The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your
interaction with the ARDC and use of our national research infrastructure and services. The survey will take
approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure
services including Reasearch Link Australia.
We will use the information you provide to improve the national research infrastructure and services we
deliver and to report on user satisfaction to the Australian Government’s National Collaborative Research
Infrastructure Strategy (NCRIS) program.
Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
Investigating The Relationship Between Depression, Anxiety And Nausea And Vomiting During Pregnancy: Causation Or Shared Liability?
Funder
National Health and Medical Research Council
Funding Amount
$600,874.00
Summary
Recent studies showing women who experience severe Nausea and vomiting during pregnancy (NVP) have higher rates of Anxiety and Depression prior to pregnancy have revived earlier hypotheses that NVP may have a psychogenic component. We hypothesize that Anxiety and Depression do not play a causal role in NVP but rather, the relationship is due to shared risk from genetic effects that influence both traits. We will test this hypothesis using genetic and epidemiological approaches.
Functional Contribution Of Fetal Microchimeric Cells In Transgenic Models Of Maternal Tissue Repair In And After Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$542,462.00
Summary
Fetal stem cells cross into the mother during pregnancy and persist lifelong in her tissues. To determine whether helpful or harmful, we will study how these cells contribute to healing both after acute injury and in chronic genetic models like brittle-bone disease and muscular dystrophy. This research will inform long-term consequences of pregnancy, important for women's health and longevity, and help develop a promising form of stem cell therapy.
Individualising Care For Patients With Chronic Hepatitis C: Predicting Side Effects And Treatment Response Using Genomic And Proteomic Approaches.
Funder
National Health and Medical Research Council
Funding Amount
$55,575.00
Summary
Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially impro ....Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially improving the safety and efficacy of therapy.Read moreRead less
STudy Of Risk Assessment To Reduce Complications In Patients Following Noncardiac SurgerY (STRATIFY)
Funder
National Health and Medical Research Council
Funding Amount
$436,000.00
Summary
Cardiac problems account for many complications in patients undergoing major non-cardiac surgery, and even apparently minor cardiac damage is a marker of high risk for subsequent adverse events. Unfortunately, while money and effort is expended on identifying patients at risk, the appropriate response to this risk is quite unclear. The performance of bypass surgery or balloon angioplasty in order to treat the underlying coronary disease of at-risk patients is used in other situations, and reduce ....Cardiac problems account for many complications in patients undergoing major non-cardiac surgery, and even apparently minor cardiac damage is a marker of high risk for subsequent adverse events. Unfortunately, while money and effort is expended on identifying patients at risk, the appropriate response to this risk is quite unclear. The performance of bypass surgery or balloon angioplasty in order to treat the underlying coronary disease of at-risk patients is used in other situations, and reduces longterm risk. However, in many patients undergoing major noncardiac surgery, this approach may be inappropriately aggressive, as these patients are often elderly, have other diseases that make heart operations more difficult and risky than usual, and in any case may have a reduced life expectancy from the disease necessitating the operation. As the most critical issue is to ensure that patients undergo their surgery uneventfully, an alternative is the use of intensive medical therapy to protect the heart. This multicentre study, based at Brisbane hospitals that perform large numbers of major operations, will follow up patients for complications, and outcome (including quality of life) will be assessed six months after the operation. We will address two important questions about the efficacy and cost of risk reduction strategies. First, in patients at higher levels of risk and with a positive stress test, could a combination of medical therapy designed to protect the heart be as effective as current approaches, which include the performance of bypass surgery or coronary balloon angioplasty? Second, in patients identified as being at some risk - but low risk - are drugs sufficiently effective to avoid the need for further testing to quantify risk? As the population continues to age, the numbers of at risk patients undergoing major surgery will increase, and answers to these questions will provide important information to guide their management.Read moreRead less
The Functional Roles Of ADAMs In The Regulation Of Embryo Implantation.
