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2026 ARDC Annual Survey is now open!

The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your interaction with the ARDC and use of our national research infrastructure and services. The survey will take approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure services including Reasearch Link Australia.

We will use the information you provide to improve the national research infrastructure and services we deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS) program.

Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.

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Research Topic : protein degradation
Status : Active
Country : Australia
Australian State/Territory : NSW
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Biochemistry and cell biology (3)
Land Capability and Soil Degradation (3)
Protein trafficking (3)
Soil Sciences (3)
Carbon Sequestration Science (2)
Cell development proliferation and death (2)
Biologically active molecules (1)
Cellular interactions (incl. adhesion matrix cell wall) (1)
Mechanobiology (1)
Proteomics and intermolecular interactions (excl. medical proteomics) (1)
Soil Biology (1)
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Farmland, Arable Cropland and Permanent Cropland Soils (3)
Expanding Knowledge In the Biological Sciences (2)
Sparseland, Permanent Grassland and Arid Zone Soils (2)
Ecosystem Assessment and Management of Farmland, Arable Cropland and Permanent Cropland Environments (1)
Expanding Knowledge In the Biomedical and Clinical Sciences (1)
Expanding Knowledge In the Chemical Sciences (1)
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Australian Research Council (6)
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  • Researchers (48)
  • Funded Activities (6)
  • Organisations (16)
  • Active Funded Activity

    Discovery Projects - Grant ID: DP190103005

    Funder
    Australian Research Council
    Funding Amount
    $450,000.00
    Summary
    Synergising pedodiversity and biodiversity to secure soil functionality. This project aims to understand the coupling between soil physical, chemical and biological diversity at a range of scales and land uses across New South Wales and its relationship with soil functioning. Soil diversity with its coupled biodiversity is crucial for conservation of sustainable ecosystems. Soil diversity varies on a continuum from microbial habitats to elds, catchments and regions. This project will enhance ou .... Synergising pedodiversity and biodiversity to secure soil functionality. This project aims to understand the coupling between soil physical, chemical and biological diversity at a range of scales and land uses across New South Wales and its relationship with soil functioning. Soil diversity with its coupled biodiversity is crucial for conservation of sustainable ecosystems. Soil diversity varies on a continuum from microbial habitats to elds, catchments and regions. This project will enhance our ability to understand the drivers of soil change through time, critical for minimising loss of biodiversity, achieving food and soil security and inferring effects of climate change.
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    Active Funded Activity

    Australian Laureate Fellowships - Grant ID: FL210100054

    Funder
    Australian Research Council
    Funding Amount
    $3,277,650.00
    Summary
    A calculable approach to securing Australia's soil. Much of our productive land is currently degraded, severely impacting the ability of soils to contribute to planetary health. The aim of this program is to deliver a comprehensive systematic soil monitoring system within a world-first soil security framework. The research will create a detailed reference of the Australian landscape to elucidate impacts on our soil cover. Soil security indicators will be created from which ameliorative actions c .... A calculable approach to securing Australia's soil. Much of our productive land is currently degraded, severely impacting the ability of soils to contribute to planetary health. The aim of this program is to deliver a comprehensive systematic soil monitoring system within a world-first soil security framework. The research will create a detailed reference of the Australian landscape to elucidate impacts on our soil cover. Soil security indicators will be created from which ameliorative actions can be prioritised, while early warning systems will offer predictive capability around emerging threats to soil condition, feeding into best-management practices for regeneration. Outcomes will see soil secured for future generations and Australia at the forefront of soil assessment and restoration.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP200102542

    Funder
    Australian Research Council
    Funding Amount
    $455,000.00
    Summary
    Forecasting soil conditions. Not knowing where and how soil responds to climate change and human intervention compromises food, water, climate and energy security. Currently there is a lack of soil process knowledge and data infrastructure collectively causing significant uncertainty and risk in the assessments of key threats to soil. The project devises a transformational digital soil model to forecast where and how soil pH and carbon will change in New South Wales. Tested on sites within Au .... Forecasting soil conditions. Not knowing where and how soil responds to climate change and human intervention compromises food, water, climate and energy security. Currently there is a lack of soil process knowledge and data infrastructure collectively causing significant uncertainty and risk in the assessments of key threats to soil. The project devises a transformational digital soil model to forecast where and how soil pH and carbon will change in New South Wales. Tested on sites within Australia, the model will give insight on the drivers of change and will provide a unique analysis of the effect of climate change and land management on the dynamics of soil.
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    Active Funded Activity

    Bioprinting And Advanced Visualisation Of Novel 3D Model Systems.

    Funder
    Australian Research Council
    Funding Amount
    $1,009,078.00
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    Active Funded Activity

    Discovery Projects - Grant ID: DP240100514

    Funder
    Australian Research Council
    Funding Amount
    $1,031,345.00
    Summary
    Chemical staples and chemical probes to dissect dynamins cellular roles. Modulation of protein structure drives cellular function. Dynamin GTPase forms at least two macromolecular structures with different cellular functions. The drivers behind these different structures is unknown. In this project we will leverage our discoveries, and planned enhancements, of chemical biology probes that will modulate dynamin activity by inhibiting at three distinct sites, and one site that stimulates dynamin a .... Chemical staples and chemical probes to dissect dynamins cellular roles. Modulation of protein structure drives cellular function. Dynamin GTPase forms at least two macromolecular structures with different cellular functions. The drivers behind these different structures is unknown. In this project we will leverage our discoveries, and planned enhancements, of chemical biology probes that will modulate dynamin activity by inhibiting at three distinct sites, and one site that stimulates dynamin activity. It is known that Dynamin helices and rings are believed responsible for at least three in cell biological functions: in hormone, neutral and receptor internalisation; cellular mitosis and in actin dynamics. Prior to this work we have lacked the tools to understand the role of shape modulation of protein function.
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    Active Funded Activity

    Discovery Early Career Researcher Award - Grant ID: DE240100707

    Funder
    Australian Research Council
    Funding Amount
    $450,926.00
    Summary
    Towards a molecular fingerprint for human-specific endogenous retroviruses. This project aims to understand how ancient viral sequences resident in the human genome can contribute to cellular processes. Using a novel molecular toolbox that combines affinity-directed proximity labelling mass spectrometry and single molecule microscopy, this project will characterise the cellular fingerprint of a human endogenous retrovirus family HERV-K (HML-2). This fingerprint will comprehensively describe how .... Towards a molecular fingerprint for human-specific endogenous retroviruses. This project aims to understand how ancient viral sequences resident in the human genome can contribute to cellular processes. Using a novel molecular toolbox that combines affinity-directed proximity labelling mass spectrometry and single molecule microscopy, this project will characterise the cellular fingerprint of a human endogenous retrovirus family HERV-K (HML-2). This fingerprint will comprehensively describe how expressed HERV-K loci engage with the homeostasis network in human cells. This will provide significant benefits in the form of new knowledge concerning fundamental aspects of cellular homeostasis, and a state-of-the-art molecular biology toolbox ready to explore quantitatively the role of HERV-K in human health and disease.
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    Showing 1-6 of 6 Funded Activites

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