Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.
POPULATION-LEVEL RELEVANCE OF RISK FACTORS FOR CANCER
Funder
National Health and Medical Research Council
Funding Amount
$319,692.00
Summary
This research will provide novel up-to-date evidence-based information on the population-level relevance of lifestyle-related risk factors for cancer in Australia, by applying an advanced disease burden measure to established Australian cohort studies. This knowledge on the national cancer burden is essential for targeting cancer interventions for those at highest risk and evaluating their effectiveness.
Deaths In Young People Involved In The Youth Justice System: Towards Evidence-based Prevention
Funder
National Health and Medical Research Council
Funding Amount
$620,705.00
Summary
Young offenders have complex health needs and are at dramatically increased risk of preventable death due to drug overdose, suicide and injury. In order to inform effective prevention, a more detailed understanding of mortality in these young people is required. This project will examine all deaths in young offenders in Queensland from 1993 to 2015, identify targets for prevention, and recommend policy reforms and interventions that are supported by evidence and are culturally appropriate.
Evidence-based Recommendations For Interpregnancy Intervals In High-income Countries
Funder
National Health and Medical Research Council
Funding Amount
$423,305.00
Summary
This study will identify the optimal and harmful interpregnancy intervals for a range of maternal and child outcomes in three high-income countries. With a study population of more than 7.5 million births and a longitudinal study design that matches pregnancies to the same women, this study will inform new interpregnancy interval recommendations for high-income countries that will lead to a reduction in avoidable excess morbidities attributable to uninformed pregnancy planning.
Implications Of The Increasing Duration Of Life Spent With Obesity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$251,830.00
Summary
As the prevalence of obesity at younger ages increases, people are living longer with obesity. We have recently shown that this has an increased risk of mortality and diabetes. In this project we will look at the extent to which an increasing length of time lived with obesity is also associated with increased risks of hypertension, heart disease, cancer, arthritis and disability. We will also look at the effect of this increasing duration on the overall health of Australian adults.
Preventing Mortality In Adults After Release From Prison: Advancing Global Knowledge Through An International, Individual Participant Data Meta-analysis
Funder
National Health and Medical Research Council
Funding Amount
$613,687.00
Summary
Ex-prisoners are at increased risk of death, but not enough is known about the incidence, timing, causes, context or risk factors for preventable death in this population. In this project we have compiled 18 cohorts of ex-prisoners (total number=1,159,290) and will analyse the data to determine exactly which ex-prisoners are at the greatest risk from what, and when. This new knowledge will inform policy changes to reduce the unnecessary loss of life in this vulnerable population.
Temporal Trends In The Incidence, Site And Survival Of Metastatic Breast Cancer In Australia
Funder
National Health and Medical Research Council
Funding Amount
$190,494.00
Summary
There have been major advances in breast cancer treatment over the last decade. This project will use information collected from the NSW cancer registry and hospitals to report on changes in the type and risk of breast cancer spread and survival for women with a new diagnosis of breast cancer before and after new treatments introduced since 2005. This information is essential for doctors to provide women with up-to-date information; and for planning appropriate health services and research.
Biological, Phenotypic And Public Health Costs Of Risk And Protective Pathways To Non-communicable Disease In Children And Adults: The National Longitudinal Study Of Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$1,521,590.00
Summary
Although a late event for most Australians, chronic diseases present a crippling burden for Australia. This project explores their early roots, before overt disease emerges, in 3500 parents and their children in the Longitudinal Study of Australian Children. We will measure how accumulated stress and buffering characteristics play out in the biology of cell ageing and inflammation, in developing heart, lung, kidney and bone health, and in quality of life and health costs to the population.
HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Recent Changes In IVF Clinical Practice: Data Linkage To Investigate Their Impact On Fetal Growth And Birth Defects.
Funder
National Health and Medical Research Council
Funding Amount
$219,076.00
Summary
In Australia 1 in 25 births are conceived from IVF treatment and this is increasing with the continuing trend towards later childbearing. This study will use linked population data to assess fetal growth and birth defects in IVF-conceived children following major changes to IVF practice in the last decade. There are limited data internationally on health outcomes following the use of more recent IVF techniques and insufficient data to allow for adequate pre-treatment counselling.