A Sequential Multiple Assignment Randomised Trial (SMART) Of Nursing Interventions To Reduce Pain Associated With Chemotherapy Induced Peripheral Neuropathy
Funder
National Health and Medical Research Council
Funding Amount
$713,418.00
Summary
Modern chemotherapy treatments can result in damage to the peripheral nerves, resulting in a condition called peripheral neuropathy. This condition is characterised by a range of sensory and functional changes that can cause pain and reduced ability to perform daily activities. This project will test various non-pharmacological pain management measures to determine if they are effective in improving the quality of life of patients who experience this problem.
Understanding and Modelling Insect Motion Vision. The interdisciplinary project proposed will offer a stimulating environment for research/training into computational neuroscience, an attractive area for aspiring scientists. We have already demonstrated the feasibility of transferring physiology into applications, and expect this project to deliver functional motion vision models and devices. Our proposed work will have an impact beyond the advancement of neuro-physiology as knowledge gained is ....Understanding and Modelling Insect Motion Vision. The interdisciplinary project proposed will offer a stimulating environment for research/training into computational neuroscience, an attractive area for aspiring scientists. We have already demonstrated the feasibility of transferring physiology into applications, and expect this project to deliver functional motion vision models and devices. Our proposed work will have an impact beyond the advancement of neuro-physiology as knowledge gained is applicable in a range of areas, with applications in miniature unmanned vehicles and collision avoidance detectors in defence and civilian roles. Our project could also assist in the development of artificial intelligence and as a basis for designing implantable artificial eyes.Read moreRead less
Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
Discovery Early Career Researcher Award - Grant ID: DE240100967
Funder
Australian Research Council
Funding Amount
$366,000.00
Summary
Open-world computer vision by detecting and tracking hierarchical objects. This project examines the problem of detecting and tracking objects using computer vision. A fundamental limitation of current algorithms is that they require labelled training data for every object class and therefore cannot be trusted to operate in unconstrained environments. This project aims to address this limitation using novel techniques that incorporate hierarchical relationships between object classes. Expected o ....Open-world computer vision by detecting and tracking hierarchical objects. This project examines the problem of detecting and tracking objects using computer vision. A fundamental limitation of current algorithms is that they require labelled training data for every object class and therefore cannot be trusted to operate in unconstrained environments. This project aims to address this limitation using novel techniques that incorporate hierarchical relationships between object classes. Expected outcomes include new paradigms for algorithm design and evaluation, and establishing the problem as a focus of international research. The key practical benefit would be to accelerate the wider deployment of visual perception in applications such as autonomous vehicles, interactive robotics, and video analysis.Read moreRead less
Target detection in visual clutter. The interdisciplinary nature of the project will offer a stimulating environment for training a postdoctoral worker in the hot topic of computational neuroscience. While computationally expensive solutions to moving target detection in clutter have been implemented using conventional engineering, this project will offer insight into the efficiency of the biological brain (with benefit of millions of years of evolution towards compact, economical and optimal so ....Target detection in visual clutter. The interdisciplinary nature of the project will offer a stimulating environment for training a postdoctoral worker in the hot topic of computational neuroscience. While computationally expensive solutions to moving target detection in clutter have been implemented using conventional engineering, this project will offer insight into the efficiency of the biological brain (with benefit of millions of years of evolution towards compact, economical and optimal solutions). The results will assist development of efficient artificial intelligence. It will also assist our ongoing collaborations with defence partners to develop and apply algorithms in artificial vision systems. Read moreRead less
Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide t ....Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide targets and/or concepts for the pharmacotherapy of obesity.Read moreRead less
Central pathways regulating visceral pain. This project aims to investigate the neural pathways within the spinal cord and brain processing colorectal pain perception. The project aims to identify the spinal cord neurons relaying colorectal signalling into the brain and the influence of descending modulation from the brainstem upon these pathways. The outcomes will greatly benefit fundamental understanding of the central pathways processing visceral pain.
Vision performance in relationship to spectacle lens design. Refractive errors such as short-sightedness, long-sightedness or presbyopia (age related decline in near vision) are the leading causes of visual impairment in the world. Of these, presbyopia affects almost 100% of the population above 45 years of age. This represents over 40% of all Australians. Although spectacles provide a safe and easy means of correcting refractive errors, they affect quality of life due to distorted vision, disco ....Vision performance in relationship to spectacle lens design. Refractive errors such as short-sightedness, long-sightedness or presbyopia (age related decline in near vision) are the leading causes of visual impairment in the world. Of these, presbyopia affects almost 100% of the population above 45 years of age. This represents over 40% of all Australians. Although spectacles provide a safe and easy means of correcting refractive errors, they affect quality of life due to distorted vision, discomfort such as head and neck ache and cosmetic effects. The goals of the project are to better understand the visual performance of young and old people who wear glasses and to develop improved spectacle lens designs to provide clear and comfortable vision over a range of distances.Read moreRead less
Autocalibration without decimation. The insertion of computer generated characters into real footage, the removal of objects from video, and the recovery of 3-dimensional architectural or topographic models from photographs are amongst a growing number of processes used in industry which require highly accurate camera calibration. Autocalibration is thus a prerequisite for these and many other emerging image-based technologies. By developing expertise in this area, and particularly by enabling ....Autocalibration without decimation. The insertion of computer generated characters into real footage, the removal of objects from video, and the recovery of 3-dimensional architectural or topographic models from photographs are amongst a growing number of processes used in industry which require highly accurate camera calibration. Autocalibration is thus a prerequisite for these and many other emerging image-based technologies. By developing expertise in this area, and particularly by enabling more flexible and efficient means of autocalibration, we expect to provide Australian industry with a valuable improvement in the state of the art and a competitive edge in a number of important application areas.Read moreRead less