Circular RNAs As Genome Destabilisers In Human Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,163,220.00
Summary
Mutation of genes are hallmarks of both cancer and neurological disorders. My research group has identified roles for circular RNAs in both these processes. Now, we must close the loop by investigating the mechanism of these processes. This will inform not only why these genes are commonly mutated, but by exploiting the highly stable circular RNAs they may provide early prognostic/diagnostic biomarkers and even represent novel therapeutic targets for cancer and Huntington’s disease.
Advancing Health Economic Evaluation Measurement And Design To Support Priority Setting For Vulnerable Children
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
I bring well developed and unique research skills in child health economics, which is concerned with making sure the health system runs fairly and without waste. This research will make significant advancements in economic evaluation methods to ensure we can fairly evaluate health interventions for children. It will assess equity in how health care is funded for children and provide new information to support a fairer health system for children.
Leveraging The Interface Between Epidemiology And Molecular Biology To Enhance Disease Prevention
Funder
National Health and Medical Research Council
Funding Amount
$1,850,925.00
Summary
Some diseases are becoming more common over time.The increase over time is too rapid to be due to genetics alone. My research program aims to identify the environmental drivers of these diseases so that we can improve the current efforts to stop these diseases before they even begin. The research program has a focus on factors impacting on how a child's brain develops, how food allergy begins and the factors that can prevent multiple sclerosis onset or slow progression.