Molecular and genetic analysis of epigenetic components in a model plant. Australia is a major exporter of agricultural food crops thus producers must maintain their competitive advantage in order to compete on the world stage. Food crops unfortunately have large, complex genomes that are not sequenced and a generation time of months that makes research outcomes slow to achieve. This project proposes to utilise a model plant that has a small completely sequenced genome and a short generation tim ....Molecular and genetic analysis of epigenetic components in a model plant. Australia is a major exporter of agricultural food crops thus producers must maintain their competitive advantage in order to compete on the world stage. Food crops unfortunately have large, complex genomes that are not sequenced and a generation time of months that makes research outcomes slow to achieve. This project proposes to utilise a model plant that has a small completely sequenced genome and a short generation time making it ideal to study the fundamental biological process of RNA silencing. Discoveries and outcomes from this project may have the potential to benefit Australian crops, ecosystems and human health.Read moreRead less
Asymmetric Synthesis of Chiral Phosphines, Arsines, and Stibines. There are now chiral phosphine-transition metal catalysts that rival enzymes in their efficiency for the asymmetric synthesis of important chiral drugs, fragrants, cosmetics, nutrients, vitamins, and pesticides. This project is aimed at a generalised asymmetric synthesis of the critical components of these enzyme mimics, notably enantiopure chiral phosphines, but also chiral arsines and stibines, by a highly innovative approach t ....Asymmetric Synthesis of Chiral Phosphines, Arsines, and Stibines. There are now chiral phosphine-transition metal catalysts that rival enzymes in their efficiency for the asymmetric synthesis of important chiral drugs, fragrants, cosmetics, nutrients, vitamins, and pesticides. This project is aimed at a generalised asymmetric synthesis of the critical components of these enzyme mimics, notably enantiopure chiral phosphines, but also chiral arsines and stibines, by a highly innovative approach that involves novel six-electron phosphenium, arsenium, and stibinium cations that are themselves stabilised by chiral phosphines so that chemical breeder reactions are possible. The use of chiral auxiliaries from the natural pool and from biotechnology will also be investigated.Read moreRead less
CRATON EDGES AND SUTURES IN THE AUSTRALIAN MANTLE. A major seismic experiment using recording of distant earthquakes will be used to provide images of 3-D structure in the Earth's crust and mantle along the length of the edge of the Precambrian Australian Shield and across the suture between the South and North Australian cratons within the Shield. Seismic structures derived from different classes of geodynamic models will be compared with seismic results derived from a variety of styles of dat ....CRATON EDGES AND SUTURES IN THE AUSTRALIAN MANTLE. A major seismic experiment using recording of distant earthquakes will be used to provide images of 3-D structure in the Earth's crust and mantle along the length of the edge of the Precambrian Australian Shield and across the suture between the South and North Australian cratons within the Shield. Seismic structures derived from different classes of geodynamic models will be compared with seismic results derived from a variety of styles of data interpretation, including seismic tomography. The experiment will improve understanding of the range of physical processes associated with rifting and building of continents.Read moreRead less
Diamonds - a window into the ancient mantle: the origin of Earth's atmosphere and outgassing of the mantle. The project will provide a better understanding of the mantle source regions of diamonds and, in particular, homogeneity/heterogeneity of the source regions as a function of space and time - potentially of economic significance for diamond exploration. The project will investigate the noble gas compositions of a systematic selection of diamonds of different ages and from different parts of ....Diamonds - a window into the ancient mantle: the origin of Earth's atmosphere and outgassing of the mantle. The project will provide a better understanding of the mantle source regions of diamonds and, in particular, homogeneity/heterogeneity of the source regions as a function of space and time - potentially of economic significance for diamond exploration. The project will investigate the noble gas compositions of a systematic selection of diamonds of different ages and from different parts of the mantle. Together with carbon and nitrogen isotope systematics, this information will be used to better constrain models of Earth outgassing and the evolution of the Earth's atmosphere and mantle.Read moreRead less
Seismic constraints on the assembly of cratons. Improved definition of the 3-D seismological structure and nature of the major lithospheric blocks in Australia and their assembly to form the present-day continent will be sought from seismological data. The inclusion of information on the depth extent and character of the lithosphere will improve geological understanding of the evolution of the continent, with relevance to the interaction of the crust and mantle and the placement of mineral res ....Seismic constraints on the assembly of cratons. Improved definition of the 3-D seismological structure and nature of the major lithospheric blocks in Australia and their assembly to form the present-day continent will be sought from seismological data. The inclusion of information on the depth extent and character of the lithosphere will improve geological understanding of the evolution of the continent, with relevance to the interaction of the crust and mantle and the placement of mineral resources.Read moreRead less
