Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Lively reproduction: do common molecules underlie all vertebrate live birth? Most animals lay eggs, but some (most mammals, including humans and some reptiles) give birth to live young. This project will reveal the molecules underlying the evolution of live birth and fundamental processes of early pregnancy, which potentially will lead to future developments in reproductive science.
Discovery Early Career Researcher Award - Grant ID: DE190101338
Funder
Australian Research Council
Funding Amount
$373,711.00
Summary
Building your future: builder-building coevolution in animal architectures. This project aims to reconstruct how animal architectures change throughout time and how this affects body shapes and functions of their builders. By clarifying the biological role of building behaviour this project will assist in predicting long term responses of wildlife, ecosystems and human life to a changing environment. The project expects to be achieved by comparing the structure, assembly and mechanical performan ....Building your future: builder-building coevolution in animal architectures. This project aims to reconstruct how animal architectures change throughout time and how this affects body shapes and functions of their builders. By clarifying the biological role of building behaviour this project will assist in predicting long term responses of wildlife, ecosystems and human life to a changing environment. The project expects to be achieved by comparing the structure, assembly and mechanical performance of animal architectures with animal morphology and performance in a global phylogenetic framework. This is critical for strategic planning of wildlife and landscape management.Read moreRead less
The link between the angiogenesis of live birth and cancer: a lizard model. The possible link between live birth and cancer will be tested in this project. Lizards that express a growth factor that helps the growth of human cancer tumours will be studied to determine the action of the factor in a whole animal and in human cancer cells.