Rolling It Out: Targeted Translation Intervention To Improve Driving Cessation Outcomes For People With Dementia Across Metropolitan And Regional Areas
Funder
National Health and Medical Research Council
Funding Amount
$594,644.00
Summary
This research addresses social, emotional and practical challenges that people with dementia face in dealing with stopping driving. A resource that provides practical and emotional support and education around stopping driving is required in primary care settings to improve quality of life of people with dementia and their carers, and support health professionals who monitor driving issues. This program will translate a research-based resource into GP clinics and community services in Australia.
ImpleMentAll: Towards Evidence-based Tailored Implementation Strategies For EHealth
Funder
National Health and Medical Research Council
Funding Amount
$459,914.00
Summary
Internet-based programs to treat depression and anxiety (“iCBT” programs) are highly effective. However, there are barriers to increased public use of these programs. This project will test ways to improve the implementation of iCBT in clinical services, with a focus on GP practices. Specifically, two Australian-led subprojects will: (i) trial implementation of stepped care, tailoring care to individual needs, and (ii) compare implementation of iCBT in GP practices, pharmacies and online.
Improving Detection And Management Of DEmentia In Older Aboriginal And Torres Strait Islanders Attending Primary Care (IDEA-PC)
Funder
National Health and Medical Research Council
Funding Amount
$2,172,422.00
Summary
This project will co-design, implement and evaluate a nationwide culturally responsive model of care for primary care professionals to optimise the detection and management of dementia and cognitive impairment in older Aboriginal and Torres Strait Islander Australians. Rates of dementia are triple those of other communities and this research aims to optimise the well- being for older people with dementia, their families and communities throughout their journey of care.
The European Commission study - Models of Child Health Appraised (MOCHA) will examine the most effective model of primary health care (medical and non-medical) for children. We will complement this work through specific Australian studies on (1) experiences at the primary/secondary care interface, (2) development and testing of paediatric quality measures and (3) determining if and how primary care addresses inequity; ensuring all the results are translatable outside the European context.
Systematic Medical Appraisal, Referral And Treatment For Common Mental Disorders In India - SMART Mental Health
Funder
National Health and Medical Research Council
Funding Amount
$1,957,608.00
Summary
An estimated 150 million Indians have mental health disorders and the vast majority receive no care whatsoever. We have developed a solution to strengthen India's primary healthcare system comprising village-based anti-stigma campaigns, and a workforce strategy that leverages the skills of doctors and non-physician frontline workers through use of mobile health technologies. It will be tested in North and South India in a large-scale trial involving 44,000 people and 20 primary health centres.
Breast Cancer Risk After Diagnostic Gene Sequencing (BRIDGES)
Funder
National Health and Medical Research Council
Funding Amount
$471,281.00
Summary
In BRIDGES, we aim to build a knowledge base to better define individual breast cancer risk. We bring together, in a multidisciplinary team, data and expertise from clinical genetics, epidemiology, bioinformatics, statistics, and gene biology. Specifically, we will use state-of-the art DNA screening to evaluate all suspected breast cancer genes in a large sample of breast cancer cases and controls. We will then use in silico and in vitro functional analyses to evaluate the likely pathogenicity o
Breast CAncer STratification: Understanding The Determinants Of Risk And Prognosis Of Molecular Subtypes
Funder
National Health and Medical Research Council
Funding Amount
$472,984.00
Summary
Breast cancer is not one disease, but many different types with different causes, treatments and outcomes. The aim of this project is to use genetic, lifestyle/environmental, mammographic breast density, pathologic and clinical data froma very large number of studies from all over the world to develop ways of predicting which women are at risk of particuar types of breast cancer, and if breast cancer develops what the likely outcome will be.
Early Detection Of Lung Cancer And Mesothelioma In Asbestos Workers At Highest Risk
Funder
National Health and Medical Research Council
Funding Amount
$623,268.00
Summary
Through no fault of their own, many Australian workers have been inadvertently exposed to asbestos and are at high risk of developing lung cancer and mesothelioma. With the peak incidence bearing upon us, there is an urgent need for early detection by CT.
Application Of Omics-based Strategies For Improved Diagnosis And Treatment Of Endocrine Hypertension
Funder
National Health and Medical Research Council
Funding Amount
$461,322.00
Summary
Arterial hypertension affects up to 45% of the general population and is responsible for 7.1 million deaths per year worldwide. We will define specific omics profiles for patients with a range of hypertension-related disorders by integrating high throughput genetics, genomics and metabolomics data. This should allow identification of patients with preclinical phenotypes along with those hypertensives that cluster into specific endocrine groups who may benefit from personalised treatment.
Nutrition And Rehabilitation In Advanced Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$225,991.00
Summary
This preliminary project aims to evaluate associations between cancer cachexia, psychosocial factors and cytokine levels in blood. The final decline of most patients with advanced cancer is associated with the cancer cachexia syndrome, triggered in part by cytokine release. Measuring cytokines may enable identification of patients about to enter this final stage. Further, factors like mood and social support appear to alter cytokine levels. The associations established by this study may point to ....This preliminary project aims to evaluate associations between cancer cachexia, psychosocial factors and cytokine levels in blood. The final decline of most patients with advanced cancer is associated with the cancer cachexia syndrome, triggered in part by cytokine release. Measuring cytokines may enable identification of patients about to enter this final stage. Further, factors like mood and social support appear to alter cytokine levels. The associations established by this study may point to treatment options that can delay the terminal phase while improving quality of life.Read moreRead less