Translating Evidence-Based Psychological Interventions For Older Adults With Depression And Anxiety Into Public And Private Mental Health Settings Using A Stepped Care Framework
Funder
National Health and Medical Research Council
Funding Amount
$1,037,209.00
Summary
This project aims to evaluate the feasibility of implementing evidence based psychological interventions to treat geriatric depression and anxiety in real world (public and private) mental health settings. The outcomes of this research will provide important information about how to effectively translate evidence-based low intensity and moderate intensity interventions into routine care, and the cost benefits associated with such a model.
A Multi-ethnic Cohort And Intervention Trial To Identify Early Biomarkers For Type 2 Diabetes And Customise Individualized Environments For Disease Prevention
Funder
National Health and Medical Research Council
Funding Amount
$597,376.00
Summary
Diabetes is often called a lifestyle disease, however, large clinical studies have shown that diabetes cannot always be prevented through lifestyle modification. This collaborative study between Shanghai Institutes of Biological Science and Sydney University will identify biomarkers that predict the development of type 2 diabetes. Using this knowledge, the best interventions (including diet, exercise and medications) to improve an individual’s risk profile for type 2 diabetes will be identified.
DEVELOPMENT OF NOVEL THERAPEUTICS FOR DEMENTIA: Investigating Tailored Brain Stimulation Approaches For Dementia Prevention And Treatment.
Funder
National Health and Medical Research Council
Funding Amount
$723,105.00
Summary
Dementia is a debilitating and devastating illness impacting significantly on sufferers, carers and the wider community. Current treatment approaches are limited in their effectiveness and alternative therapeutics are needed. My research will investigate the use of brain stimulation techniques for the treatment and prevention of dementia.
Evidence For Suicide Prevention In Planning Transitions From Employment To Retirement In Older Age Populations
Funder
National Health and Medical Research Council
Funding Amount
$237,188.00
Summary
This study will investigate the impact of changes in employment status in older aged Australians on subsequent risk of suicidal behaviour, and the extent to which this risk is modified by referral pathways within mental health services and the role of other social supports.
LIFECYCLE - Early Life Stressors And LifeCycle Health
Funder
National Health and Medical Research Council
Funding Amount
$453,811.00
Summary
Early in life is a period of time during which we can institute changes that can have long lasting benefits for asthma, obesity, diabetes mellitus and mental and cardiovascular health. The current project, LIFECYCLE is a cooperative project with a combined total of a quarter of a million participants, which will be the definitive study to determine, which early life events should be modified for improving health trajectories throughout life.
Consumer Directed Care: Understanding And Promoting Participation And Care Outcomes For People Living With Dementia In Receipt Of A Home Care Package
Funder
National Health and Medical Research Council
Funding Amount
$571,648.00
Summary
This research will develop tools and assess the impact of the delivery of Consumer Directed Care for people living with dementia in receipt of a Home Care Package. It will also translate the findings into an intervention aimed at building the capacity of service providers and consumers to work together to improve care outcomes for people with dementia.
Genetic Investigations For Prodromal Alzheimer’s Disease
Funder
National Health and Medical Research Council
Funding Amount
$719,374.00
Summary
The disease process in Alzheimer’s disease (AD) begins decades before a diagnosis is made. We urgently need to investigate this pre-symptomatic stage to learn how the disease process begins, and allow the development of treatments that work before the brain is irreparably damaged. I will use genetic risk factors for AD to predict who is most at risk of developing AD. I will look for early changes and easily accessible markers, including the use of state of the art brain imaging.
Dengue is a viral infection that is transmitted by mosquitoes in tropical regions of the world, including in northern Australia. For doctors who treat dengue patients, a major unmet need is the ability to predict which patients will develop severe complications and need highly specialized supportive care. This proposal will seek to address this unmet need by examining whether markers of human genetic variation can be used to predict those patients at risk of severe dengue.
A European DNA Bank For Deciphering The Missing Heritability Of Alzheimer's Disease (EADB)
Funder
National Health and Medical Research Council
Funding Amount
$1,556,995.00
Summary
Understanding the genetics of Alzheimer’s disease (AD) is one of the best ways of improving our knowledge of the underlying mechanisms of disease development. There is evidence that genetic factors account for up to 80% of the risk for AD. Recent advances in genetics still explain <50% of this risk. This proposal will help two major Australian studies to partner with a large European consortium in trying to understand the “missing” heritability, using existing and novel genetic data.