Immediate And Long-term Safety Of Prescription Opioids In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$447,603.00
Summary
Little is known about the consequences of prescription opioid use during pregnancy for fetal and childhood development. In this study covering over 5 million mother-child pairs, we will investigate the safety of opioid use in pregnancy, by combining rich data sources from Australia, and the 5 Nordic countries. We will translate findings into policy, guidelines and messaging for medicine consumers and prescribers to protect the safety of women and children.
Centre Of Research Excellence In Cognitive Health: Evidence, Intervention And Population Modelling
Funder
National Health and Medical Research Council
Funding Amount
$2,499,872.00
Summary
Cognitive health is essential for productivity at all ages. Common chronic diseases such as diabetes, and risk factors such as smoking, can reduce cognitive function and increase risk of cognitive decline. Our Centre aims to build evidence about the things that impact on cognitive health and lead to cognitive decline; to develop methods of reducing cognitive decline; and to measure the impact of cognitive impairment at the national level to inform the government on costs and planning.
Improving Outcomes In Systemic Autoimmune Disease: A Collaborative And Interdisciplinary Program Of Research
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
The multi-organ autoimmune diseases ‘scleroderma’ and ‘lupus’ have a profound negative impact on quality of life and life expectancy. The overall goal of my research is to improve patient outcomes in these two diseases. My collaborative and interdisciplinary research program entails quantifying disease burden, identifying patient subsets, optimising screening for complications, developing outcome measures for use in practice and research, and trialing new therapies.
Burden Of Rheumatic Heart Disease (RHD) And Impact Of Prevention Strategies: Comprehensive Evidence To Drive The RHD Endgame
Funder
National Health and Medical Research Council
Funding Amount
$960,655.00
Summary
Rheumatic heart disease is chronic damage to the heart valves caused by repeated bouts of acute rheumatic fever. Both are preventable, yet rates among Indigenous Australians are of the highest recorded. We propose to undertake the first multi-jurisdictional study of these conditions to determine trends in occurrence and evaluate the impact of existing interventions in Australia. Findings will be used to inform the development of a roadmap to remove RHD as a public health problem in Australia.
Patterns Of Care And Outcomes For Subarachnoid Haemorrhage: A Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$125,625.00
Summary
As many as 30% of people with subarachnoid haemorrahge (SAH) die within 90 days. Survivors are often left disabled. Death rates appear to be decreasing. Identifying health service variables that impact positively on survival has the potential to inform health policy and practice. We will describe variations in mortality, hospital re-admission and patterns of care. The study will observe the uptake of new SAH management including new neurosurgical techniques.
Simple Cognitive Behavioural Treatment Of The Symptoms Of Trauma In First Episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$173,898.00
Summary
Psychotic disorders (such as schizophrenia) are some of the most severe forms for mental disorder. Many people with psychosis have experienced trauma in childhood or as a result of their psychosis, and have developed post-traumatic stress disorder as a result. The aim of the proposed study is to test whether a simple psychological intervention is effective in reducing trauma symptoms in FEP. This has the potential to significantly improve outcomes in FEP.
Long-term Outcome Of Individuals Who Had A First-episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$1,344,905.00
Summary
The long-term illness course and outcomes of patients treated for first episode psychosis are poorly understood especially in terms of important domains such as social and vocational functioning, physical health, and quality of life. This treated cohort study of a sample of 786 patients, 15 years after their first episode of psychosis will be one of the longest and largest conducted to date. Results of the study will inform clinical practice and policy development.
Innovative Approaches To Improve Maternal And Neonatal Outcomes In Low-resource Settings
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
As part of a large antenatal field trial field I will recruit a sub-set of 1840 women; half will will receive a kit containing items intended to improve outcomes for both mother and baby, and half will receive standard care. Health outcomes for mothers and babies between the two groups will be compared to evaluate the impact and acceptability of the intervention to improve health outcomes for mothers and their infants.