I am investigating several areas relating to Paediatric surgery in particular the quality and coverage of paediatric surgical trials. The context for this study is to evaluate the current state of paediatric surgical research for methodological rigour, aiming to establish an evidence base and agenda for future trials to improve outcomes in paediatric surgery. The project will involve epidemiological methodology studies and systematic reviews, data linkage and analysis of existing study datasets.
Cancer Risks From Low-dose Ionising Radiation Following Diagnostic Medical Procedures
Funder
National Health and Medical Research Council
Funding Amount
$750,579.00
Summary
Our study investigates cancer risk following exposure to low doses of ionising radiation from medical procedures. Our first major paper linked over 800,000 CT exposures to cancer outcomes in a cohort of almost 11 million young Australians, and found that CT exposure predicted an increased incidence of leukaemia and most solid cancers. In our ongoing work we will incorporate nuclear medicine and other diagnostic x-rays, and estimate radiation dose for individual procedures and to specific organs.
The Role Of Infant Food Allergy In The Natural History And Burden Of Allergic Disease Across The Early Years: The HealthNuts Study
Funder
National Health and Medical Research Council
Funding Amount
$1,722,373.00
Summary
The HealthNuts study of 4600 infants is the world’s first comprehensive population-based study of food allergy with objective measurement of true food allergy and will enable us to understand better the natural history of allergic disorders including food allergy, asthma, eczema and allergic rhinitis and the interplay of risk factors for development of these conditions in the first 6 years of life. The study will have important implications for clinical guidelines and public health policy.
Enterovirus, Vitamin D Status And Inflammation At The Clinical Onset Of Type 1 Diabetes In Childhood
Funder
National Health and Medical Research Council
Funding Amount
$410,542.00
Summary
Type 1 diabetes is a serious disease that is increasing in incidence among Australian children. This project will build on an exsisting study to provide new information on the role of enteroviral infection, vitamin D status and the associated inflammatory changes in blood at the onset of disease.
Risky Business: Improving Understanding Of Young People’s Risky Alcohol Consumption, Drug Use And Sexual Behaviour.
Funder
National Health and Medical Research Council
Funding Amount
$299,564.00
Summary
Increasing numbers of young Australians engage in high-risk alcohol and drug use and sexual behaviour, and experience preventable health outcomes such as injuries, violence and sexually transmitted infections. Despite growing concern, we lack understanding about why young adults take risks, which groups are most at risk, and how different drugs, contexts and settings contribute. Using unique datasets and novel analytical strategies I will generate new knowledge to inform public health responses.
There’s recent evidence that children get leaner and fitter during the school term, but become fatter and less fit over the summer holidays. This may be because of differences in activity and diet: on holidays, children may eat more, be less active and have more screen time. We propose to track the time use, diet, fitness and fatness of 9-11 year old children across three school years. If the pattern is confirmed, we should focus more on the home environment, or perhaps encourage summer camps.
The Physical Activity Continuum In Relation To Cardiometabolic Disease Prevention And Mental Health
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Although incidental physical activity and sleep occupy the large majority of people’s time, we know very little about their joint importance for a healthy heart and a healthy mind. This program of research will examine how physical activity of any intensity and sleep influence cardiovascular and mental health. This research will enable health professionals and public health authorities to develop sustainable and realistic evidence-based lifestyle programs to benefit the health of Australians.
The After-school Period: A Critical Window For Children's Health Behaviours
Funder
National Health and Medical Research Council
Funding Amount
$33,054.00
Summary
The after-school period is important for children’s physical activity and sedentary behaviours. This PhD by publication will build on the first two years of study. Progress-to-date includes defining the after-school period and examining the prevalence and contribution the period makes to daily behaviours over time. This thesis will now examine changes in patterns of after-school behaviours, determine the reliability of survey items assessing correlates of these behaviours and examine correlates.