of the soil being a complex system. The outcome of the model will en ....Modelling soil formation in the landscape. Soil is a complex system composed of a set of interconnected physical, chemical and biological factors that function as a whole. Soil system is a key part of natural ecosystems that is significantly affected by land management. This project aims to create a new quantitative model for soil formation in the landscape. This project will investigate whether the soil variability is a result of the soil being a complex system. The outcome of the model will enable us to reconstruct the history of soil profile development in the landscape and help us understand how soil forms and landscape evolves with time.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347955
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
A Cell Sorter Facility for Neuroscience and Related Biotechnology. Neuroscience is entering an era of accelerated discovery in which Queensland neuroscientists can excel if they gain leadership in key technologies. One critical technology is the ability to obtain specific cell populations from various parts of the nervous system in sufficient quantity and purity to enable their accurate examination by gene array, proteomics and physiological techniques. The aim is to establish the world's first ....A Cell Sorter Facility for Neuroscience and Related Biotechnology. Neuroscience is entering an era of accelerated discovery in which Queensland neuroscientists can excel if they gain leadership in key technologies. One critical technology is the ability to obtain specific cell populations from various parts of the nervous system in sufficient quantity and purity to enable their accurate examination by gene array, proteomics and physiological techniques. The aim is to establish the world's first cell-sorting facility dedicated to the production of nerve cells suitable for molecular characterization and screening, providing the basis for identifying key molecules regulating brain function, ageing and repair of great importance to the biotechnology/pharmaceutical industry.Read moreRead less
Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
The molecular mechanism of retromer and sorting nexin function in endosomal membrane trafficking. The proposed research represents breakthrough science that will lead to a fundamental understanding at the molecular level of the structure and assembly of the retromer complex and how it regulates sorting of receptors in the endosomal system. It will provide excellent research training for top graduate students and post-doctoral scientists in multidisciplinary methods that constitute state-of the- ....The molecular mechanism of retromer and sorting nexin function in endosomal membrane trafficking. The proposed research represents breakthrough science that will lead to a fundamental understanding at the molecular level of the structure and assembly of the retromer complex and how it regulates sorting of receptors in the endosomal system. It will provide excellent research training for top graduate students and post-doctoral scientists in multidisciplinary methods that constitute state-of the-art structural and molecular cell biology research. By addressing an area of great interest internationally the project will have the capacity to increase Australia's knowledge base and strengthen it's reputation for research excellence.Read moreRead less
Endosomal Protein Transport: From Molecular Structures to Biological Function. Intracellular transport of biomolecules through the endosomal organelle is critical for normal cellular processes such as signalling, homoeostasis and development. Defects in this fundamental process and subversion of it by bacterial and viral pathogens also lead to many different human diseases. This project will build on Australia's strong programme of structural and cellular biology research to develop key insights ....Endosomal Protein Transport: From Molecular Structures to Biological Function. Intracellular transport of biomolecules through the endosomal organelle is critical for normal cellular processes such as signalling, homoeostasis and development. Defects in this fundamental process and subversion of it by bacterial and viral pathogens also lead to many different human diseases. This project will build on Australia's strong programme of structural and cellular biology research to develop key insights into endosomal trafficking at the molecular level. Outcomes from this work will place Australia at the forefront of international efforts to understand this essential biological process and will have important implications for future design of pharmaceuticals.Read moreRead less