Advanced Materials from Automated Synthesis of Sequence-Defined Polymers. The project aims to develop industrially scalable and environmentally friendly methods for synthesis of sequence-defined multiblock copolymers (polymer chains containing segments of different polymer types) using automated synthesis methods. The materials to be explored will be largely based on renewable biomass-derived monomeric building blocks. Such polymers are able to undergo microphase separation into spatially period ....Advanced Materials from Automated Synthesis of Sequence-Defined Polymers. The project aims to develop industrially scalable and environmentally friendly methods for synthesis of sequence-defined multiblock copolymers (polymer chains containing segments of different polymer types) using automated synthesis methods. The materials to be explored will be largely based on renewable biomass-derived monomeric building blocks. Such polymers are able to undergo microphase separation into spatially periodic compositional patterns, thereby providing access to a vast range of nano-engineered materials. This would enable design and synthesis of new advanced materials, making use of renewable resources and supporting the circular economy, with diverse potential applications ranging from nanomedicine to materials science.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL200100124
Funder
Australian Research Council
Funding Amount
$3,372,617.00
Summary
Very small nanoparticles made to measure. The administration of therapeutic drugs is often unsuccessful as the drug is quickly cleared from the body. Nanoparticles have been shown to enhance the efficiency of the drug administration, as evidenced by the increasing number of nanoformulations on the market, although commercially available products have currently a range of shortcomings, some of them related to their size. This research program aims to develop a toolset that allows the design of ve ....Very small nanoparticles made to measure. The administration of therapeutic drugs is often unsuccessful as the drug is quickly cleared from the body. Nanoparticles have been shown to enhance the efficiency of the drug administration, as evidenced by the increasing number of nanoformulations on the market, although commercially available products have currently a range of shortcomings, some of them related to their size. This research program aims to develop a toolset that allows the design of very small nanoparticles that display enhanced biological activity. The outcome will be an in-depth understanding of the relationship between polymer structure and properties, which is not only important for nanomedicine, but other areas such as catalysis and sensors. Read moreRead less
Stereolithographic Additive Manufacturing of Semicrystalline Thermoplastics. This project aims to advance the development of high-throughput stereolithographic additive manufacturing of thermoplastic polymers and composites by employing a multi-colour irradiation schemes in conjunction with photopolymerisable, ring-opening monomer resin formulations. The fundamental scientific understanding, engineering expertise, and concomitant technology advances generated by this project are anticipated to e ....Stereolithographic Additive Manufacturing of Semicrystalline Thermoplastics. This project aims to advance the development of high-throughput stereolithographic additive manufacturing of thermoplastic polymers and composites by employing a multi-colour irradiation schemes in conjunction with photopolymerisable, ring-opening monomer resin formulations. The fundamental scientific understanding, engineering expertise, and concomitant technology advances generated by this project are anticipated to enable additive manufacturing to transition from the rapid prototyping of individual, unique items to the high volume production of robust, reprocessable plastic parts. By obviating the large capital expense of conventional fabrication, this developed technology should provide a path to reinvigorate Australian manufacturing.Read moreRead less
Photochemical Design of Microstructured Aerospace Materials. Commercial aviation and shipping spend over US$300 billion on fuel and emit almost 3 billion tonnes of carbon dioxide annually at an enormous environmental cost. This project will provide the material chemistry innovation basis for the production of drag reduction surfaces that can be applied to enable a more effective airflow over an aircraft, thus reducing fuel consumption. Critically, the material design approach will not only deliv ....Photochemical Design of Microstructured Aerospace Materials. Commercial aviation and shipping spend over US$300 billion on fuel and emit almost 3 billion tonnes of carbon dioxide annually at an enormous environmental cost. This project will provide the material chemistry innovation basis for the production of drag reduction surfaces that can be applied to enable a more effective airflow over an aircraft, thus reducing fuel consumption. Critically, the material design approach will not only deliver a high performance coating for the production of drag reduction surfaces, but allow these surfaces to be tailored to specific application profiles including UV resistance and anti-fouling properties. The project will place an Australian company at the forefront of drag reduction technologyRead moreRead less
Programming the Microstructure of 3D Printed Objects . This project aims to apply state-of-the-art living polymerisation techniques to 3D printing to efficiently produce customised polymer materials that are tailored at the molecular level. By combining computational modeling and experimental approach, fast and oxygen tolerant photoliving radical polymerisation will be developed and applied to 3D printing. These new systems will produce highly structured polymer materials with remarkable mechani ....Programming the Microstructure of 3D Printed Objects . This project aims to apply state-of-the-art living polymerisation techniques to 3D printing to efficiently produce customised polymer materials that are tailored at the molecular level. By combining computational modeling and experimental approach, fast and oxygen tolerant photoliving radical polymerisation will be developed and applied to 3D printing. These new systems will produce highly structured polymer materials with remarkable mechanical properties. The effect of nanostructure on the macroscopic material properties will be investigated. The intended outcome of this project will produce advanced materials with tailored mechanical properties via streamlined and accessible approaches.Read moreRead less
