Effects Of Fast Versus Slow Weight Loss On Fat, Muscle And Bone In Postmenopausal Women
Funder
National Health and Medical Research Council
Funding Amount
$316,450.00
Summary
Very low energy diets (VLED) are increasingly used to treat obesity. Of concern is the fact that VLED induce adaptive responses that can inhibit loss of, and promote regain of, abdominal fat while decreasing lean body mass, muscle strength and bone density. This project will therefore determine whether VLEDs could have negative effects on body composition that increase the risk of metabolic disease, sarcopenia or osteoporosis, and if so, what mechanisms are involved.
Discovery Early Career Researcher Award - Grant ID: DE240100627
Funder
Australian Research Council
Funding Amount
$436,250.00
Summary
Topological phonons in solids. This project aims to create a complete list of possible topological phonons in time-reversal-invariant systems via symmetry analysis, to determine ideal topological phononic materials, and to study topological phonon-related properties and possible applications. The significant outcomes of this project will be the generation of new knowledge that will help conclude the search for novel topological phonons and the prediction of novel topological phononic materials b ....Topological phonons in solids. This project aims to create a complete list of possible topological phonons in time-reversal-invariant systems via symmetry analysis, to determine ideal topological phononic materials, and to study topological phonon-related properties and possible applications. The significant outcomes of this project will be the generation of new knowledge that will help conclude the search for novel topological phonons and the prediction of novel topological phononic materials based on the complete classification list of topological phonons. The outcomes of this project should unlock the physics of the exotic topological phonons and lay a solid foundation for applying topological phononic materials based on their unprecedented properties.Read moreRead less
Hot Topic: Quantum Design of Phononic Heat Filters. Heat management is critical to many technologies for sustainable energy, electronics, protective equipment and energy-efficient buildings. The phonon is the quantum particle representing a travelling vibration and is responsible for the transmission of heat in solids. This project will study the new mechanisms for phonon transport in solids modified with embedded nanoparticles, which operate as phononic filters. Neutron spectroscopy provides a ....Hot Topic: Quantum Design of Phononic Heat Filters. Heat management is critical to many technologies for sustainable energy, electronics, protective equipment and energy-efficient buildings. The phonon is the quantum particle representing a travelling vibration and is responsible for the transmission of heat in solids. This project will study the new mechanisms for phonon transport in solids modified with embedded nanoparticles, which operate as phononic filters. Neutron spectroscopy provides a tool to measure the phonon density of states which is critical for developing a mathematical model of thermal boundary resistance. This is expected to identify mechanisms for ultra-low thermal conductivity leading to potential applications in thermoelectric generators and heat-resistant materials.Read moreRead less
An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
Discovery Early Career Researcher Award - Grant ID: DE150101499
Funder
Australian Research Council
Funding Amount
$355,801.00
Summary
First-principles design and characterisation of topological materials. It has long been predicted that materials may contain special topological order. The recent discovery of topological insulators reveals the tip of the iceberg, but many theoretical hypotheses, such as the existence of the fractional Chern insulator and quantum spin liquid, remain elusive. This project aims to bridge the gap between conceptual models and real materials by using first-principles calculations. The plan is to ide ....First-principles design and characterisation of topological materials. It has long been predicted that materials may contain special topological order. The recent discovery of topological insulators reveals the tip of the iceberg, but many theoretical hypotheses, such as the existence of the fractional Chern insulator and quantum spin liquid, remain elusive. This project aims to bridge the gap between conceptual models and real materials by using first-principles calculations. The plan is to identify and engineer topological electronic bands in experimentally feasible materials, characterise existing quantum frustrated materials and connect these materials with minimal theoretical models. This project also aims to reveal further families of topological materials and clarify their physical properties.Read moreRead less
