Recovery and characterization of monooxygenases for biocatalysis and bioremediation through development of novel DNA- and protein-based technology. Australia contains hundreds of sites contaminated with toxic waste and judged to pose significant risk of harm to the public. This project will identify enzymes and organisms capable of remediating such contaminated sites by natural processes. It will also result in training of persons and development of techniques that will contribute to making bi ....Recovery and characterization of monooxygenases for biocatalysis and bioremediation through development of novel DNA- and protein-based technology. Australia contains hundreds of sites contaminated with toxic waste and judged to pose significant risk of harm to the public. This project will identify enzymes and organisms capable of remediating such contaminated sites by natural processes. It will also result in training of persons and development of techniques that will contribute to making bioremediation an environmentally sustainable and cost-effective technology. The environmental proteomics strategy is a frontier technology, expected to have broad applications in health, food science and the environment. Our development of this technology will create a wide range of opportunities for Australian scientists and companies.Read moreRead less
Disulfide Bonds and Protein Folding. This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology ....Disulfide Bonds and Protein Folding. This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology. This work could yield economic benefits in the long-term through patentable outcomes and will benefit the community by producing high impact research papers, providing training to Australians and forging links with renowned international scientists.Read moreRead less
New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R& ....New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R&D company that will lead to development of new techniques for use in biotechnology in Australia and overseas.Read moreRead less
Electronically Conducting Nanofibres and Assemblies. With the use of new techniques that have just emerged in the last two years and are receiving rapidly growing interest throughout the world, this project will bring to Australia a new nanofabrication platform for making a variety of complex nanostructures. Fundamental researches on these complex nanostructures will greatly advance nanoscience. New nanotechnologies will be developed to address some world-wide challenging problems, e.g. energy ....Electronically Conducting Nanofibres and Assemblies. With the use of new techniques that have just emerged in the last two years and are receiving rapidly growing interest throughout the world, this project will bring to Australia a new nanofabrication platform for making a variety of complex nanostructures. Fundamental researches on these complex nanostructures will greatly advance nanoscience. New nanotechnologies will be developed to address some world-wide challenging problems, e.g. energy conversion and storage, chemical/biological sensing and other micro- and nanoelectronic devices. This project will bring both breakthrough science and frontier technologies for building and transforming Australian industries and help place Australia at the forefront of nanotechnology. Read moreRead less
Understanding the Behavior of Single-Walled Carbon Nanotubes in Liquids. The imminent manufacture of Single Walled Carbon Nanotubes (SWNTs) at prices comparable to those of high-performance polymers such as Kevlar, will open up potential applications of SWNTs as high-performance fibres and coatings. A major challenge is the development of scalable processes for producing large objects made of SWNTs. This project, in collaboration with researchers at Rice and Stanford Universities, aims to unders ....Understanding the Behavior of Single-Walled Carbon Nanotubes in Liquids. The imminent manufacture of Single Walled Carbon Nanotubes (SWNTs) at prices comparable to those of high-performance polymers such as Kevlar, will open up potential applications of SWNTs as high-performance fibres and coatings. A major challenge is the development of scalable processes for producing large objects made of SWNTs. This project, in collaboration with researchers at Rice and Stanford Universities, aims to understand the principles that underlie the successful liquid state processing of SWNTs. The novel strategies that arise will cement Australia's position as a leading country for research in nanotechnology, and place it at the forefront of this field, with great potential for economic advantage.Read moreRead less
Predictive Assessment Tool for Beach Conditions Using Video Imaging and Neural Network Analysis. Beaches are vital part of Australian lifestyle and economic development. Monitoring of variable beach conditions is vital for beach safety and for management of storm erosion. The aim of this project is to develop an assessment tool which will permit a rating system of beach conditions both from an environmental as well as a leisure aspect. This tool will be developed into a software analysis system ....Predictive Assessment Tool for Beach Conditions Using Video Imaging and Neural Network Analysis. Beaches are vital part of Australian lifestyle and economic development. Monitoring of variable beach conditions is vital for beach safety and for management of storm erosion. The aim of this project is to develop an assessment tool which will permit a rating system of beach conditions both from an environmental as well as a leisure aspect. This tool will be developed into a software analysis system which will include components of artificial intelligence to enable the system to use feedback loops to create a better prediction of the beach morphology relative to the breaking wave characteristics.Read moreRead less
A New Approach to Studying Whole Bodies and Body Parts Applied to Problems of Forensic Science. To bring to the study of whole humans and human body parts, new methods capable of major advances such as those already provided by DNA technology in the study of human tissues, cells and molecules. This will allow better identification of human groups, geographic populations, gender differences and ageing.
