Disposable microfluidic diagnostics for new generation foods, beverages and oral care products. The outcomes of this project will lead to the establishment of a new paradigm in designing foods, beverages and oral care products that have tailored health and vitality benefits (e.g. reduced levels of fat, sugar and salt). In addition, these foods will contain beneficial additives (e.g. anti-oxidants, vitamins, minerals, phytonutrients) targeted to specific consumer groups according to their lifesty ....Disposable microfluidic diagnostics for new generation foods, beverages and oral care products. The outcomes of this project will lead to the establishment of a new paradigm in designing foods, beverages and oral care products that have tailored health and vitality benefits (e.g. reduced levels of fat, sugar and salt). In addition, these foods will contain beneficial additives (e.g. anti-oxidants, vitamins, minerals, phytonutrients) targeted to specific consumer groups according to their lifestyle, age, medical condition or requirement for nutritional/nourishment efficacy, thereby contributing to healthy ageing. It is foreseen that this novel approach to designing foods will be extended to products intended for consumers whose sensory perception is compromised by existing medical therapeutic practices (such as radiation therapy).Read moreRead less
Over the next five years, I will further expand and continue to translate my basic and clinical research programs in women’s health to deliver outcomes to the Australian and international health care systems. In particular, I will target the concept of pregnancy as a determinant of future community health and wellbeing. There is now substantial consensus that environmental influences (including, but not limited to, maternal nutrition) during early life can have a fundamental impact on human deve ....Over the next five years, I will further expand and continue to translate my basic and clinical research programs in women’s health to deliver outcomes to the Australian and international health care systems. In particular, I will target the concept of pregnancy as a determinant of future community health and wellbeing. There is now substantial consensus that environmental influences (including, but not limited to, maternal nutrition) during early life can have a fundamental impact on human development, with consequences for biological and social function and behaviour throughout the lifecourseRead moreRead less
Dietary sugarcane-derived polyphenols reduce obesity. The Australian Sugar Industry is a billion dollar industry with refined sugar being calorie-rich but nutrition poor. Consumption of refined sugar is a main contributor to the increasing problem of obesity and metabolic syndrome, costing the Australian health system billions of dollars annually. The principal outcomes of this project will be to show that the polyphenols contained in the waste products from sugar refining can be used to reduce ....Dietary sugarcane-derived polyphenols reduce obesity. The Australian Sugar Industry is a billion dollar industry with refined sugar being calorie-rich but nutrition poor. Consumption of refined sugar is a main contributor to the increasing problem of obesity and metabolic syndrome, costing the Australian health system billions of dollars annually. The principal outcomes of this project will be to show that the polyphenols contained in the waste products from sugar refining can be used to reduce body fat and insulin resistance. These outcomes have enormous implications for human health and disease, and for the sugar industry, thus providing a competitive edge in the world sugar market.Read moreRead less
Establishing evidence for the functional properties of a whole grain in weight management. The successful development of functional foods relies on communicating proven effects. This project aims to prove that the food containing the satiety properties of a whole grain (OG) may help in weight management. We will conduct basic research investigating the link between consumption of OG-containing foods and the regulatory mechanisms of satiety, and test whether the satiety properties can be used to ....Establishing evidence for the functional properties of a whole grain in weight management. The successful development of functional foods relies on communicating proven effects. This project aims to prove that the food containing the satiety properties of a whole grain (OG) may help in weight management. We will conduct basic research investigating the link between consumption of OG-containing foods and the regulatory mechanisms of satiety, and test whether the satiety properties can be used to prevent, reduce and correct body weight gain in the early, middle and late stages of obesity. We will then apply this understanding in a human trial of mildly and long term overweight subjects, to aid the formulation of statements on the potential health benefits from consuming OG.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453623
Funder
Australian Research Council
Funding Amount
$164,640.00
Summary
Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in re ....Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in regulating bone and mineral metabolism and altering bone properties. This has implications for maximising bone strength and promoting optimal health throughout life. The facility will be used for a diverse range of multidisciplinary basic bone research and is vital in order to maintain international competitiveness in the field.Read moreRead less
Impact of shear stress on vascular adaptations in humans. Large arteries are important for the delivery of blood and oxygen to organs such as the heart and brain. A primary physiological stimulus which controls the size and function of these crucial arteries is the magnitude of flow or, more accurately, shear force that the inner wall of the artery is exposed to. We have developed novel software which enables non-invasive assessment of arterial wall velocity, diameter and blood flow. We will ass ....Impact of shear stress on vascular adaptations in humans. Large arteries are important for the delivery of blood and oxygen to organs such as the heart and brain. A primary physiological stimulus which controls the size and function of these crucial arteries is the magnitude of flow or, more accurately, shear force that the inner wall of the artery is exposed to. We have developed novel software which enables non-invasive assessment of arterial wall velocity, diameter and blood flow. We will assess the impact of acute and chronic changes in wall flow and shear on arterial size and function. We will also develop new software which measures other aspects of artery wall behaviour. These basic human physiology studies have direct implications for assessment of artery health in humans.Read moreRead less