Untangling Complex Molecular Spectra with an Optical Frequency Comb. The exhaled breath is a rich source of information about the inner life of the human body - but untangling this complicated molecular mixture into a quantitative measurement of its constituent components is currently an unsolved problem. This project aims to develop a new instrument that leverages the Nobel Prize winning technology of the optical frequency comb to enable analysis of such mixtures. It is expected that by combini ....Untangling Complex Molecular Spectra with an Optical Frequency Comb. The exhaled breath is a rich source of information about the inner life of the human body - but untangling this complicated molecular mixture into a quantitative measurement of its constituent components is currently an unsolved problem. This project aims to develop a new instrument that leverages the Nobel Prize winning technology of the optical frequency comb to enable analysis of such mixtures. It is expected that by combining a frequency comb source, with an innovative detector and a highly sensitive sampling system, a real-time spectral signature of each sample will be generated. Computational techniques developed by the radio astronomy community will then be used to extract concentrations of individual molecular components at the parts-per-billion level.Read moreRead less
Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. ....Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. The development of technological innovations based on fabricated nanomaterials, will also enhance capacity in frontier technology such as nanotechnology, and build Australia’s strength in using new biosensing technologies.Read moreRead less
Compact and versatile chip lasers for three-dimensional mine surveying. This project will bring together a world leading mine survey company, The University of Adelaide and Macquarie University researchers, to develop an 'eye-safe' micro laser for high resolution three-dimensional laser-mapping. The recently developed and patented 'chip' laser will allow the realisation of a compact, enhanced range laser-radar with unmatched resolution.
Extreme temperature monitoring for minerals and metals processing. This project aims to extend the capabilities of the optical fibre temperature sensor technology developed by the research team, based on microstructured optical fibres and femtosecond laser ablation fibre Bragg gratings, to conduct a range of measurements inside industrial furnace environments that are impossible using existing technology. This device will also be validated within the furnaces located at the minerals and metals p ....Extreme temperature monitoring for minerals and metals processing. This project aims to extend the capabilities of the optical fibre temperature sensor technology developed by the research team, based on microstructured optical fibres and femtosecond laser ablation fibre Bragg gratings, to conduct a range of measurements inside industrial furnace environments that are impossible using existing technology. This device will also be validated within the furnaces located at the minerals and metals processing facility operated by Nyrstar in Port Pirie. This project is designed to enable smelter operators to improve production efficiency, reduce energy consumption, and minimise equipment failure.Read moreRead less
Creating a national time and frequency network for Australia. This project will develop the means to distribute accurate time and frequency across the Australian continent via an optical fibre network. This network will meet the needs of future telecommunications, science and astronomy projects including the Australian bid for the Square Kilometre Array radio-astronomy project.
A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of ....A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of interest to capture the miRNA. Application of a magnetic field allows the levels of miRNA to be detected electrochemically. The expected outcome is a commercialisable biosensor for miRNA both as a diagnostic early detection device and a prognostic device for a range of miRNA biomarkers.Read moreRead less
Electrochemical biosensors for detection of cardiac disease markers in blood. Cardiovascular diseases leading to heart failure have a prevalence of over 16 per cent in Australia. The social, economic and health burden is higher than for any other disease group. Hence, it is critically important to develop fit-for-purpose sensors of known cardiac biomarkers, which alert patients and clinicians of the risk of imminent heart failure.
Smart Bungs for wine monitoring. 'Smart Bung' sensors will use optical fibres to monitor wine production using only nano- to microlitre-scale volumes, significantly reducing wastage and improving quality. They will serve as 'early warning devices' and will ensure that Australia's wine industry maintains its outstanding international reputation for excellence and innovation.
Development of an implantable device to monitor lactate levels in blood: Monitoring the Performance of Australian athletes using Biosensor Technology. Sport is a critical area for social and economic investments. Novel medical monitoring systems using implantable biosensors will ensure optimal training programs for Australian athletes and maintain international competitiveness. Here we are developing a biosensor for real-time monitoring of lactate levels in athletes using frontier porous semicon ....Development of an implantable device to monitor lactate levels in blood: Monitoring the Performance of Australian athletes using Biosensor Technology. Sport is a critical area for social and economic investments. Novel medical monitoring systems using implantable biosensors will ensure optimal training programs for Australian athletes and maintain international competitiveness. Here we are developing a biosensor for real-time monitoring of lactate levels in athletes using frontier porous semiconductor technology and smart telemetry protocols to transfer the readings to a remote base unit. These highly innovative devices and the materials that they are made from have enormous commercial potential in biomedical engineering. There is a strong potential for Australia to have an important stake in this area by combining expertise in engineering, chemistry and nanostructured materials.Read moreRead less
Laser Airborne Methane Sensor. Fugitive emissions of methane represent a significant economic loss to the natural gas industry. This project aims to develop a new laser based methane sensing platform for deployment on fixed wing aircraft. This aims to allow the spatial concentration of methane to be mapped rapidly over a broad area with unprecedented spatial resolution allowing sources to be rapidly identified and the gas captured for economic benefit. The testing of this system on an airborne p ....Laser Airborne Methane Sensor. Fugitive emissions of methane represent a significant economic loss to the natural gas industry. This project aims to develop a new laser based methane sensing platform for deployment on fixed wing aircraft. This aims to allow the spatial concentration of methane to be mapped rapidly over a broad area with unprecedented spatial resolution allowing sources to be rapidly identified and the gas captured for economic benefit. The testing of this system on an airborne platform is possible in this timeframe because of the plan to modify an existing system provided by the Partner Organisation.Read moreRead less