Rational Design of Novel Multiferroic Materials for Energy Harvesting and Energy Efficiency. Multiferroics are a class of fundamentally complex materials in which several ferroic orders (for example, ferroelectric and ferromagnetic) coexist. The coupling between their electric and magnetic degrees of freedom is controllable via stress and external fields, thus opening the possibility for breakthrough technological developments. By working at the frontier of complex nanostructured oxide materials ....Rational Design of Novel Multiferroic Materials for Energy Harvesting and Energy Efficiency. Multiferroics are a class of fundamentally complex materials in which several ferroic orders (for example, ferroelectric and ferromagnetic) coexist. The coupling between their electric and magnetic degrees of freedom is controllable via stress and external fields, thus opening the possibility for breakthrough technological developments. By working at the frontier of complex nanostructured oxide materials, this project aims to establish the rational basis for systematic design of novel artificially layered multiferroics, develop accurate and computationally affordable methods to simulate these materials under finite-temperature conditions, and exploit this knowledge to devise likely revolutionary photovoltaic, nanoelectronic and energy conversion applications.Read moreRead less
Magnonics with skyrmions. Skyrmions – nanoscale topologically protected spin textures, are considered as ideal candidates for encoding and transmitting bits of information. This burgeoning research field, however, suffers from the same limitations of all spintronic concepts – the high currents needed to move skyrmions. Magnonics is yet another emerging approach, which main aim is to investigate the behaviour of spin waves in magnetic nanostructures. In essence, spin waves are a propagating re-or ....Magnonics with skyrmions. Skyrmions – nanoscale topologically protected spin textures, are considered as ideal candidates for encoding and transmitting bits of information. This burgeoning research field, however, suffers from the same limitations of all spintronic concepts – the high currents needed to move skyrmions. Magnonics is yet another emerging approach, which main aim is to investigate the behaviour of spin waves in magnetic nanostructures. In essence, spin waves are a propagating re-ordering of the magnetisation and therefore use the least amount of power, making them perfect for driving skyrmions. This project fuses skyrmions with magnonics. The central goal is the formulation of model for the magnon assisted manipulation of skyrmions and their lattices.Read moreRead less
Novel 2-photon atom manipulation for ultra-nanoscale processing of diamond. There is intense interest in exploiting diamond's remarkable properties in many fields of science and technology, but fabricating and processing devices remains a major challenge. This project will build on previous work, using a recently discovered novel laser-induced surface phenomenon that enables, for the first time for any material, the exciting prospect of using light to manipulate surface atoms with atomic precis ....Novel 2-photon atom manipulation for ultra-nanoscale processing of diamond. There is intense interest in exploiting diamond's remarkable properties in many fields of science and technology, but fabricating and processing devices remains a major challenge. This project will build on previous work, using a recently discovered novel laser-induced surface phenomenon that enables, for the first time for any material, the exciting prospect of using light to manipulate surface atoms with atomic precision. This project aims to elucidate the mechanisms underpinning the optical interaction to reveal its full potential and use it to address key problems in diamond nano-device fabrication that lie beyond the reach of current techniques. It is expected that the outcomes will directly enhance Australia's current strengths in diamond-based quantum and photonic technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101147
Funder
Australian Research Council
Funding Amount
$407,600.00
Summary
First-principles design of atomic defects for quantum technologies. This project aims to address the issue of designing and engineering better single-photon sources based on atomic defects in solids, a crucial building block for many quantum technologies. Using advanced first-principles quantum mechanical theories and calculations, the project expects to produce fundamental knowledge of key mechanisms and properties, and to use this to inform the design of new atomic defects for tailored applica ....First-principles design of atomic defects for quantum technologies. This project aims to address the issue of designing and engineering better single-photon sources based on atomic defects in solids, a crucial building block for many quantum technologies. Using advanced first-principles quantum mechanical theories and calculations, the project expects to produce fundamental knowledge of key mechanisms and properties, and to use this to inform the design of new atomic defects for tailored applications as quantum emitters. The expected outcomes, including novel methodologies, will contribute to different research areas, from condensed matter and materials physics to quantum science and technology. This project should provide significant benefits in accelerating quantum technology innovation in Australia.Read moreRead less