Precision-built dynamic and functional polymer vesicles. The project aims to create new precision-built polymer vesicles with controlled size, stability, functionality and environmental responsiveness to mimic some of the key dynamic functions of the cell. The project expects to generate new knowledge on the dynamic interplay between the polymer and its bilayer including on-demand activated polymerisations and reactions, logic gates and in situ sensors. Expected outcomes of this project include ....Precision-built dynamic and functional polymer vesicles. The project aims to create new precision-built polymer vesicles with controlled size, stability, functionality and environmental responsiveness to mimic some of the key dynamic functions of the cell. The project expects to generate new knowledge on the dynamic interplay between the polymer and its bilayer including on-demand activated polymerisations and reactions, logic gates and in situ sensors. Expected outcomes of this project include new synthetic polymer techniques and new quantitative insights into the role of compartmentalisation on chemical reactions and polymerisations. This project will provide fundamental knowledge on bio/polymer vesicles with great potential to advance the polymer industry in Australia.Read moreRead less
Chiral synthetic macromolecules - control of sequence and stereochemistry. This project aims to assemble a library of novel chiral polymers mimicking natural peptides with precisely controlled primary structures using emerging synthetic technologies. A systematic investigation of these synthetic materials will provide an in-depth understanding of how sequence and stereochemistry influence chemical and physical properties. Employing rational design principles, desired functionality could be optim ....Chiral synthetic macromolecules - control of sequence and stereochemistry. This project aims to assemble a library of novel chiral polymers mimicking natural peptides with precisely controlled primary structures using emerging synthetic technologies. A systematic investigation of these synthetic materials will provide an in-depth understanding of how sequence and stereochemistry influence chemical and physical properties. Employing rational design principles, desired functionality could be optimised through the selective modification of polymer structure. These materials should be able to emulate the unique properties and functionality of natural peptides/proteins, making them invaluable for biochemical applications, such as molecular recognition and asymmetric catalysis.Read moreRead less
Sequence-Defined Polymers with Optical Information Readout. The project aim is to introduce the first optically readable sequence-defined polymers based on fluorophore excimers, whose information content can be read as simply as conventional barcodes. These macromolecular barcodes, embedded in solid polymer matrices, will overcome the current limitations of reading information from synthetic macromolecules. An interdisciplinary effort will fuse chemistry, law, and criminology to develop the tec ....Sequence-Defined Polymers with Optical Information Readout. The project aim is to introduce the first optically readable sequence-defined polymers based on fluorophore excimers, whose information content can be read as simply as conventional barcodes. These macromolecular barcodes, embedded in solid polymer matrices, will overcome the current limitations of reading information from synthetic macromolecules. An interdisciplinary effort will fuse chemistry, law, and criminology to develop the technology in ways that are expected to address illicit plastic waste trafficking – ending the anonymity of polymer waste by creating a regulatory and criminological paradigm for tracing plastic waste to hold actors in the value chain responsible.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101096
Funder
Australian Research Council
Funding Amount
$427,098.00
Summary
Programming Polymer Function via Ring-opening Polymerisation of Peptides. The project aims to set the foundation of a class of intelligent polymers, whose structure and function – including catalytic activity and biodegradability – can be readily programmed. In contrast to well-established radical polymerization techniques leading to all-carbon based backbones, the outlined research will develop technologies to incorporate short peptides into the backbones of synthetic polymers. The syntheticall ....Programming Polymer Function via Ring-opening Polymerisation of Peptides. The project aims to set the foundation of a class of intelligent polymers, whose structure and function – including catalytic activity and biodegradability – can be readily programmed. In contrast to well-established radical polymerization techniques leading to all-carbon based backbones, the outlined research will develop technologies to incorporate short peptides into the backbones of synthetic polymers. The synthetically adjustable amino acid sequence of the main chain embedded peptides will translate into the structure and function of the modular polymer. The DECRA will deliver unprecedented access towards tailor-made mechanical properties, catalytic activity and biodegradability of polymeric materials.Read moreRead less
MOF-polymer 3D composites for liquid organic hydrogen carrier utilisation. This project aims to address the hydrogen transportation challenge by utilising liquid organic hydrogen carriers rather than other techniques involving high pressures or cryogenic temperatures that need complex infrastructure. This project expects to generate knowledge in the hydrogen economy area using the novel approach of simplifying the separation of the liquid carriers before and after their release of hydrogen. Expe ....MOF-polymer 3D composites for liquid organic hydrogen carrier utilisation. This project aims to address the hydrogen transportation challenge by utilising liquid organic hydrogen carriers rather than other techniques involving high pressures or cryogenic temperatures that need complex infrastructure. This project expects to generate knowledge in the hydrogen economy area using the novel approach of simplifying the separation of the liquid carriers before and after their release of hydrogen. Expected outcomes of this project include largely enhanced hydrogen transportation efficiency by recently discovered new materials. This should provide significant benefits such as a huge economic opportunity for Australia, both for domestic low cost clean energy, and for export to Asia in the hydrogen economy.Read moreRead less