A hierarchical quantum mechanical and classical simulation of biological ion channels. I aim to develop a methodology incorporating molecular quantum
mechanics and classical Brownian mechanics in a way that can be
applied practically to large macromolecular systems, thus relating
fine structural details to experimentally measurable
properties. Specifically, I will apply this methodology to study ion
channels in which the challenge is to relate electronic and atomic
structure to the conduct ....A hierarchical quantum mechanical and classical simulation of biological ion channels. I aim to develop a methodology incorporating molecular quantum
mechanics and classical Brownian mechanics in a way that can be
applied practically to large macromolecular systems, thus relating
fine structural details to experimentally measurable
properties. Specifically, I will apply this methodology to study ion
channels in which the challenge is to relate electronic and atomic
structure to the conductance properties of the channel. Accurately
determining these relationships provides a pathway to developing cures
for many neurological, cardiac, and muscular diseases.
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The evolution of mass and energy over the past 13 billion years. The universe has slowly transformed atomic material into a range of structures from planets, stars, galaxies, clusters and filaments. In the process the universe has generated energy at almost all wavelengths. This project will build a model to explain the evolution of mass, energy and structure in the universe and will test the model using the latest data.
Utilising artificial intelligence to elucidate the physics of galaxies. For decades astronomers have puzzled over the connection between the structure and evolution of galaxies and the role played by host environments. This project aims to resolve this problem by combining multi-wavelength observations, multi-component simulations, and pioneering data analysis using artificial intelligence. In particular, we target the nearby Fornax galaxy cluster as a laboratory for studying galaxy formation in ....Utilising artificial intelligence to elucidate the physics of galaxies. For decades astronomers have puzzled over the connection between the structure and evolution of galaxies and the role played by host environments. This project aims to resolve this problem by combining multi-wavelength observations, multi-component simulations, and pioneering data analysis using artificial intelligence. In particular, we target the nearby Fornax galaxy cluster as a laboratory for studying galaxy formation in dense environments. Using our novel machine learning techniques, we will elucidate the physical mechanisms that drive the rapid evolution of star formation, galactic nuclei, and gas and dust content within Fornax. Our predictions will benefit ongoing and future surveys at the national and international level. Read moreRead less
Atomic Ionization on the Attosecond Time Scale. Electrons emit light, carry electric current, and bind atoms together to form molecules. Insight into their atomic-scale motion is the key to understanding the functioning of biological systems, developing efficient sources of x-ray light, and speeding up electronics. Capturing this electron motion requires attosecond (one quintillionth of a second) time resolution. Our research aims to understand and accurately model fundamental atomic processes ....Atomic Ionization on the Attosecond Time Scale. Electrons emit light, carry electric current, and bind atoms together to form molecules. Insight into their atomic-scale motion is the key to understanding the functioning of biological systems, developing efficient sources of x-ray light, and speeding up electronics. Capturing this electron motion requires attosecond (one quintillionth of a second) time resolution. Our research aims to understand and accurately model fundamental atomic processes taking place on the attosecond time scale. This research project will further enhance our reputation in an area where Australian theorists are preeminent, and the research training will produce PhD graduates with the skills essential in a multitude of nano-technology applications. Read moreRead less
Carbon nanotube fluidic channels for desalination - interplay of nanoscale confinement and electrostatics. Tiny tubes of carbon, ten thousand times smaller than human hair, allow water to pass through at extraordinary speed. This project aims to understand and improve their salt rejection properties using comprehensive experimental and theoretical approaches. This will provide the impetus and knowledge for developing advanced membranes for desalination
The effect of de-gassing on the dispersion and stability of emulsions and colloidal solutions. Although it is widely accepted that oil and water will not mix, the reverse has recently been found to occur (by the applicant) under the unusual conditions of complete de-gassing. This discovery has opened up new areas for investigation and for the development of new processes and products. Hydrocarbon oils and hydrophobic powders can now be readily dispersed in water without the use of additives. Ho ....The effect of de-gassing on the dispersion and stability of emulsions and colloidal solutions. Although it is widely accepted that oil and water will not mix, the reverse has recently been found to occur (by the applicant) under the unusual conditions of complete de-gassing. This discovery has opened up new areas for investigation and for the development of new processes and products. Hydrocarbon oils and hydrophobic powders can now be readily dispersed in water without the use of additives. However, the mechanisms involved have not yet been elucidated and it is the aim of this project to understand the process and develop potential commercial applications.Read moreRead less
