Methodological Research In Meta-analysis And Evidence Synthesis: An Evidence-based Methods Approach
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Systematic reviews synthesize available research to determine whether policy, health service delivery, public health, and clinical interventions are effective. Statistical methods underpin the validity of the findings in systematic reviews. This research will evaluate and develop statistical methods for systematic reviews with the aim of improving the quality of reviews and ensuring healthcare decisions are based on reliable research syntheses.
Therapeutics For Repair And Regeneration Of The Cornea
Funder
National Health and Medical Research Council
Funding Amount
$166,087.00
Summary
Corneal disease is the commonest cause of irreversible blindness and of the 50 million people world-wide who are bilaterally blind, 10 million are blind from corneal involvement. This proposal will address corneal disease by 1. innovative translational research for corneal repair and regeneration; 2. developing evidence-based management guidelines for corneal disease, and 3. by optimising health service delivery.
Preventing Suicide In Young People: A Public Health Approach
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Suicide is the leading cause of death in young Australians. This fellowship aims to lower risk for suicide by testing: a) whether improving the connectedness of adolescents in schools can improve help-seeking, b) whether parents can learn to recognise risk in their children, and c) whether school screening is an appropriate and effective strategy to reduce risk. Practical outcomes will be new programs for youth, new strategies for parents and a better integrated approach for Australian schools.
Systems For Control And Tracking Of Infectious Diseases In A Globalised World
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
Infectious disease informatics now at the forefront of translational research due to the recent rapid growth of microbial genomics, significant advances in molecular diagnostics and increasing demands for real-time biosurveillance. This program of multidisciplinary research will redefine existing paradigms, develop novel systems for surveillance of biothreats and offer new insights into transmission dynamics of pathogens with epidemic potential in Australia.
International Strategies To Reduce Population Salt Intake
Funder
National Health and Medical Research Council
Funding Amount
$428,065.00
Summary
Effective, sustainable and scalable strategies to reduce salt are needed so countries can achieve the global target to reduce salt by 30% by 2025. This research program will support the optimal development of such strategies through trials and intervention research projects, supplemented through a series of systematic reviews and feasibility and cost-effectiveness assessments. The main outcome will be new evidence on the effectiveness of different interventions to support translation globally.
Refining Methods For Obtaining, Synthesising And Interpreting Research Evidence In Surgery
Funder
National Health and Medical Research Council
Funding Amount
$314,312.00
Summary
Research evidence plays a crucial role in improving clinical care. However the main forms of evidence and the tools that facilitate evidence use - namely randomised controlled trials (RCT) and structured systematic reviews of existing research - have had limited application in surgery for a variety of reasons. This project aims to promote the use of research evidence in surgical decision making by developing tools tailored to the predominance of non-RCTs in surgery and surgeons' information need ....Research evidence plays a crucial role in improving clinical care. However the main forms of evidence and the tools that facilitate evidence use - namely randomised controlled trials (RCT) and structured systematic reviews of existing research - have had limited application in surgery for a variety of reasons. This project aims to promote the use of research evidence in surgical decision making by developing tools tailored to the predominance of non-RCTs in surgery and surgeons' information needs.Read moreRead less
Secondary Stroke Prevention: Strategies To Narrow The Gap Between Evidence And Practice
Funder
National Health and Medical Research Council
Funding Amount
$411,803.00
Summary
People who have had a stroke are at increased risk of having another stroke. Secondary stroke prevention is a neglected area of post-stroke care and the uptake of research evidence is poor. Barriers to evidence integration can include problems with the evidence and difficulties at the health professional and/or consumer level. This research will seek to understand the barriers and develop strategies to reduce the gap between evidence and clinical practice in secondary stroke prevention.
Improving Research Evidence Quality Using Individual Patient Data, Prospective Meta-analysis And Trial Registration
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
The quality of evidence we use to make health care decisions can be improved if we use systematic reviews that are planned ahead, that use raw data from each participant and include all the trials that have looked at the clinical problem. This research program will utilise these three ways of obtaining better quality data and will thus make research results more reliable. In particular, we will use these techniques to address health problems in mothers and babies.