Development Of A Take-home Rehabilitation Device That Improves Visual Stability And Balance In Patients With Peripheral Vestibular Injury
Funder
National Health and Medical Research Council
Funding Amount
$789,377.00
Summary
The balance system senses head motion via the balance organs, one in each inner ear, and stabilises vision during head movements. Without it, every time you walk, run, or drive on a bumpy road, the world appears to bounce. We have developed a device shown to reliably 'train up' the balance system. Our aim is to develop this device further for effective take-home rehabilitation.
Hear Assure: Saving Natural Hearing During Cochlear Implantation
Funder
National Health and Medical Research Council
Funding Amount
$1,058,537.00
Summary
Cochlear implants provide hearing by electrical stimulation of the hearing nerve. Even people receiving cochlear implants may have natural hearing, which is lost in up to 70% of patients through trauma caused during implantation. This is a major barrier to the adoption of cochlear implants. To overcome this, we will deliver Hear Assure, our novel hearing-monitoring product that is integrated with the cochlear implant, enabling safe positioning of the implant to minimise loss of natural hearing.
Development Of Antimalarial Histone Deacetylase Inhibitors
Funder
National Health and Medical Research Council
Funding Amount
$573,676.00
Summary
Human histone deacetylases (HDACs) are enzymes clinically validated as targets for cancer chemotherapy. Different HDAC enzymes are important for survival of infectious organisms, such as protozoan Plasmodium parasites that cause malaria. This project will develop promising drug leads that kill the parasites without damaging human cells through preclinical studies in mice towards a future clinical trial for the treatment of malaria in humans.