Identifying genes controlling the regulatory and metabolic interactions between the energy organelles of the leaf. Plant energy metabolism underlies the synthesis of many important products in crops, and subtle changes in metabolism can enhance key plant traits, such as germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Furthering our understanding on the complex interplay of genes controlling energy metabolism and its impact on leaf function has potent ....Identifying genes controlling the regulatory and metabolic interactions between the energy organelles of the leaf. Plant energy metabolism underlies the synthesis of many important products in crops, and subtle changes in metabolism can enhance key plant traits, such as germination rates, early seedling vigour, biomass/yield, and tolerance to harsh environments. Furthering our understanding on the complex interplay of genes controlling energy metabolism and its impact on leaf function has potential outcomes for smart genetic manipulation either by classical breeding or genetic transformation. There are more than 10,000 genes of unknown function in plant genomes and this represents a tremendous untapped resource for future Australian R&D outcomes and insights from this research proposal will have application to all plant-based agriculture.Read moreRead less
Time- and Temperature-Dependence of the Fluid Transport Properties, Strength and Mechanical Behaviour of Crustal Faults - An Experimental and Modelling Study. High temperature rock deformation experiments will be performed in conjunction with high resolution, computer-aided x-ray microtomography to determine time-dependent and temperature-dependent effects on fluid transport properties, strength and mechanical behaviour during slip and interseismic healing of simulated fault rocks in hydrotherma ....Time- and Temperature-Dependence of the Fluid Transport Properties, Strength and Mechanical Behaviour of Crustal Faults - An Experimental and Modelling Study. High temperature rock deformation experiments will be performed in conjunction with high resolution, computer-aided x-ray microtomography to determine time-dependent and temperature-dependent effects on fluid transport properties, strength and mechanical behaviour during slip and interseismic healing of simulated fault rocks in hydrothermal environments. The results will be used with cellular automaton modelling approaches to develop a quantitative understanding of how coupling between fluid flow and rock deformation controls earthquake rupture and fluid migration in fault networks in the continental seismogenic regime. This work will provide new understanding of triggers for earthquake nucleation and controls on localisation of ore deposits.Read moreRead less
Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all h ....Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all higher organisms, we expect our community will benefit from the increased knowledge base that will help our researchers adopt new strategies in fighting diseases and improving our agricultural industry.Read moreRead less
Platinum deposit genesis: A new way of thinking. Platinum is becoming increasingly crucial to the high technology sector, and is used particularly in catalytic converters and fuel cells, which serve to minimise or eliminate car exhaust pollution. Greatly expanded resources of this precious metal are needed to help society's transition to a low carbon dioxide (CO2) lifestyle. This project will combine high temperature-pressure experiments with geological field research to greatly improve our unde ....Platinum deposit genesis: A new way of thinking. Platinum is becoming increasingly crucial to the high technology sector, and is used particularly in catalytic converters and fuel cells, which serve to minimise or eliminate car exhaust pollution. Greatly expanded resources of this precious metal are needed to help society's transition to a low carbon dioxide (CO2) lifestyle. This project will combine high temperature-pressure experiments with geological field research to greatly improve our understanding of how platinum ore deposits form and thus where to find them. The outcomes of this project will change mineral exploration strategies in Australia and around the world, and facilitate our progression to a cleaner, greener future.Read moreRead less
Tectonic mode switches and the nature of orogenesis. Tectonic mode switches coincide with short periods of time during which base and precious metals, as well as diamond-bearing kimberlites are emplaced into the continental crust. Our research is aimed at uncovering why this should be so, thereby perhaps solving a riddle that is at the present little more than an oddity in respect to mineral exploration. If we can understand the underlying science we may be able to provide practical benefits t ....Tectonic mode switches and the nature of orogenesis. Tectonic mode switches coincide with short periods of time during which base and precious metals, as well as diamond-bearing kimberlites are emplaced into the continental crust. Our research is aimed at uncovering why this should be so, thereby perhaps solving a riddle that is at the present little more than an oddity in respect to mineral exploration. If we can understand the underlying science we may be able to provide practical benefits to mineral explorers. The project uses modelling and simulation research infrastructure provided by the AuScope NCRIS initiative, and benefits the community by returning data to this organization.Read moreRead less