Improving Pain And Movement Outcomes In Symptomatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
People fear getting painful knee osteoarthritis (OA) more than any other disease – it is seen as progressive and incurable. It often stops people from moving and staying healthy, resulting in an enormous burden on sufferers and the health care system. This program of research aims to understand what brain & nervous system processes might underlie these pain and movement problems and whether new brain-targeting treatment helps. This will allow us to better match treatment to what patients need.
New Approaches To The Prevention And Treatment Of Musculoskeletal Disease
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
In Australia, musculoskeletal conditions like osteoarthritis and back pain are responsible for much pain and disability. Although until recently these were considered to be purely due to wear and tear, Associate Professor Wluka, a rheumatologist, has shown that these are not simply due to overuse and loading but metabolic factors also play a role. This award will enable the role of these factors to be examined and new therapies tested in clinical trials, providing evidence to improve the managem ....In Australia, musculoskeletal conditions like osteoarthritis and back pain are responsible for much pain and disability. Although until recently these were considered to be purely due to wear and tear, Associate Professor Wluka, a rheumatologist, has shown that these are not simply due to overuse and loading but metabolic factors also play a role. This award will enable the role of these factors to be examined and new therapies tested in clinical trials, providing evidence to improve the management of these conditions.Read moreRead less
Bridging The Fields Of Cartilage, Bone Marrow And Cancer Research
Funder
National Health and Medical Research Council
Funding Amount
$470,144.00
Summary
This Fellowship will bring together technologies and expertise in cartilage tissue engineering, in vitro haematopoietic stem cell (HSC) self-renewal, HSC transplantation, and in platform development for the study of prostate cancer bone metastasis. By exploiting the intersection of multiple diseases and tissue platforms, we hope to be able to contribute significantly to improved cartilage repair, bone marrow/cord blood stem cell transplants, and the treatment of metastatic prostate cancer.
Improving Musculoskeletal Pain By Matching The Right Treatment With The Right Patient
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
Musculoskeletal pain is common, disabling, and costly in Australia. Current treatment options are poor. This program of research uses clinical trials to investigate new therapy options for osteoarthritis and chronic low back pain. These studies aim to provide new effective treatment options for patients that can improve pain, slow joint damage and decrease the overall burden of musculoskeletal disease.
Improving The Prevention And Outcomes Of Knee And Hip Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
Osteoarthritis is a major public health problem. No current treatment slows disease progression with end-stage osteoarthritis treated by joint replacement surgery. This project will identify new approaches for the prevention and treatment of osteoarthritis and the improvement of patients’ outcomes after total joint replacement surgery. The findings will have both public health and clinical impact, informing clinical practice of strategies to improve the prevention and outcomes of osteoarthritis.