Improving Conservative Management Of Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$763,409.00
Summary
Osteoarthritis (OA), commonly involving the knee joint, is a major public health problem worldwide. This Fellowship aims to reduce the burden of knee OA by research to improve patient outcomes through more effective and accessible conservative non-drug care that takes a biopsychosocial approach and emphasises patient self-management. It will also build research capacity in the field through training and mentoring early career researchers.
Prof. Herbert conducts clinical research into the effectiveness of physiotherapy interventions. A focus of this research is study of the effectiveness of stretch-based interventions for prevention and treatment of contracture. His clinical research is backed by a program of laboratory research investigating the mechanical properties of human muscles.
I conduct research in physiotherapy, especially physiotherapy treatments for muscle contracture. Over the next 5 years I will investigate mechanisms of normal muscle growth and muscle contracture in adults with stroke and children with cerebral palsy. I will also conduct clinical studies investigating prophylaxis for haemophilia, prevention of complications after spinal cord injury, and multi-level surgery for contracture in children with cerebral palsy.
Over 80 million people have chronic constipation. It affects over 1/5 older people and is a major problem in aged-care. We have found that a painless method of electrical stimulation across the abdomen can overcome chronic constipation in children and adults. We will test the method to see what types of constipation it can help, including constipation caused by pain-medication and irritable bowel syndrome. This treatment is given at home and could improve life for many people around the world.
Physiology And Pathophysiology Of Disorders Of The Musculoskelatal System
Funder
National Health and Medical Research Council
Funding Amount
$926,980.00
Summary
This application for a Senior Principal Research Fellowship is to enable me to address the enormous burden of musculoskeletal conditions - an important, but understudied and underfunded area of health/medical research. My focus is the most costly and prevalent musculoskeletal conditions of low back pain and osteoarthritis, and other neuromuscular conditions such as incontinence. My aim is to improve outcomes by discovering how to apply the right treatment to the right person at the right time.
Chronic pain afflicts 1 in 5 Australians; it is one of our most expensive health care problems. Prof Moseley's research asks: (1) Why do some people get chronic pain but others don't? (ii) How can we treat chronic pain so sufferers can return to a meaningful, productive and comfortable life? (iii) How can we stop chronic pain from developing in the first place? His research involves behavioural and physiological experiments in humans, that lead to new treatments, which are tested in clinical tri ....Chronic pain afflicts 1 in 5 Australians; it is one of our most expensive health care problems. Prof Moseley's research asks: (1) Why do some people get chronic pain but others don't? (ii) How can we treat chronic pain so sufferers can return to a meaningful, productive and comfortable life? (iii) How can we stop chronic pain from developing in the first place? His research involves behavioural and physiological experiments in humans, that lead to new treatments, which are tested in clinical trials.Read moreRead less
Stroke affects 1 in 6 Australians and often leads to lifelong disability. This Fellowship will support A/Prof Bernhardt to: 1) complete the world first, international clinical trial of very early rehabilitation for people with stroke (AVERT), which has the potential to reduce the global disability burden of this disease; 2) in a new acute exercise laboratory, complete studies that help refine existing early exercise interventions and 3) test new models of rehabilitation care that take advantage ....Stroke affects 1 in 6 Australians and often leads to lifelong disability. This Fellowship will support A/Prof Bernhardt to: 1) complete the world first, international clinical trial of very early rehabilitation for people with stroke (AVERT), which has the potential to reduce the global disability burden of this disease; 2) in a new acute exercise laboratory, complete studies that help refine existing early exercise interventions and 3) test new models of rehabilitation care that take advantage of advanced e-health capability.Read moreRead less
Physiology And Pathophysiology Of Disorders Of The Musculoskelatal System
Funder
National Health and Medical Research Council
Funding Amount
$898,008.00
Summary
I am a neuroscientist and physiotherapist focussed on the conservative management of disorders of the musculoskeletal system. My research aims to uncover the mechanisms underlying musculoskeletal pain and other disorders such as incontinence, to develop and refine treatments for these conditions, and to understand the mechanism for efficacy of these treatments.
Promoting Recovery After Neurotrauma: Basic Science, Clinical Trials And Community Engagement
Funder
National Health and Medical Research Council
Funding Amount
$356,269.00
Summary
To promote recovery after neurotrauma by controlling the spread of damage and by maximising function in surviving circuits. The work involves animal models & nanotechnology as well as clinical rehabilitation trials in humans with spinal cord injury.