Developmental Schizotypy In The General Population: Early Risk Factors And Predictive Utility.
Funder
National Health and Medical Research Council
Funding Amount
$830,952.00
Summary
This study will determine early childhood risk factors for psychosis-proneness in children aged 11 years, and emerging signs and symptoms of mental health disorders of these children, using population data from the NSW Child Development Study. Determining risk for psychosis as early as possible in the life course will enable the provision of preventative interventions to children at critical points in development.
Preventing Mental Health Problems In Children: A Population-based Cluster Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$431,133.00
Summary
14% of Australian children develop mental health problems. As treatment is time and cost intensive, prevention is the ideal model. This can be targeted to ‘at risk’ children, but may stigmatise families and have poor uptake. This project aims to trial whether a population targeted approach embedded in universal prevention performs better than targeted prevention alone, with each approach compared to ‘usual care’. The local and state government partners will ensure sustainability, policy relevanc ....14% of Australian children develop mental health problems. As treatment is time and cost intensive, prevention is the ideal model. This can be targeted to ‘at risk’ children, but may stigmatise families and have poor uptake. This project aims to trial whether a population targeted approach embedded in universal prevention performs better than targeted prevention alone, with each approach compared to ‘usual care’. The local and state government partners will ensure sustainability, policy relevance and uptake if effectiveRead moreRead less
Microfluidic Strategy For Circulating Tumour Cells Analysis In Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$429,180.00
Summary
My approach and ultimate goal over the next 4 years is to demonstrate the use of recently discovered “Nanoshearing” technology as a standard diagnostic tool for cancer patients undergoing systemic therapy and assess the impact of standard protocols in predicting response to therapy and patient outcomes. Data from this study could potentially define new standards of clinical practice, as they relate to follow-up screening for response to therapy and recurrence of disease.
Antibiotic resistance is a looming public health crisis. New antibiotics with new mechanisms of action are desperately needed. The long-term goal of this research is to develop new drugs that disarm bacteria to overcome the problem of antibiotic resistance.
Improving Global Tuberculosis Control With The AuTuMN Platform
Funder
National Health and Medical Research Council
Funding Amount
$655,059.00
Summary
Tuberculosis (TB) is the world’s leading infectious killer, with the failure of global control responsible for the vast majority of Australia’s cases. Using our robustly developed software platform, we have performed several country-level studies to predict the future burden of disease and compare the impact of alternative responses to controlling the epidemic. In this project, we will extend our platform to perform simulations at the global level and answer key questions in TB control.
The SAVE Trial: Securing All IntraVenous Devices Effectively In Hospitals. A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$980,393.00
Summary
Going to hospital usually means having an IV drip in your hand or arm vein. Almost half of all IV drips fall out or fail because they are not well secured to the skin. This means patients miss out on treatment and have additional painful needlesticks to insert new devices. Serious infections can also occur. This study will find the best dressings to use on IV drips. Patients will have their drips glued in with medical superglue, or have one of two new dressings, compared with current usual care.
Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the fin ....Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the findings will foster more effective and efficient responses. Additionally, the findings will inform victims of partner violence of risks related to escalation toward fatal outcomes and should facilitate help seeking behaviour. Collectively, project findings should expand understanding, improve service delivery and save lives.
Read moreRead less
Understanding and Costing Offending Trajectories: Creating an Evidence-Base for Targeting Crime Prevention. The research will provide an evidence-base for targeting diversionary and crime prevention programs and for assessing their cost-effectiveness. Many of these programs have resulted in a range of beneficial outcomes and they are receiving increased government funding. By providing a better understanding of offending pathways, the research will enable programs to be targeted towards particul ....Understanding and Costing Offending Trajectories: Creating an Evidence-Base for Targeting Crime Prevention. The research will provide an evidence-base for targeting diversionary and crime prevention programs and for assessing their cost-effectiveness. Many of these programs have resulted in a range of beneficial outcomes and they are receiving increased government funding. By providing a better understanding of offending pathways, the research will enable programs to be targeted towards particular at-risk groups at crucial developmental phases. The innovative longitudinal costing method that will be developed and applied in the Queensland context will enable an assessment of the cost-effectiveness of diversionary and crime prevention programs. This will provide a sound empirical basis for directing scarce government resources.Read moreRead less
The Effectiveness Of An Indicated Prevention Program For Anxiety
Funder
National Health and Medical Research Council
Funding Amount
$867,982.00
Summary
Generalised anxiety disorder (GAD) is a common disorder. In this research project, we evaluate the effectiveness of a new automated Internet program which is designed to reduce the risk of GAD and to promote self help. If found to be effective, this website will provide assistance to those at risk living in rural and remote areas without access to other resources, and individuals who prefer to seek help anonymously.