Solving the mystery of ultra luminous fast radio burst emission . Fast Radio Bursts are a recently discovered inexplicable astronomical phenomenon whose millisecond-timescale emission is generated by regions less than 300 kilometres across yet so luminous it is visible at cosmological distances. Using the Australian Square Kilometre Array Pathfinder we have already localised these bursts, which made the front cover of Science, and recently used them to find the missing baryonic matter in the Uni ....Solving the mystery of ultra luminous fast radio burst emission . Fast Radio Bursts are a recently discovered inexplicable astronomical phenomenon whose millisecond-timescale emission is generated by regions less than 300 kilometres across yet so luminous it is visible at cosmological distances. Using the Australian Square Kilometre Array Pathfinder we have already localised these bursts, which made the front cover of Science, and recently used them to find the missing baryonic matter in the Universe. Next, we will scrutinise these bursts at three nanosecond time resolution, reaching the timescale necessary to probe the mechanism by which their ultra-luminous radiation is generated. This project will reveal previously inaccessible properties of the radiation to unlock the secrets of how they are produced.Read moreRead less
Weighing the Universe using fast radio bursts. Fast radio bursts are a newly-discovered astronomical phenomenon whose millisecond-timescale emission occurs at cosmological distances, rendering them exceptional probes of the matter that lies in intergalactic space. This project aims to measure the positions and obtain the distances to these bursts to make a direct measurement of the density of ordinary matter in the Universe, at least 50 per cent of which is believed to remain undetected in inter ....Weighing the Universe using fast radio bursts. Fast radio bursts are a newly-discovered astronomical phenomenon whose millisecond-timescale emission occurs at cosmological distances, rendering them exceptional probes of the matter that lies in intergalactic space. This project aims to measure the positions and obtain the distances to these bursts to make a direct measurement of the density of ordinary matter in the Universe, at least 50 per cent of which is believed to remain undetected in intergalactic space. This project will measure the distribution of this missing matter, and find how it has evolved throughout the history of the Universe. This will provide significant benefits, such as addressing two fundamental questions about our Universe: how much matter does it contain, and has a large fraction of it hitherto evaded detection in intergalactic space?Read moreRead less
Ocean Acidification in a Rapidly Increasing CO2 World. Carbon dioxide not only acts as a greenhouse gas but is being dissolved at increasing rates into the surface waters of the world's oceans, causing ocean acidity. We will examine how the rapidly increasing trend towards acidity in the oceans surrounding Australia is effecting the ability of marine organisms to calcify and determine the rate at which the world's ocean sink for CO2 is being reduced. New constraints will be placed on the critica ....Ocean Acidification in a Rapidly Increasing CO2 World. Carbon dioxide not only acts as a greenhouse gas but is being dissolved at increasing rates into the surface waters of the world's oceans, causing ocean acidity. We will examine how the rapidly increasing trend towards acidity in the oceans surrounding Australia is effecting the ability of marine organisms to calcify and determine the rate at which the world's ocean sink for CO2 is being reduced. New constraints will be placed on the critical threshold limits of CO2 emissions for sustainable calcification in both shallow tropical and deep-water marine ecosystems of the Southern Oceans.Read moreRead less
Detecting cosmic rays using precision radio imaging. This project's aim is to identify the source of the highest-energy particles in nature, cosmic rays, and discover new physical processes at energies unreachable by the Large Hadron Collider.
It will do this by using the Murchison Widefield Array radio telescope to detect the sub-microsecond pulses from cosmic ray interactions in the Earth's atmosphere. The project's intended outcome is a sample of thousands of cosmic ray events, and a new tec ....Detecting cosmic rays using precision radio imaging. This project's aim is to identify the source of the highest-energy particles in nature, cosmic rays, and discover new physical processes at energies unreachable by the Large Hadron Collider.
It will do this by using the Murchison Widefield Array radio telescope to detect the sub-microsecond pulses from cosmic ray interactions in the Earth's atmosphere. The project's intended outcome is a sample of thousands of cosmic ray events, and a new technique to analyse the structure within them.
The anticipated benefits are the establishment of the Murchison Widefield Array as a world-leading instrument for astroparticle physics, new knowledge of high-energy astro and particle physics, and advances and training in fast signal processing methods.Read moreRead less