Industrial Transformation Training Centres - Grant ID: IC170100016
Funder
Australian Research Council
Funding Amount
$3,123,492.00
Summary
ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therap ....ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therapeutics. The use of an individual patient’s cellular and molecular research findings will ultimately enable personalised diagnostic and therapeutic decisions.Read moreRead less
Engineering Hybrid Materials with Functional Bioactivity in the GI Tract. This project aims to use an advanced particle engineering approach to develop novel biomaterials with multifunctional activities in the gastrointestinal tract. The project expects to generate new fundamental knowledge of the key interfacial processes that control digestion and identify new pathways for modulating gut microbiome composition. By establishing structure-activity relationships through mechanistic in vitro and i ....Engineering Hybrid Materials with Functional Bioactivity in the GI Tract. This project aims to use an advanced particle engineering approach to develop novel biomaterials with multifunctional activities in the gastrointestinal tract. The project expects to generate new fundamental knowledge of the key interfacial processes that control digestion and identify new pathways for modulating gut microbiome composition. By establishing structure-activity relationships through mechanistic in vitro and in vivo models, the knowledge gain will help guide material design for optimised bioactivity. Technology transfer of the lead formulation through quality by design manufacturing practice is anticipated to position the industry partner for future commercial opportunities within the nutraceutical sector.Read moreRead less
Early career teacher induction: Supporting precarious teachers. This project aims to investigate the ways in which Australian induction policies support precariously employed early career teachers to effectively manage student classroom behaviour. This project expects to generate new knowledge of workforce development and induction experiences of early career teachers employed on casual and short-term contracts. Expected outcomes of this project include alternative policy and practice recommenda ....Early career teacher induction: Supporting precarious teachers. This project aims to investigate the ways in which Australian induction policies support precariously employed early career teachers to effectively manage student classroom behaviour. This project expects to generate new knowledge of workforce development and induction experiences of early career teachers employed on casual and short-term contracts. Expected outcomes of this project include alternative policy and practice recommendations to support the transition of insecure replacement teachers within the profession. The benefits of this research include, improving teachers’ classroom management practices; the retention of new teachers; improving teacher workforce development; and building a healthier education system. Read moreRead less
Finding the targets of natural products in complex botanical extracts. Many plants are used for nutritional and traditional medicine purposes and have demonstrated, evidence based effects. However, standard methods to identify single chemical compounds responsible for the observed effects fail as they rely on a single compound having a single target and ignore the overall effects of many interacting compounds on many targets. In this application we propose a new method to simultaneously identify ....Finding the targets of natural products in complex botanical extracts. Many plants are used for nutritional and traditional medicine purposes and have demonstrated, evidence based effects. However, standard methods to identify single chemical compounds responsible for the observed effects fail as they rely on a single compound having a single target and ignore the overall effects of many interacting compounds on many targets. In this application we propose a new method to simultaneously identify the molecular targets of many compounds in complex plant extracts, along with their subsequent validation by responses in gene expression to the plant extract. This research will revolutionise understanding of the nutritional and medicinal effects of plants and will allow our partners to accelerate commercialisation. Read moreRead less
ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and ne ....ARC Centre of Excellence in Synthetic Biology. The ARC Centre of Excellence in Synthetic Biology (CoESB) will provide the technical innovation critical for Australia to develop a vibrant bioeconomy building on the nation’s strengths in agriculture. For thousands of years we have used microbes to create bread, wine, cheese. Now, our Centre will pioneer new approaches to the design of synthetic microbes, enabling the development of custom-designed microbial communities, synthetic organelles and new to nature biological pathways and enzymes. CoESB will combine engineering with molecular biology to design and construct novel biological systems that can convert biomass from agriculture or waste streams to biofuel, bioplastics and other high-value chemicals.Read moreRead less
Supporting teachers and teaching in flexible and non-traditional schools . This project aims to address a critical gap in knowledge about the experiences and conditions of people who teach in flexible and non-traditional schools in Australia. These schools provide a second chance at education for young people with challenging behaviours and/or learning problems. This project expects to generate new knowledge about the experiences and needs of these teachers, using a combination of in-depth resea ....Supporting teachers and teaching in flexible and non-traditional schools . This project aims to address a critical gap in knowledge about the experiences and conditions of people who teach in flexible and non-traditional schools in Australia. These schools provide a second chance at education for young people with challenging behaviours and/or learning problems. This project expects to generate new knowledge about the experiences and needs of these teachers, using a combination of in-depth research methods. Expected outcomes include detailed understanding of support needs for this workforce. This will significantly benefit teachers, sponsors and principals through recommendations on best practice management of this important work, along with evidence-based training artefacts for staff recruitment and retention.
