Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668450
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Upgrade of comparative phenotypical and functional cell analysis at James Cook University. North Queensland is a fast growing region with significant need for the development of a world-class research facility. James Cook University has recently established the Comparative Genomics Centre at the School of Pharmacy and Molecular Sciences, which will contribute to education and basic research in the region. The research outcomes from the projects of the Comparative Genomics Centre and affiliated l ....Upgrade of comparative phenotypical and functional cell analysis at James Cook University. North Queensland is a fast growing region with significant need for the development of a world-class research facility. James Cook University has recently established the Comparative Genomics Centre at the School of Pharmacy and Molecular Sciences, which will contribute to education and basic research in the region. The research outcomes from the projects of the Comparative Genomics Centre and affiliated laboratories facilitated by the analytical flow cytometer will support the definition and identification of the interactions between genetic and environmental factors in disease and will help to attract researchers. Results from this work will aid the search for therapies for specific health problems.Read moreRead less
The biology of arbovirus virulence and fitness in arthropod and vertebrate hosts in vivo. In Australia, Ross River virus (RRV) represents significant concern to human health. Between 1992-2005 more than 50,000 notifications of RRV infection have been reported. While not fatal, the disease is responsible for morbidity in the community/individual that can have both social and economic costs. The project has several national benefits. It will help elucidate whether there is any association between ....The biology of arbovirus virulence and fitness in arthropod and vertebrate hosts in vivo. In Australia, Ross River virus (RRV) represents significant concern to human health. Between 1992-2005 more than 50,000 notifications of RRV infection have been reported. While not fatal, the disease is responsible for morbidity in the community/individual that can have both social and economic costs. The project has several national benefits. It will help elucidate whether there is any association between RRV strain and increased risk of RRV transmission and/or occurrence of more severe cases of human disease. It will help develop technologies that can lead towards the identification of viral markers, which could provide new avenues in the design of novel antiviral strategies.
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Disulfide Bonds and Protein Folding. This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology ....Disulfide Bonds and Protein Folding. This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology. This work could yield economic benefits in the long-term through patentable outcomes and will benefit the community by producing high impact research papers, providing training to Australians and forging links with renowned international scientists.Read moreRead less