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The aim of the Centre is to contribute to the improvement of outcomes for eye-care. This will be achieved by expanding the evidence base for clinical interventions, particularly patient-centred outcomes, informing professionals who deliver eye-care of the evidence base and increasing access to care. The Centre will increase the evidence base by expanding the Australian Corneal Graft Registry, establishing other national registries, and by conducting clinical trials. It will increase access to ca ....The aim of the Centre is to contribute to the improvement of outcomes for eye-care. This will be achieved by expanding the evidence base for clinical interventions, particularly patient-centred outcomes, informing professionals who deliver eye-care of the evidence base and increasing access to care. The Centre will increase the evidence base by expanding the Australian Corneal Graft Registry, establishing other national registries, and by conducting clinical trials. It will increase access to care by establishing new models of eye care delivery for common eye problems in urban and remote populations and by developing efficient and cost-effective pathways to care which utilise a wide range of eye-care professionals.Read moreRead less
Diabetes affects over one million Australians and is an increasing health problem in Australia and worldwide. Diabetes can damage small blood vessels, harming the kidneys and eyes and large blood vessels leading to heart attack, stroke and leg amputation. The research team leading this Centre for Clinical Research Excellence (CCRE) has wide experience in diabetes research and includes experts in diabetes management in hospitals and in the community setting of general practice. There is special e ....Diabetes affects over one million Australians and is an increasing health problem in Australia and worldwide. Diabetes can damage small blood vessels, harming the kidneys and eyes and large blood vessels leading to heart attack, stroke and leg amputation. The research team leading this Centre for Clinical Research Excellence (CCRE) has wide experience in diabetes research and includes experts in diabetes management in hospitals and in the community setting of general practice. There is special expertise in eye disease and in dietary management of diabetes. The research team will conduct research into diabetes, both type 1 diabetes, which usual starts in childhood, and type 2 diabetes that generally affects middle aged or older people, although increasingly is occurring in younger adults as the population becomes more obese. We will focus on the complications, which are common to both types of diabetes, looking for ways to detect them early and prevent them. Our studies will involve groups of up to 10,000 people with diabetes, sometimes followed over 5 or more years. Indigenous Australian groups will be included in the studies as they have a high rates of diabetes and its complications. We will also study ways in which people with type 2 diabetes can be more involved in improving the management of their illness. An exciting part of the study program will involve patients having transplants of insulin producing human islet cells. Although this treatment will be available for only a few patients, it is an important advance towards future treatments using human cells. The CCRE will have a very strong focus on recruiting and training the next generation of doctors and other clinicians involved in diabetes research, including nurses, dietitians and optometrists.Read moreRead less
The Alfred/Monash Centre For Therapeutics And Clinical Research
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
The Centre will provide a national resource for the evaluation of new and existing drugs. It will focus particularly on investigator-initiated research that is not well served by present funding arrangements. With the cost of pharmaceuticals rising at an annual rate of 15-20 percent there is a clear need for independently developed, comparative information on both new and existing agents. It will also address the virtual absence in Australia of a major academic research focus on drug safety and ....The Centre will provide a national resource for the evaluation of new and existing drugs. It will focus particularly on investigator-initiated research that is not well served by present funding arrangements. With the cost of pharmaceuticals rising at an annual rate of 15-20 percent there is a clear need for independently developed, comparative information on both new and existing agents. It will also address the virtual absence in Australia of a major academic research focus on drug safety and pharmacoeconomics.Read moreRead less