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Scheme : Early Career Fellowships
Research Topic : placental blood flow
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Cardiology (incl. Cardiovascular Diseases) (4)
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  • Funded Activity

    A Study Of The Cardiovascular Effects Of Sulfonylureas With Particular Emphasis On Coronary Vasoreactivity, Atherogenesi

    Funder
    National Health and Medical Research Council
    Funding Amount
    $445,552.00
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    Funded Activity

    Effects Of Exercise On Gastrointestinal Function And Postpranadial Blood Pressure In The Elderly

    Funder
    National Health and Medical Research Council
    Funding Amount
    $56,003.00
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    Funded Activity

    The Role Of Purinergic Receptors In The Development Of Diabetic Retinopathy.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $382,009.00
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    Funded Activity

    Assessment Of Remote Ischemic Conditioning On Post-cardiac Arrest Myocardial Dysfunction By Magnetic Resonance Imaging, Invasive Coronary Hemodynamic Measurements And Markers Of Inflammation

    Funder
    National Health and Medical Research Council
    Funding Amount
    $265,881.00
    Summary
    Cardiac arrest and heart attack continue to cause unacceptably high mortality and morbidity. Even following successful resuscitation many people do not recover due to the inflammation caused by a lack of blood flow. We will investigate remote ischemic conditioning, utilizing a combination of world class imaging with heart MRI, flow monitors directly in heart arteries and markers of inflammation, We aim to determine the impact and recovery to the heart, brain and circulation of this new therapy.
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    Funded Activity

    Influence Of Intra-luminal Pressure On Pulmonary Haemodynamics In Fetal Sheep

    Funder
    National Health and Medical Research Council
    Funding Amount
    $350,508.00
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    Funded Activity

    Neuro-protection In The Preterm Brain - A New Role For Dopamine Therapy?

    Funder
    National Health and Medical Research Council
    Funding Amount
    $183,975.00
    Summary
    Brain injury in premature babies leads to long term adverse outcome. Preliminary data show that dopamine improves brain oxygen. Our study will define effects of dopamine in preventing injury in the immature brain, using animal studies. In immature lambs receiving dopamine, we will test the protective effect of dopamine on brain oxygenation during hypoxia. Outcome will be measured by examining cell injury on lamb brain slices.
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    Funded Activity

    Studying Coronary Physiology Within Human Coronary Arteries Using Computational Fluid Dynamics

    Funder
    National Health and Medical Research Council
    Funding Amount
    $383,834.00
    Summary
    The aim of this project is to combine the recent technological advances within the individual fields of coronary physiology, three-dimensional coronary angiography, and computational fluid dynamics to develop a novel method to calculate realistic coronary blood flow. This technique will provide a simple and clinically applicable method to measure physiological parameters such as microcirculatory resistance and shear stress within _live� human coronary arteries.
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    Funded Activity

    Assessment Of Microcirculatory Impairment In Reperfused Acute Myocardial Infarction By Invasive Coronary Hemodynamic Measurements And Cardiac Magnetic Resonance Imaging: Modulation By Exenatide

    Funder
    National Health and Medical Research Council
    Funding Amount
    $388,752.00
    Summary
    This study aims to assess the health of small blood vessels of the heart muscle during and following a heart attack by measuring blood flow with a pressure wire and with cardiac magnetic resonance imaging. Small blood vessels within the heart muscle may become injured due to lack of oxygen and white cell activation during a heart attack. This study investigates the effect of a new agent, exenatide, on small blood vessels and white cells and determines whether it might lessen the degree of damage .... This study aims to assess the health of small blood vessels of the heart muscle during and following a heart attack by measuring blood flow with a pressure wire and with cardiac magnetic resonance imaging. Small blood vessels within the heart muscle may become injured due to lack of oxygen and white cell activation during a heart attack. This study investigates the effect of a new agent, exenatide, on small blood vessels and white cells and determines whether it might lessen the degree of damage to heart muscle and small blood vessels.
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    Funded Activity

    Insulin Resistance In Peripheral Artery Disease: Clinical Significance And Therapy

    Funder
    National Health and Medical Research Council
    Funding Amount
    $316,449.00
    Summary
    This project seeks to improve our understanding and treatment of peripheral artery disease – a condition caused by narrowing/blockages in arteries that supply the legs. Peripheral artery disease affects ~15% of adults >40 years and often causes severe, disabling leg pains during walking. Building on recent findings that peripheral artery disease shares some similar characteristics to type 2 diabetes (“insulin resistance”), a common anti-diabetes drug will be trialled as a potential new strate .... This project seeks to improve our understanding and treatment of peripheral artery disease – a condition caused by narrowing/blockages in arteries that supply the legs. Peripheral artery disease affects ~15% of adults >40 years and often causes severe, disabling leg pains during walking. Building on recent findings that peripheral artery disease shares some similar characteristics to type 2 diabetes (“insulin resistance”), a common anti-diabetes drug will be trialled as a potential new strategy to alleviate these leg pains.
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    Funded Activity

    Placental Function Testing To Prevent Stillbirths

    Funder
    National Health and Medical Research Council
    Funding Amount
    $414,768.00
    Summary
    Stillbirth is a global public health problem affecting 3 million babies annually. In Australia, almost 3,000 stillbirths occur each year, many of which are preventable if the pregnancy is recognised as being at risk. This fellowship will develop novel non-invasive techniques to identify these at risk pregnancies using biomarkers in the mother's blood and cutting edge imaging. The efficacy of these novel techniques to prevent stillbirths and improve pregnancy outcomes will then be assessed.
    More information

    Showing 1-10 of 31 Funded Activites

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