The Implementation And Evaluation Of Living Evidence In The Management Of Chronic Kidney Disease.
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Chronic kidney disease (CKD) is a growing health problem. Improving outcomes for patients with CKD requires the translation of research into clinical care. However, scientific research that underpins the management of CKD has rapidly increased, and traditional methods to summarise and inform clinical care are out of date. This project will develop, evaluate, and implement a new approach, known as ‘living-evidence’, that translates research evidence in real-time into the management of patients.
Transforming Early Detection Of Cancer In Primary Care
Funder
National Health and Medical Research Council
Funding Amount
$2,360,520.00
Summary
Detecting cancer early is important to improve survival and quality of life. Cancer can be detected through cancer screening or timely diagnosis of patients when they present to their GP with symptoms. This program will transform approaches to detecting cancer earlier in primary care through advances in computer-aided diagnosis and use of new genetic tests to find people at increased risk of cancer.
Improving Influenza Vaccination Rate For The Prevention Of Cardiovascular Events
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Over the next 5 years, I will become an independent researcher and lead a program of work that improves heart care. My research will assess the association between high dose flu vaccine and the prevention of heart disease and test a general practice quality improvement program to enhance vaccination rate in Australia. This will deepen our understanding of the effect of flu vaccination and provide evidence to assist in generating guidelines/policies to help reduce heart disease among Australians.
Patient-centred Volunteer Program For People With Dementia: A Stepped Wedge Cluster Randomised Controlled Trial Of The MyCare Ageing Program
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
The MyCare Ageing program provides hospitalised patients with dementia and/or delirium with tailored emotional and practical support via trained volunteers in hospital and in the transition home. This project will provide critical information on whether MyCare Ageing works to reduce future hospitalisations and prevent poor patient outcomes, the factors that impact on how the program is delivered in hospital and in the community, and whether the program is cost-effective.
How To Address The ‘Shocking Tale Of Neglect’ In Aged Care Through Transparency, Accountability, And The Use Of High-Quality Analytics
Funder
National Health and Medical Research Council
Funding Amount
$1,337,350.00
Summary
The Royal Commission into Aged Care shows that an improved understanding of how the aged care sector is caring for older Australians is a national priority. The Registry of Senior Australians, a large-scale registry database that I developed, will be used to evaluate the health and wellbeing of older Australians. This research will enable me to develop and implement a transparent outcome monitoring system and tools to address the “Shocking Tale of Neglect” older Australians are experiencing.
Delineating The Role Of Fludrocortisone And Hydrocortisone In The Management Of Patients With Septic Shock
Funder
National Health and Medical Research Council
Funding Amount
$553,664.00
Summary
Sepsis and septic shock are leading causes of morbidity and mortality globally. Steroids have been used to treat septic shock for decades. Two new trials, one using hydrocortisone vs. placebo and another using hydrocortisone plus fludrocortisone vs. placebo have produced differing results, with fludrocortisone possibly conferring a mortality benefit. My Program will investigate this evidence gap by providing critical evidence for the design and execution of a future definitive trial.
Improved Early Respiratory Support Of Infants And Children
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Worldwide respiratory disease in children has the highest health care burden on society. Children aged <5 years in particular, are increasing in hospital admissions and to intensive care where the cost is elevated. New ways of oxygen therapy have been studied and shown that we can reduce ICU admission if a therapy known as Nasal High Flow (NHF) therapy is applied earlier in the progression of the disease. Further research is needed in NHF therapy and to improve upon our patient outcomes.
Improving Patient Outcomes Through Better Use Of Blood Products
Funder
National Health and Medical Research Council
Funding Amount
$1,412,250.00
Summary
Blood transfusions, used wisely, save lives. Blood must be used judiciously: it is donated by volunteers, and carries risks and great cost to the community. Although a common intervention, evidence in many areas is inadequate to formulate recommendations on how blood should be used. This research program will address national priorities where evidence is weak by undertaking clinical trials to compare transfusion strategies, evaluate alternatives to transfusion and test novel blood components.
Improving Epidemiological Risk Assessment Of Influenza Epidemics
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Severe flu epidemics have killed young mothers, teenagers, young children and many older people in recent years. Systems for monitoring the flu in Australia and other countries are limited in their ability to provide sound risk assessment during an evolving epidemic. The research I lead will show how unused and under-used data sources can be harnessed to provide a strong influenza risk and healthcare impact assessment capability.
Better Evidence More Rapidly Implemented To Optimise Health For People With Musculoskeletal Conditions
Funder
National Health and Medical Research Council
Funding Amount
$2,914,215.00
Summary
Musculoskeletal conditions place a huge burden on the world’s population. There remain large gaps in the evidence, large delays in getting evidence into practice and policy, and large societal and clinician misconceptions about best care for these conditions. My focus for the next five years will be to improve outcomes for people with musculoskeletal conditions through better evidence, more rapid uptake of evidence into practice, and better strategies to reduce low-value care.