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Understanding And Preventing Secondary Degeneration Following CNS Injury
Funder
National Health and Medical Research Council
Funding Amount
$409,147.00
Summary
After neurotrauma, tissue escaping initial injury undergoes secondary degeneration; tissue loss spreads, function worsens. In the complex brain and spinal cord it is difficult to distinguish vulnerable tissue. Using the visual system as a model I will precisely identify cells and processes of secondary degeneration, determine if vulnerable tissue can be rescued by drugs stopping toxic calcium influx and if rescued circuits work properly. The work has implications for neurotrauma and glaucoma.
I am an epidemiologist with a particular interest in injury prevention, injury data systems and safety promotion as they apply to the context of sports injury. I also contribut to the broager field of epidemiology, through the theoretical and methodilogic
Preventing Sports Injuries Through Better Targetting Of Effective Interventions And Monitoring Of Safety Practices And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$756,962.00
Summary
Injuries such as concussion and muscle/joint sprains/strains are a recognised sports medicine issue globally. They are a major barrier towards sustained physical activity participation and a public health concern. Much information about their causes and prevention is yet to be fully disseminated to the community and adopted as standard safety practice. This fellowship will provide a strong evidence-base for sports injury prevention and monitoring, as well as sports safety promotion strategies.
Variational theory for fully nonlinear elliptic equations. This project aims to develop new methods and techniques to solve challenging mathematical problems in fully nonlinear partial differential equations arising in important applications. The project will develop methods and techniques to study these equations’ regularity and variational properties. This project is expected to establish comprehensive theories and enhance and promote Australian participation and leadership in this area of mat ....Variational theory for fully nonlinear elliptic equations. This project aims to develop new methods and techniques to solve challenging mathematical problems in fully nonlinear partial differential equations arising in important applications. The project will develop methods and techniques to study these equations’ regularity and variational properties. This project is expected to establish comprehensive theories and enhance and promote Australian participation and leadership in this area of mathematics.Read moreRead less
Non-linear partial differential equations: Bubbles, layers and stability. This project aims to investigate non-linear elliptic partial differential equations in well-established models in applied sciences. The treatment of them challenges the existing mathematical theory. This project will enrich and expand the mathematical theory in semi-linear elliptic equations to understand the equations under investigation.
New perspectives on nonlocal equations. This project aims at tackling cutting-edge problems in the field of mathematical analysis, with specific focus on nonlocal equations, by introducing innovative approaches and a unified perspective. It focuses on the use of long-range interactions to deeply understand new effects arising in several mathematical problems of great impact.
The research will be performed through stimulating international collaborations, providing exchange opportunities and idea ....New perspectives on nonlocal equations. This project aims at tackling cutting-edge problems in the field of mathematical analysis, with specific focus on nonlocal equations, by introducing innovative approaches and a unified perspective. It focuses on the use of long-range interactions to deeply understand new effects arising in several mathematical problems of great impact.
The research will be performed through stimulating international collaborations, providing exchange opportunities and ideal conditions for students to complete their training.
The expected outcomes include new techniques to solve difficult problems, high impact international research collaborations, training of the next generation of mathematicians and top tier journal publications.Read moreRead less
Singularity and regularity for Monge-Ampere type equations. The Monge-Ampere equation, as a premier nonlinear partial differential equation, arises in several areas including geometry, physics, and optimal transportation. Many important problems and applications are related to the regularity of solutions, which are obstructed by singularities. This project aims to classify the geometry of the singular sets, and to establish a comprehensive regularity theory for general Monge-Ampere type equation ....Singularity and regularity for Monge-Ampere type equations. The Monge-Ampere equation, as a premier nonlinear partial differential equation, arises in several areas including geometry, physics, and optimal transportation. Many important problems and applications are related to the regularity of solutions, which are obstructed by singularities. This project aims to classify the geometry of the singular sets, and to establish a comprehensive regularity theory for general Monge-Ampere type equations by using innovative approaches and developing cutting-edge technologies in partial differential equations. Expected outcomes include the resolution of outstanding open problems. This project will significantly enhance Australia’s leadership and expertise in a major area of mathematics and applications.Read moreRead less
Propagation described by partial differential equations with free boundary. Cutting edge nonlinear mathematics is required to understand many important propagation phenomena in nature, such as the spreading of invasive species or nerve signals. This project aims to systematically investigate nonlinear partial differential equation models that govern the dynamics of such propagations, with emphasis on the development of new approaches that enable deeper insights on the evolution of the propagatin ....Propagation described by partial differential equations with free boundary. Cutting edge nonlinear mathematics is required to understand many important propagation phenomena in nature, such as the spreading of invasive species or nerve signals. This project aims to systematically investigate nonlinear partial differential equation models that govern the dynamics of such propagations, with emphasis on the development of new approaches that enable deeper insights on the evolution of the propagating fronts. The project aims to develop new mathematics for new applications of lasting values.Read moreRead less