To update facilities in forensic sciences strengthening Australian security systems thus he ....A New Approach to Studying Whole Bodies and Body Parts Applied to Problems of Forensic Science. To bring to the study of whole humans and human body parts, new methods capable of major advances such as those already provided by DNA technology in the study of human tissues, cells and molecules. This will allow better identification of human groups, geographic populations, gender differences and ageing.
To update facilities in forensic sciences strengthening Australian security systems thus helping fight terrorism and crime.
To establish international collaborations for Australia, especially with Asia.
To train young people, through Master's and Doctoral degrees programmes, in handling the new techniques and applying them to problems of forensic science
Read moreRead less
Economic Operability Assessment of Leaching Process at Kwinana Nickel Refinery. Process operability is concerned with systematic analysis and improvement of process performance in the face of variable operating conditions. This project will develop a rigorous methodology for analysis of process operability with respect to short-term and transient disturbances. The proposed technique will be applied to the Kwinana Nickel Refinery Leach section, in order to reduce the plant variability and increas ....Economic Operability Assessment of Leaching Process at Kwinana Nickel Refinery. Process operability is concerned with systematic analysis and improvement of process performance in the face of variable operating conditions. This project will develop a rigorous methodology for analysis of process operability with respect to short-term and transient disturbances. The proposed technique will be applied to the Kwinana Nickel Refinery Leach section, in order to reduce the plant variability and increase nickel throughput and plant availability. This can be considered as significant move by a process industry to embrace advanced theoretical developments and will act as a benchmark to promote future links between Australian industry and academia.Read moreRead less
Towards Distributed Phased Array Radar for High Resolution Weather Monitoring. Several recent reports on climate change by leading international and national bodies forecast that the rate of weather hazards such as storms and wind-shear, and of weather-associated phenomena such as bush fires will increase over the next 40 years. The current technology for monitoring weather events, and effects like wind-shift, which has a serious impact on dangers associated with bush fires, has significant wea ....Towards Distributed Phased Array Radar for High Resolution Weather Monitoring. Several recent reports on climate change by leading international and national bodies forecast that the rate of weather hazards such as storms and wind-shear, and of weather-associated phenomena such as bush fires will increase over the next 40 years. The current technology for monitoring weather events, and effects like wind-shift, which has a serious impact on dangers associated with bush fires, has significant weaknesses. We will deliver considerable improvements in monitoring capability by developing the technology for using a network of small phased array radars. We aim to place monitoring resources where end-user needs are greatest.Read moreRead less
WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production ....WAVELET-BASED MODELLING AND MODEL PREDICTIVE CONTROL OF COMPLEX MULTIDIMENSIONAL CRYSTALLISATION PROCESSES. The results of this project will directly contribute to a better understanding of crystallisation which is an important unit operation to achieve high purity separations. Many Australian industries for example, mineral processing, sugar processing, pharmaceuticals, etc will benefit from the results in order to enhance optimal operation and control to ensure globally competitive production which is on time, minimize wastes and raw materials and inventories. The leading edge results will increase the contributions of these industries to the Australian economy and our global competitiveness necessary to maintain our culture and the beauty of our environment. Read moreRead less