Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the fin ....Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the findings will foster more effective and efficient responses. Additionally, the findings will inform victims of partner violence of risks related to escalation toward fatal outcomes and should facilitate help seeking behaviour. Collectively, project findings should expand understanding, improve service delivery and save lives.
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Pre-clinical evaluation of snake venom proteins with therapeutic potential. Australia harbors some of the most toxic snakes in the world. Their venoms contain a range of substances that are designed to rapidly immobilize and kill their prey. These include agents that lead to enhanced blood clotting; excess bleeding. We have isolated and characterized a large number of the components involved over the last several years. The aim here is to carry out pre-clinical trials in animal models to test th ....Pre-clinical evaluation of snake venom proteins with therapeutic potential. Australia harbors some of the most toxic snakes in the world. Their venoms contain a range of substances that are designed to rapidly immobilize and kill their prey. These include agents that lead to enhanced blood clotting; excess bleeding. We have isolated and characterized a large number of the components involved over the last several years. The aim here is to carry out pre-clinical trials in animal models to test the efficacy of three proteins as anti-bleeding agents and investigate several other novel components. The ultimate outcome will be the development of novel drugs that will have application in the treatment of human disorders. Read moreRead less
The influence of resistance training upon movement control in the elderly. The primary aim of this applied research project is to investigate the impact of resistance training in the elderly. We will assess the responses to training that occur in the elderly, and determine the time course and persistence of adaptation. It is anticipated that the knowledge derived will be applied by clinicians and health practitioners in the design of resistance training programmes for the elderly, and thereby en ....The influence of resistance training upon movement control in the elderly. The primary aim of this applied research project is to investigate the impact of resistance training in the elderly. We will assess the responses to training that occur in the elderly, and determine the time course and persistence of adaptation. It is anticipated that the knowledge derived will be applied by clinicians and health practitioners in the design of resistance training programmes for the elderly, and thereby enhance the performance of tasks encountered in daily living.Read moreRead less
Preparatory processes in rapid interceptive action. This project investigates the nature of the processes involved in preparing to act in response to a moving object: actions that elite sportspeople perform with amazing precision: timing to within a few thousandths of a second is routine when hitting a ball in tennis and cricket. The average person can be capable of something similar and it means being ready to make the right movement at the right time. Understanding the preparatory processes in ....Preparatory processes in rapid interceptive action. This project investigates the nature of the processes involved in preparing to act in response to a moving object: actions that elite sportspeople perform with amazing precision: timing to within a few thousandths of a second is routine when hitting a ball in tennis and cricket. The average person can be capable of something similar and it means being ready to make the right movement at the right time. Understanding the preparatory processes involved will be a significant scientific advance and knowledge of their workings and limits can contribute to the development of strategies for improving safety in dynamic environments such as city roads. This project will put an Australian laboratory at the cutting edge in this area of research.Read moreRead less
Experimental and computational assessment of the mechanical, musculo-skeletal and neuromuscular contributions to rhythmic multi-joint arm movements. The human body is a complex mechanical system that is controlled by a vast neural network comprising many millions of connections. To date, realistic descriptions of the interactions between these neuro-mechanical features have proved elusive. This project seeks to develop a mathematical model that accurately describes the essential features of the ....Experimental and computational assessment of the mechanical, musculo-skeletal and neuromuscular contributions to rhythmic multi-joint arm movements. The human body is a complex mechanical system that is controlled by a vast neural network comprising many millions of connections. To date, realistic descriptions of the interactions between these neuro-mechanical features have proved elusive. This project seeks to develop a mathematical model that accurately describes the essential features of the control system for human movement, and yet is simple enough to inform the design of artificial devices to generate or assist movement. The knowledge derived should improve mechanical and neural prosthetic systems, and guide rehabilitation protocols. The work will ultimately provide a considerable benefit to the community by reducing the social cost of a range of movement disorders.Read moreRead less
An inverse control approach to resolving the neural basis of spatial and muscular dependencies in coordinated multi-limb movements. Each year 48,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will ....An inverse control approach to resolving the neural basis of spatial and muscular dependencies in coordinated multi-limb movements. Each year 48,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of life and functional life-span, as well as significantly reduced costs of health care. In understanding the fundamental principles underlying the stability and adaptability of movement coordination, this research is likely to make a significant contribution to the design of programs for movement rehabilitation.Read moreRead less
Cortical Mechanisms Mediating Bilateral Interactions Between the Upper Limbs. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced qual ....Cortical Mechanisms Mediating Bilateral Interactions Between the Upper Limbs. Each year 40,000 Australians suffer from stroke with many survivors left with problems that limit limb function. With reduced duration of hospital care, the opportunities for retraining in the period immediate following stroke are rapidly diminishing. Effective and efficient strategies of rehabilitation that will maximise the level of recovery following stroke will result in benefits expressed in terms of enhanced quality of life and functional life-span, as well as significantly reduced costs of health care. In understanding the fundamental principles underlying the stability and adaptability of movement coordination, this research is likely to make a significant contribution to the design of programs for rehabilitation of the upper limb.Read moreRead less
The neural basis of interlimb coordination. The aims of the proposed research program are to increase our understanding the control of voluntary movement. It is expected that the outcomes of this research program will have eventual application to a number of acquired movement deficits, in particular those arising from spinal cord and brain injury. This research will also be of diagnostic value in determining the integrity of the motor pathways, in both acquired and developmental movement disorde ....The neural basis of interlimb coordination. The aims of the proposed research program are to increase our understanding the control of voluntary movement. It is expected that the outcomes of this research program will have eventual application to a number of acquired movement deficits, in particular those arising from spinal cord and brain injury. This research will also be of diagnostic value in determining the integrity of the motor pathways, in both acquired and developmental movement disorders.Read moreRead less
Spatio-Temporal Precision of Interceptive Action. Interceptive actions like hitting a moving target require precise, accurate positioning and timing. This project aims to empirically document how spatial and temporal constraints affect performance of interceptions and to quantify the speed-accuracy trade-off for interceptions. The speed-accuracy trade-off for movements aimed at stationary targets has been extensively documented - slower movements are more accurate. There has been no correspondin ....Spatio-Temporal Precision of Interceptive Action. Interceptive actions like hitting a moving target require precise, accurate positioning and timing. This project aims to empirically document how spatial and temporal constraints affect performance of interceptions and to quantify the speed-accuracy trade-off for interceptions. The speed-accuracy trade-off for movements aimed at stationary targets has been extensively documented - slower movements are more accurate. There has been no corresponding documentation for interception. This project will fill the gap and provide a rich data set for developing an understanding of interception through modeling work. An understanding of the factors governing interception has potential applications in road safety, sports and neurological rehabilitation.Read moreRead less
Interceptive Action: Performance, Neuromotor Control and Learning. Natural, everyday environments are dynamic. People, animals and other objects move around and human behaviour must be geared to these motions: people must anticipate where things are going and when they will get there so that undesirable collisions and contacts can be avoided and desirable ones achieved. This project investigates basic modes of interacting with dynamic environments - intercepting and evading objects in motion. T ....Interceptive Action: Performance, Neuromotor Control and Learning. Natural, everyday environments are dynamic. People, animals and other objects move around and human behaviour must be geared to these motions: people must anticipate where things are going and when they will get there so that undesirable collisions and contacts can be avoided and desirable ones achieved. This project investigates basic modes of interacting with dynamic environments - intercepting and evading objects in motion. The aim is to extend our understanding of the principles, control mechanisms and brain structures involved. Such understanding has the potential to contribute to areas such as road safety, autonomous robotics, sports training and neurological rehabilitation.Read moreRead less