The Origin and Evolution of the Animal Phyla inferred from Analysis of Multiple-Gene Data. Australia has recently begun an extensive research programme in the genomics of our flora and fauna. The enormous amounts of data that emerge from such research are highly complex, but they hold the key to understanding how biological organisms change over time. Our research will untangle that data to answer fundamental, unanswered questions in modern science: How did the animal groups originate? How are ....The Origin and Evolution of the Animal Phyla inferred from Analysis of Multiple-Gene Data. Australia has recently begun an extensive research programme in the genomics of our flora and fauna. The enormous amounts of data that emerge from such research are highly complex, but they hold the key to understanding how biological organisms change over time. Our research will untangle that data to answer fundamental, unanswered questions in modern science: How did the animal groups originate? How are they related to each other? How is biodiversity changing? The answers to these questions and the new analytical tools we will develop will put Australia firmly on the international "map" of Bioinformatics.Read moreRead less
Analysing and modelling molecular rate variation among nuclear and mitochondrial genomes. My research will have important practical benefits for bioinformaticians and evolutionary biologists, because existing analytical methods will be rigorously tested and new tools will be developed. Australia has a comparatively high concentration of researchers in this field, so my research will foster domestic collaboration and import international expertise. The research will provide important insights int ....Analysing and modelling molecular rate variation among nuclear and mitochondrial genomes. My research will have important practical benefits for bioinformaticians and evolutionary biologists, because existing analytical methods will be rigorously tested and new tools will be developed. Australia has a comparatively high concentration of researchers in this field, so my research will foster domestic collaboration and import international expertise. The research will provide important insights into the rates and patterns of genetic changes associated with domestication, and into variation in evolutionary rates among the primate ancestors of humans. In addition to developing new software, which will be made publicly available, I will develop new evolutionary models to supplement existing software packages. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100003
Funder
Australian Research Council
Funding Amount
$387,373.00
Summary
The evolution of venom and its role in shaping biodiversity. This project aims to study how venom, nature's most powerful weapon, evolves and shapes biodiversity. Using the iconic Australian and New Guinean venomous snakes as a model, this project expects to develop a novel approach to profile venom composition from museum specimens, test competing hypotheses on the evolution of venoms, and test for the association between the evolution of venoms and the evolution of diversity in species richnes ....The evolution of venom and its role in shaping biodiversity. This project aims to study how venom, nature's most powerful weapon, evolves and shapes biodiversity. Using the iconic Australian and New Guinean venomous snakes as a model, this project expects to develop a novel approach to profile venom composition from museum specimens, test competing hypotheses on the evolution of venoms, and test for the association between the evolution of venoms and the evolution of diversity in species richness and morphology. Expected outcomes include the largest venom database for any animal group and a better understanding of how venoms evolve and what role they play in earth’s biodiversity. The generated venom data has potential to be used in future studies to aid in the development of anti-venoms and drugs.Read moreRead less
Improving access to phylogenomic resources for under-resourced species: a new look at existing tools. This project will have an impact on our understanding of how to most effectively use existing genomic resources to benefit a wider range of species and to better design new genomic resources. By doing so, improved access to genomic resources will be provided to species that currently have few options.
Uncovering the evolutionary history of Australasian marsupials: combining molecular phylogenetics and ecological inference. Marsupials are symbolic of the uniqueness of Australia's biological systems and there is widespread public interest in their natural history. Yet we know little of the evolutionary mechanisms that have shaped their biodiversity. This is a critical problem when considered in the context of Australian marsupials having suffered the highest extinction rate of any continental m ....Uncovering the evolutionary history of Australasian marsupials: combining molecular phylogenetics and ecological inference. Marsupials are symbolic of the uniqueness of Australia's biological systems and there is widespread public interest in their natural history. Yet we know little of the evolutionary mechanisms that have shaped their biodiversity. This is a critical problem when considered in the context of Australian marsupials having suffered the highest extinction rate of any continental mammal fauna over the past 200 years. This project will make a major contribution to understanding the origins, timescale and ecological nature of Australasian marsupial evolution. In doing so, it will inform conservation strategy, promote Australasian marsupials as a model system for studying faunal coevolution and develop widely applicable bioinformatic tools.Read moreRead less
Evolutionary history and conservation of an iconic Australian plant group. This project aims to strengthen biodiversity conservation using evolutionary biology. By using new DNA sequencing technologies the project aims to reconstruct the evolutionary history of the diverse and ecologically important plant family Proteaceae. This will be used to discover how past environmental changes have produced the biodiversity we see today, and forecast likely future changes to biodiversity under expected r ....Evolutionary history and conservation of an iconic Australian plant group. This project aims to strengthen biodiversity conservation using evolutionary biology. By using new DNA sequencing technologies the project aims to reconstruct the evolutionary history of the diverse and ecologically important plant family Proteaceae. This will be used to discover how past environmental changes have produced the biodiversity we see today, and forecast likely future changes to biodiversity under expected rapid environmental change. The key outcome will be a new methodology for a predictive, forward-looking conservation science that accounts explicitly for the dynamic, evolving nature of biodiversity. The key benefit will be a more robust scientific basis for strategic allocation of limited conservation resources.Read moreRead less
The biosynthesis and evolution of novel semiochemicals in orchids. This project aims to discover new enzymes and genes, unlocking new tools for producing useful chemicals. Many plants secure pollination by attracting animal pollinators. How these crucial interactions evolved remains a mystery. Australia is a world centre for pollination by sexual deception in which hundreds of orchids use novel semiochemicals to sexually attract specific pollinators. In this study we aim to: characterise the bio ....The biosynthesis and evolution of novel semiochemicals in orchids. This project aims to discover new enzymes and genes, unlocking new tools for producing useful chemicals. Many plants secure pollination by attracting animal pollinators. How these crucial interactions evolved remains a mystery. Australia is a world centre for pollination by sexual deception in which hundreds of orchids use novel semiochemicals to sexually attract specific pollinators. In this study we aim to: characterise the biosynthetic pathway and molecular basis of these unique semiochemicals; investigate speciation processes with robust orchid phylogenies; and reveal new insights into the evolution of animal pollination. This should also lead to better design options for managing endangered orchids and developing resilient populations.Read moreRead less