ARC Centre of Excellence - In Plant Energy Biology (CPEB). Plant cell metabolism underlies the synthesis of important products in crops, and subtle changes in metabolism can enhance germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Research in CPEB will focus on control of this metabolism. Its expertise will enhance Australia's participation in major international research efforts directly relevant to sustainable agriculture in a country with fragile/ ....ARC Centre of Excellence - In Plant Energy Biology (CPEB). Plant cell metabolism underlies the synthesis of important products in crops, and subtle changes in metabolism can enhance germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Research in CPEB will focus on control of this metabolism. Its expertise will enhance Australia's participation in major international research efforts directly relevant to sustainable agriculture in a country with fragile/degrading ecosystems. The research will provide new approaches for enhancing quality metabolite traits important for human health. It will further strengthen our international leadership in plant energy science, and will strengthen Australia's research training in systems biology to influence plant function.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989986
Funder
Australian Research Council
Funding Amount
$230,000.00
Summary
Hybrid Fourier Transform Dispersive Raman Micro-Spectrometer. This facility will be used in a wide range of existing and new research projects in government priority areas such as the development of new materials, frontier technologies for building and transforming existing industries, better understanding of diversity and functioning in mycorrhizal and other fungi in forest soils and plant roots and developing new characterisation methods for forensic investigations. The proposed equipment aims ....Hybrid Fourier Transform Dispersive Raman Micro-Spectrometer. This facility will be used in a wide range of existing and new research projects in government priority areas such as the development of new materials, frontier technologies for building and transforming existing industries, better understanding of diversity and functioning in mycorrhizal and other fungi in forest soils and plant roots and developing new characterisation methods for forensic investigations. The proposed equipment aims to provide outstanding opportunities for the training of research students, expanding research in the fields of materials, minerals, geological, environmental and forensic science enabling to maintain Australia's lead and competitiveness in cutting edge research and technology. Read moreRead less
Mechanisms And Therapies In Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$8,360,700.00
Summary
Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting ....Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting new knowledge through integrated research.Read moreRead less
Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all h ....Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all higher organisms, we expect our community will benefit from the increased knowledge base that will help our researchers adopt new strategies in fighting diseases and improving our agricultural industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668155
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Instrumentation for combined seismic and electromagnetic Earth sounding. The set of geophysical recorders will provide the means to enhance understanding of the structure of the Australian continent in 3-D. The interpretation of multiple images of Earth structure will help to link features in the crust and mantle beneath, and provide controls on the evolution and assembly of the present continent, with a major contribution to possible geotransects as recommended in the 2003 National Strategic Pl ....Instrumentation for combined seismic and electromagnetic Earth sounding. The set of geophysical recorders will provide the means to enhance understanding of the structure of the Australian continent in 3-D. The interpretation of multiple images of Earth structure will help to link features in the crust and mantle beneath, and provide controls on the evolution and assembly of the present continent, with a major contribution to possible geotransects as recommended in the 2003 National Strategic Plan for the Geosciences. Combining seismic and electromagnetic methods will provide both geochemeical and geophysical constaints, e.g., on zones of alteration and shear with the potential for deep mineralisation. Read moreRead less
Estimating And Alleviating The Impacts Of Age-Related Sensory Decline
Funder
National Health and Medical Research Council
Funding Amount
$323,767.00
Summary
Sensory loss and dementia disproportionately affect older adults, often co-occur, and are the two leading contributors to disability burden among older Australians. This research will investigate the consequences that hearing and vision loss have for older adult health and wellbeing, informing strategies to reduce the disability burden of age-related sensory loss. These impacts include cognitive decline and dementia, mental health, quality of life, disability and independent living.
Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Multiblock copolymer synthesis for nano-engineered materials. This project aims to develop methodology for environmentally friendly and industrially applicable synthesis of new types of advanced polymeric materials comprising multiblock copolymers. Polymeric materials play an important role in society with applications from bulk plastics to advanced technological applications. This would enable the creation of advanced materials with specific engineering targets and applications ranging from nan ....Multiblock copolymer synthesis for nano-engineered materials. This project aims to develop methodology for environmentally friendly and industrially applicable synthesis of new types of advanced polymeric materials comprising multiblock copolymers. Polymeric materials play an important role in society with applications from bulk plastics to advanced technological applications. This would enable the creation of advanced materials with specific engineering targets and applications ranging from nanomedicine to materials science.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100095
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Frontiers in integrated laser-sampled trace-element and isotopic geoanalysis. Until around 2005 Australia was a leader in the coupling of laser-ablation microprobes (LAM) with inductively-coupled-plasma mass spectrometers (ICPMS) for geochemical research. However, international developments in femtosecond LAM, sector field instruments and novel instrument coupling possibilities have leap-frogged these achievements. The proposed innovative facility will allow us to regain the leading edge in thi ....Frontiers in integrated laser-sampled trace-element and isotopic geoanalysis. Until around 2005 Australia was a leader in the coupling of laser-ablation microprobes (LAM) with inductively-coupled-plasma mass spectrometers (ICPMS) for geochemical research. However, international developments in femtosecond LAM, sector field instruments and novel instrument coupling possibilities have leap-frogged these achievements. The proposed innovative facility will allow us to regain the leading edge in this field, help maintain the high profile of Australian geoscience internationally, and to attract high-quality researchers and industry-related research funding. The research is relevant to the Deep Earth Resources National Priority and will include projects of direct relevance to mineral exploration and process technology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775533
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
A New Generation Noble Gas Mass Spectrometer Facility for Advanced Research in the Earth, Planetary and Environmental Sciences. The current proposal, to establish a new Noble Gas Analytical Consortium for noble gas chronological and geochemical analyses, will generate new knowledge on the evolution of the Earth, with profound implications for past climate change, landscape evolution, formation of ore bodies, and terrestrial geodynamics. Consequently, the facility will conform to the National Res ....A New Generation Noble Gas Mass Spectrometer Facility for Advanced Research in the Earth, Planetary and Environmental Sciences. The current proposal, to establish a new Noble Gas Analytical Consortium for noble gas chronological and geochemical analyses, will generate new knowledge on the evolution of the Earth, with profound implications for past climate change, landscape evolution, formation of ore bodies, and terrestrial geodynamics. Consequently, the facility will conform to the National Research Priority of 'An Environmentally Sustainable Australia'. The new facility will ensure that Australian research remains at the forefront of international science development and will also provide essential training for the next generation of Australian scientists.Read moreRead less