Funder
National Health and Medical Research Council
Funding Amount
$211,527.00
Summary
The initiation of pregnancy in humans and rodents hinges upon the ability of the embryo to attach to the wall of the uterus and invade into the uterine tissue. This process of embryo implantation is tightly regulated and depends on the secretion of enzymes and regulators of these enzymes. A newly identified family of enzymes which might be important in this process is the ADAMs family. These enzymes have the potential to facilitate both cell attachment and cell invasion and also to activate othe ....The initiation of pregnancy in humans and rodents hinges upon the ability of the embryo to attach to the wall of the uterus and invade into the uterine tissue. This process of embryo implantation is tightly regulated and depends on the secretion of enzymes and regulators of these enzymes. A newly identified family of enzymes which might be important in this process is the ADAMs family. These enzymes have the potential to facilitate both cell attachment and cell invasion and also to activate other enzymes and growth factors. Recent studies in our laboratory have shown the ADAMs to be expressed both at the most invasive time of implantation and when invasion is being down-regulated. This project will examine the role of the ADAMs in embryo implantation facilitating attachment and invasion into the uterus by acting enzymatically on the uterine tissue and by activating other enzymes. It will also determine the role of ADAMs in down-regulating invasion potentially by activating a growth factor, TNF-alpha. Knowledge of this process and particularly its regulation is important for the treatment of pregnancy associated diseases that arise from improper implantation. These include infertility, placenta accreta, choriocarcinoma, miscarriage and pre-eclampsia. Furthermore, an understanding of the regulation of implantation will contribute to the treatment of other conditions associated with cell invasion such as cancer metastasis.Read moreRead less
Selling The Punt: An interdisciplinary analysis of the extent and impact of sports wagering marketing strategies in Australia. Sports wagering is the fastest growing segment of the gambling market in Australia. Despite widespread concern about the impact of marketing strategies on the risky consumption of wagering products by young men and adolescents, research and policy has failed to keep up with this rapidly growing industry. This study will provide: detailed information about the range of ma ....Selling The Punt: An interdisciplinary analysis of the extent and impact of sports wagering marketing strategies in Australia. Sports wagering is the fastest growing segment of the gambling market in Australia. Despite widespread concern about the impact of marketing strategies on the risky consumption of wagering products by young men and adolescents, research and policy has failed to keep up with this rapidly growing industry. This study will provide: detailed information about the range of marketing strategies used to sell sports wagering in Australia; important qualitative insights into the impact of these marketing strategies on gambling behaviours; and, recommendations for a comprehensive public health approach to help counter the potential long and short term risks associated with sports wagering marketing.Read moreRead less
Personal alarms - use, expectations and outcomes. Personal alarms are designed to enable older people who are living alone to gain assistance in an emergency. Australia's population is ageing and the number of older people living alone is increasing. Although personal alarms have been available for many years there has been surprisingly little research and there are still many gaps in our knowledge. These limit our ability to maximise the potential of this technology in enabling older Australian ....Personal alarms - use, expectations and outcomes. Personal alarms are designed to enable older people who are living alone to gain assistance in an emergency. Australia's population is ageing and the number of older people living alone is increasing. Although personal alarms have been available for many years there has been surprisingly little research and there are still many gaps in our knowledge. These limit our ability to maximise the potential of this technology in enabling older Australians to age well and productively at home. This project seeks to enhance our understanding of the adoption and appropriate use of this technology by older Australians and inform the development of strategies to achieve maximum benefit for both older individuals and the community at large.Read moreRead less
Both Smart and Healthy: Learning Communities as a Settings-based Approaches to Health Promotion. This project will use a collaborative learning model to build health promotion capacity. The project brings together two innovative approaches to develop new knowledge about how setting-based approaches to health can be implemented in future. This approach could potentially address chronic disease at a national and international level by promoting healthy communities that can effectively manage chr ....Both Smart and Healthy: Learning Communities as a Settings-based Approaches to Health Promotion. This project will use a collaborative learning model to build health promotion capacity. The project brings together two innovative approaches to develop new knowledge about how setting-based approaches to health can be implemented in future. This approach could potentially address chronic disease at a national and international level by promoting healthy communities that can effectively manage chronic disease through collaborative learning and knowledge-building. The project represents an important collaboration between a university and its community with a view to improving health capacity.Read moreRead less
'Just right' job design: A new model using the Goldilocks paradigm. This proposal will generate new knowledge about designing jobs with the right amount of human movement. Prolonged sitting is now a serious work hazard that contributes to cardiovascular risk and obesity. The high incidence of these conditions in many work systems, such as rail, also presents a critical safety hazard due to threat of sudden incapacity while driving. Expected project outcomes are a ‘Just Right’ Job Design model sh ....'Just right' job design: A new model using the Goldilocks paradigm. This proposal will generate new knowledge about designing jobs with the right amount of human movement. Prolonged sitting is now a serious work hazard that contributes to cardiovascular risk and obesity. The high incidence of these conditions in many work systems, such as rail, also presents a critical safety hazard due to threat of sudden incapacity while driving. Expected project outcomes are a ‘Just Right’ Job Design model showing how tasks can be designed to enhance safety and health while maintaining productivity, and in the unlikeliest of workplaces. This will provide significant benefits for the many working Australians whose safety and health are compromised by exposure to prolonged sitting in seemingly intractable environments.Read moreRead less
Identifying Models of Personal and Community Resilience that enhance Psychological Wellness: A Stanthorpe Study. There are significant mental health problems in rural and remote Australia. Researchers in Australia are only just beginning to investigate mental health, and prevention is identified as a primary focus. A new innovative approach to mental health prevention is identifying and using characteristics that will enhance individual and community psychological wellness. Resilience has been i ....Identifying Models of Personal and Community Resilience that enhance Psychological Wellness: A Stanthorpe Study. There are significant mental health problems in rural and remote Australia. Researchers in Australia are only just beginning to investigate mental health, and prevention is identified as a primary focus. A new innovative approach to mental health prevention is identifying and using characteristics that will enhance individual and community psychological wellness. Resilience has been identified as one of those characteristics. The aim of this project is to work collaboratively with key stakeholders from a rural community (Stanthorpe in South East Queensland) to develop, implement, and evaluate a model that enhances psychological wellness in rural people and communities.Read moreRead less