Performance And Delivery Of Cardiovascular Health Services
Funder
National Health and Medical Research Council
Funding Amount
$389,860.00
Summary
Heart disease is an important cause of death and disability. The treatments received by patients hospitalised with common heart conditions can vary considerably. At present, there are no systematic methods in place to routinely assess the quality of care or patient outcomes following hospitalisation. This proposal keeps developing quality indicators to measure care experienced by patients admitted following a heart attack or those with heart failure as well for those undergoing common cardiac pr ....Heart disease is an important cause of death and disability. The treatments received by patients hospitalised with common heart conditions can vary considerably. At present, there are no systematic methods in place to routinely assess the quality of care or patient outcomes following hospitalisation. This proposal keeps developing quality indicators to measure care experienced by patients admitted following a heart attack or those with heart failure as well for those undergoing common cardiac procedures.Read moreRead less
Value-Based Healthcare In Elective Coronary Stenting
Funder
National Health and Medical Research Council
Funding Amount
$1,236,881.00
Summary
Coronary stents are wire mesh tubes inserted into cholesterol blockages in heart blood vessels (arteries) thus improving coronary blood flow and alleviating chest pain. Although life saving in acute heart attacks, their value is limited in stable patients and may be associated with severe complications. In partnership with the health department, this project will evaluate how many patients continue to experience chest pain after elective coronary stenting so that can be used more effectively.
Quadruple UltrA-low-dose TReamenT For HypErTension - QUARTET
Funder
National Health and Medical Research Council
Funding Amount
$1,242,865.00
Summary
High blood pressure is common and a major cause of heart disease and stroke. While many people with hypertension are on some treatment, in over half blood pressure targets are not reached and their high blood pressure is hence uncontrolled. In this research we investigate whether an approach that combines 4 types of blood pressure lowering medications at quarter doses into one pill, may be a more effective way of controlling blood pressure and doing this with few side effects.
Translating Science Into Treatment For Ischemic Stroke
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
My team has pioneered research in Australia that has advanced knowledge in the delivery of safer and more effective stroke therapies. I have developed software for the automated processing of multimodal CT imaging to better select patients for stroke therapies. In order to move this cutting-edge imaging technology into routine clinical practice several processes will occur: Implementation, validation and demonstration of patient benefits, and cost effectiveness of CT imaging selection in routine
Improving The Prevention, Treatment And Management Of Cardiovascular & Chronic Disease In The Community
Funder
National Health and Medical Research Council
Funding Amount
$774,540.00
Summary
The identification, prevention and management of cardiovascular and chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises modern epidemiological research methods involving large scale clinical trials, registries and epidemiological modelling to advance our understanding and provide new directions for cardiovascular disease prevention and management.
Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest: A Phase III Multi-Centre Randomised Controlled Trial (The TAME Cardiac Arrest Trial)
Funder
National Health and Medical Research Council
Funding Amount
$2,069,878.00
Summary
The TAME Cardiac Arrest trial will study the ability of higher carbon dioxide (CO2) levels to reduce brain damage, comparing giving patients ‘normal’ to ‘slightly higher than normal’ blood CO2 levels and assessing their ability to return to normal life-tasks. It will be the largest trial ever conducted in heart attack patients in the ICU. This therapy is cost free and, if shown to be effective, will improve thousands of Australian lives, transform clinical practice, and yield major savings.
An Integrated General Practice And Pharmacy-based Intervention To Promote The Prescription And Use Of Appropriate Preventive Medications Among Individuals At High Cardiovascular Risk.
Funder
National Health and Medical Research Council
Funding Amount
$2,380,071.00
Summary
We will conduct a randomised controlled trial that combines three methods to reduce risk factors and improve outcomes for people with cardiovascular disease (CVD). The methods include administration of a polypill, a GP-focused point-of-care intervention, and a pharmacy-led intervention to improve commencement and persistence with taking medications. We expect that integrating these three approaches will lead to large reductions in CVD risk factor levels for participants.
The END RHD CRE: Developing An Endgame For Rheumatic Heart Disease In Australia
Funder
National Health and Medical Research Council
Funding Amount
$2,601,147.00
Summary
Rheumatic heart disease (RHD) is caused by an abnormal immune reaction to some bacterial infections. Although RHD is rare in developed countries, Indigenous Australians still live with the burden of RHD. The END RHD CRE will explore risk factors for RHD, prevention with antibiotics, management of RHD and the potential for vaccine development. Individuals and communities experiencing RHD are integral partners to this work. The CRE will establish a strategy for ending RHD in Australia.
Revealing The Roadblocks: Timely ST-segment Elevation Myocardial Infarction (STEMI) Management Over Total Ischaemic Time In Metropolitan, Regional And Rural Victoria.
Funder
National Health and Medical Research Council
Funding Amount
$72,768.00
Summary
Cardiovascular disease kills one Australian every 12 minutes. Coordinated and prompt medical treatment of heart attack is essential in preventing mortality. This study will identify contributing factors of delay from a frontline clinician and hospital perspective. It is anticipated by understanding the impact these factors have on the delivery of heart attack care, an evidence base is built to support the various clinicians involved, and improve this complex process of care across Victoria.