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Culturally Responsive Schooling. Australian schools are struggling to respond positively to the increasing cultural diversity of the student cohort. The aim of this study is to research how schools become culturally responsive and specifically explores how the affective environments of schools attend to the diverse cultural, academic and emotional needs of their communities. This this study brings together methods borrowed from educational ethnography, critical policy analysis, and educational ....Culturally Responsive Schooling. Australian schools are struggling to respond positively to the increasing cultural diversity of the student cohort. The aim of this study is to research how schools become culturally responsive and specifically explores how the affective environments of schools attend to the diverse cultural, academic and emotional needs of their communities. This this study brings together methods borrowed from educational ethnography, critical policy analysis, and educational action research. The study will inform curriculum and pedagogical reform in schools, changes to teacher education programs, and potentially ameliorate systemic inequality in Australian schooling. Read moreRead less
Equipping Australian teachers today to face AI tomorrow. Applications of Artificial Intelligence (AI) are set to transform society, including how people work and learn. Yet there is very little research about what Australian teachers need to know in order to prepare students to thrive in an AI-rich society and workforce. This study aims to construct a foundational understanding for teaching with and about AI. It will also show how to develop effective networks to empower teachers as active chang ....Equipping Australian teachers today to face AI tomorrow. Applications of Artificial Intelligence (AI) are set to transform society, including how people work and learn. Yet there is very little research about what Australian teachers need to know in order to prepare students to thrive in an AI-rich society and workforce. This study aims to construct a foundational understanding for teaching with and about AI. It will also show how to develop effective networks to empower teachers as active change agents. The expected outcomes will equip teachers with the knowledge and resources to lead the development of Australia’s future AI capability, including through enhanced classroom practices and more creative teacher networks.Read moreRead less
A novel drug class for the effective treatment of Giardia infections. Companion animals play a pivotal role in the lifestyle of the average Australian family. The 9 million cats and dogs, residing in >65% of our households, have provided significant health and well-being benefits to owners, especially during COVID. Ensuring pet health is a primary obligation of pet ownership. Giardia infections (Giardia duodenalis, with 94% of infections in dogs identified as Assemblage A) is the most prevalent ....A novel drug class for the effective treatment of Giardia infections. Companion animals play a pivotal role in the lifestyle of the average Australian family. The 9 million cats and dogs, residing in >65% of our households, have provided significant health and well-being benefits to owners, especially during COVID. Ensuring pet health is a primary obligation of pet ownership. Giardia infections (Giardia duodenalis, with 94% of infections in dogs identified as Assemblage A) is the most prevalent enteric parasite identified globally in dogs. Infection rates can be as high as 75% in puppies. Current treatments are failing due to poor efficacy, resistance and poor adherence to treatment schedules. We have identified a novel, extremely rapid acting series of compounds capable of single shot eradication of Giardia.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100026
Funder
Australian Research Council
Funding Amount
$4,969,663.00
Summary
ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway an ....ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway and barriers faced by the sector, namely improving process efficiencies, enabling early-stage scale-up (cell/tissue) and development of the sector's supply chain. The knowledge created and research undertaken would help to accelerate commercialisation in regenerative medicine, tissue engineering and cell therapies.Read moreRead less