Monitoring Oxygen Saturation And Heart Rate In The Early Post Natal Period
Funder
National Health and Medical Research Council
Funding Amount
$344,150.00
Summary
In recent years experts have suggested that even a brief exposure to high oxygen concentrations during delivery room (DR) resuscitation is harmful. This has led to a change in our national DR resuscitation guidelines which now advise that 21% oxygen should be considered rather than 100% oxygen for infants of all gestational ages. I aim to develop evidence based guidelines for the use of pulse oximetry in the DR and early post natal period.
Role Of Placental Heme-oxygenase Pathway In Regulating Preterm Neonatal Cardiovascular Function
Funder
National Health and Medical Research Council
Funding Amount
$176,719.00
Summary
Babies born prematurely are more likely to experience problems as a result of being born early with males doing worse than females. The mechanisms causing this difference are unknown. The control of blood flow in the placenta and fetus is essential for normal growth and development. This project will investigate the influence of duration of pregnancy, gender, and exposure to antenatal steroids on pathways that control blood flow in the placenta and the newborn in babies born after prematurely.
Mechanistic Studies Of Medium-chain Fatty Acids In Metabolism And Obesity.
Funder
National Health and Medical Research Council
Funding Amount
$316,449.00
Summary
A major factor underpinning metabolic disorders such as obesity and diabetes is unlimited access to high-fat diets. However, not all lipids have detrimental effects on metabolic health. Diets rich in medium-chain fatty acids are associated with reduced adiposity and preserved insulin action. This project will examine the mechanisms that underlie the beneficial effects of MCFA, with focus on a novel MCFA-receptor (GPR84) as a potential therapeutic target in the treatment of metabolic disease.