Links2HealthierBubs: Influenza And Pertussis Vaccine Effectiveness And Safety In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$676,333.00
Summary
Vaccination during pregnancy can offer protection against severe respiratory disease for infants in the first six months of life. For this reason, influenza and pertussis vaccines are routinely recommended during each pregnancy. Unfortunately, little is known about the ‘real world’ effect of both vaccines. We plan to conduct the largest and most comprehensive study to date to evaluate all vaccines routinely recommended in pregnancy in Australia.
Assessing Vaccine Effectiveness Of Publicly Funded Vaccination Programs In Queensland
Funder
National Health and Medical Research Council
Funding Amount
$99,883.00
Summary
I will measure how well three vaccines on the national immunisation schedule prevent disease in Queensland. Pertussis (whooping cough), rotavirus, and varicella (chicken-pox) vaccines will be assessed using routinely collected health data, such as disease notifications and hospitalisations, and vaccination data. The findings of this research will contribute to evaluating the effectiveness of these publicly funded vaccination programs and will provide an evidence base for future decision-making.
Evaluation And Optimisation Of Paediatric Vaccination Programs In Australia And The Region
Funder
National Health and Medical Research Council
Funding Amount
$293,426.00
Summary
Vaccines are highly effective in preventing infection. Increasing numbers of vaccines are available to children and to national immunisation programs. Research is required to ensure that vaccines included in national programs are effective and safe. We must also understand why some children are not vaccinated and to assess ways to improve uptake. Focusing on two common disease, influenza and pneumococcal disease, this fellowship will address these unanswered questions.
Providing The Evidence To Guide Adult Immunisation Strategies
Funder
National Health and Medical Research Council
Funding Amount
$492,414.00
Summary
Australia's population is ageing and strategies to improve health in older adults are necessary to prevent an increasing burden on our health system. Adult vaccination is a relatively under-researched area with great potential to prevent disease in the population. This project focuses on four common vaccine preventable disease in adults, herpes zoster (shingles), influenza, invasive pneumococcal disease and pertussis. It will identify what their impact is on the health system and what groups of ....Australia's population is ageing and strategies to improve health in older adults are necessary to prevent an increasing burden on our health system. Adult vaccination is a relatively under-researched area with great potential to prevent disease in the population. This project focuses on four common vaccine preventable disease in adults, herpes zoster (shingles), influenza, invasive pneumococcal disease and pertussis. It will identify what their impact is on the health system and what groups of adults would benefit most from vaccination.Read moreRead less
Prevention Of Pertussis From Birth Through Maternal Immunisation
Funder
National Health and Medical Research Council
Funding Amount
$197,657.00
Summary
Whooping cough or pertussis is a significant cause of death in infants worldwide. Newborns remain at risk until they have received 1 to 2 doses of pertussis vaccine (around 4 months of age). My project involves investigating whether giving pertussis vaccine in the third trimester of pregnancy provides passive protection (via transplacental transfer of antibody) to the infant in sufficient levels for protection against whooping cough in early infancy.
RV3 Rotavirus Vaccine: Phase I And II Clinical Trials Of A Human Neonatal Rotavirus Vaccine For The Global Community
Funder
National Health and Medical Research Council
Funding Amount
$1,099,123.00
Summary
Rotavirus infection is the leading cause of gastroenteritis responsible for over 600,000 deaths each year in children less than 5 years. Although 2 commercial vaccines are now available in Australia, the high cost and concern about the risk of side effects are barriers to widespread vaccine introduction. The goal of this study is to develop an effective rotavirus vaccine, administered to newborns that is affordable for the global community, able to be introduced cheaply in developing countries w ....Rotavirus infection is the leading cause of gastroenteritis responsible for over 600,000 deaths each year in children less than 5 years. Although 2 commercial vaccines are now available in Australia, the high cost and concern about the risk of side effects are barriers to widespread vaccine introduction. The goal of this study is to develop an effective rotavirus vaccine, administered to newborns that is affordable for the global community, able to be introduced cheaply in developing countries where the burden of morbidity and mortality is greatest.Read moreRead less
Immunisation In Under Studied And Special Risk Populations: Closing The Gap In Knowledge Through A Multidisciplinary Approach
Funder
National Health and Medical Research Council
Funding Amount
$2,499,969.00
Summary
Much of the vaccine research which informs national policy is conducted by the pharmaceutical industry or by government. However, there are critical research gaps in special-risk and under-served populations where targeted research is not commercially viable. These include research in the extremes of age, Indigenous Australians, migrants, refugees, immunosuppressed and traveller populations. This CRE will address research gaps in such populations, which have not been addressed elsewhere, using n ....Much of the vaccine research which informs national policy is conducted by the pharmaceutical industry or by government. However, there are critical research gaps in special-risk and under-served populations where targeted research is not commercially viable. These include research in the extremes of age, Indigenous Australians, migrants, refugees, immunosuppressed and traveller populations. This CRE will address research gaps in such populations, which have not been addressed elsewhere, using novel, multidisciplinary methods.Read moreRead less